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Note 6 - Share-based Compensation - Noncash Stock Option Compensation (Details) - USD ($) | 3 Months Ended
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Mar. 31, 2025 | Mar. 31, 2024
Stock-based compensation | $ 225,030 | $ 306,478
Share based compensation expense - stock option | 225,030 | 306,478
Share-Based Payment Arrangement, Option [Member] |  |
Stock-based compensation | 177,294 | 190,269
Share based compensation expense - stock option | 177,294 | 190,269
Restricted Stock Units (RSUs) [Member] |  |
Stock-based compensation | 47,736 | 116,209
Share based compensation expense - stock option | 47,736 | 116,209
General and Administrative Expense [Member] |  |
Stock-based compensation | (207,996) | (294,034)
Share based compensation expense - stock option | (207,996) | (294,034)
Research and Development Expense [Member] |  |
Stock-based compensation | 17,034 | 12,444
Share based compensation expense - stock option | $ 17,034 | $ 12,444

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