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Segment Information | 6 Months Ended
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Jun. 30, 2025
Segment Reporting [Abstract] |
Segment Information | 11. Segment Information Operating segments are identified as components of an enterprise about which separate discrete financial information is available for evaluation by the chief operating decision-maker in making decisions regarding resource allocation and assessing performance. The Company is a clinical-stage biopharmaceutical company and has not generated any product revenue from its CAB antibody-based products. The Company’s operations are organized and reported as a single reportable segment, which includes all activities related to the discovery, development, and commercialization of its CAB products. The Company’s CODM, its chief executive officer, reviews operating results on an aggregate basis and manages the operations as a single operating segment. The measure of segment assets is reported on the balance sheets as total assets. The CODM evaluates performance and allocates resources based on net income or loss that also is reported on the condensed statements of operations and comprehensive loss as net loss, and cash used in operations. The following table provides R&D expenses by program with a reconciliation to net loss for the periods indicated, which are regularly reviewed by the CODM:
| Three Months Ended June 30, |  |  | Six Months Ended June 30, |
| 2025 |  |  | 2024 |  |  | 2025 |  |  | 2024 |
| (in thousands) |  |  |  |
Program expenses: |  |  |  |  |  |  |  |  |  |  |
Mecbotamab vedotin, BA3011 (CAB AXL-ADC) | $ | 3,051 |  |  | $ | 3,500 |  |  | $ | 5,992 |  |  | $ | 8,833 |
Ozuriftamab vedotin, BA3021 (CAB ROR2-ADC) |  | 1,208 |  |  |  | 2,023 |  |  |  | 3,285 |  |  |  | 4,564 |
Evalstotug, BA3071 (CAB CTLA-4) |  | 3,045 |  |  |  | 2,447 |  |  |  | 3,224 |  |  |  | 5,055 |
BA3182 (CAB EpCAM x CAB CD3) |  | 2,136 |  |  |  | 1,206 |  |  |  | 3,076 |  |  |  | 2,377 |
Other CAB Programs |  | 728 |  |  |  | 1,629 |  |  |  | 1,799 |  |  |  | 3,258 |
Total program expenses |  | 10,168 |  |  |  | 10,805 |  |  |  | 17,376 |  |  |  | 24,087 |
Personnel and related |  | 2,145 |  |  |  | 3,347 |  |  |  | 5,603 |  |  |  | 6,770 |
Equity-based compensation |  | 567 |  |  |  | 1,164 |  |  |  | 1,342 |  |  |  | 2,244 |
Facilities and other |  | 804 |  |  |  | 882 |  |  |  | 1,718 |  |  |  | 1,949 |
Total research and development expenses |  | 13,684 |  |  |  | 16,198 |  |  |  | 26,039 |  |  |  | 35,050 |
General and administrative expenses |  |  |  |  |  |  |  |  |  |  |
Personnel and related |  | 1,577 |  |  |  | 1,938 |  |  |  | 3,680 |  |  |  | 3,906 |
Equity-based compensation |  | 810 |  |  |  | 1,332 |  |  |  | 1,680 |  |  |  | 2,553 |
Facilities and other |  | 2,576 |  |  |  | 2,504 |  |  |  | 4,862 |  |  |  | 4,920 |
Total general and administrative expenses |  | 4,963 |  |  |  | 5,774 |  |  |  | 10,222 |  |  |  | 11,379 |
Interest and other income (loss) |  | (64 | ) |  |  | 900 |  |  |  | 2,216 |  |  |  | 2,123 |
Net loss and comprehensive loss | $ | (18,711 | ) |  | $ | (21,072 | ) |  | $ | (34,045 | ) |  | $ | (44,306 | )

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- Definition The entire disclosure for reporting segments including data and tables. Reportable segments include those that meet any of the following quantitative thresholds a) it's reported revenue, including sales to external customers and intersegment sales or transfers is 10 percent or more of the combined revenue, internal and external, of all operating segments b) the absolute amount of its reported profit or loss is 10 percent or more of the greater, in absolute amount of 1) the combined reported profit of all operating segments that did not report a loss or 2) the combined reported loss of all operating segments that did report a loss c) its assets are 10 percent or more of the combined assets of all operating segments. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 21 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-21 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name 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