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Income Taxes - Reconciliation of income tax benefit (Details) - USD ($) | 12 Months Ended
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Dec. 31, 2020 | Dec. 31, 2019
Federal and state provision (benefit) for income taxes |  |
Federal provision (benefit) for income taxes | $ 0 | $ 0
State provision (benefit) for income taxes | $ 0 | $ 0
Reconciliation of income tax benefit computed at the statutory federal income tax rate to income taxes as reflected in the financial statements |  |
Federal income tax benefits at statutory rate | 21.00% | 21.00%
State and local tax, net of federal benefit | 7.60% | 8.00%
Permanent differences | (0.80%) | 0.40%
Research and development credit | 1.90% |
Change in valuation allowance | (29.70%) | (29.40%)
Effective income tax rate | 0.00% | 0.00%

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