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Income Taxes - Reconciliation of income tax benefit (Details) - USD ($)
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Federal and state provision (benefit) for income taxes    
Federal provision (benefit) for income taxes $ 0 $ 0
State provision (benefit) for income taxes $ 0 $ 0
Reconciliation of income tax benefit computed at the statutory federal income tax rate to income taxes as reflected in the financial statements    
Federal income tax benefits at statutory rate 21.00% 21.00%
State and local tax, net of federal benefit 7.60% 8.00%
Permanent differences (0.80%) 0.40%
Research and development credit 1.90%  
Change in valuation allowance (29.70%) (29.40%)
Effective income tax rate 0.00% 0.00%