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Stock-Based Compensation (Tables) | 12 Months Ended
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Dec. 31, 2021
Stock-Based Compensation |
Schedule of stock-based compensation expense | Stock-based compensation expense in the statements of operations, including the fair value of stock awards to consultants and advisors for services rendered, for the years ended December 31, 2021 and 2020 was as follows:
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Year Ended
​ | ​ | December 31,
​ |  | 2021 |  | 2020
​ |  | ​ |  |  | ​ |
Research and development | ​ | $ | 2,016,745 | ​ | $ | 138,704
General and administrative | ​ |  | 2,680,882 | ​ |  | 1,726,209
​ | ​ | $ | 4,697,627 | ​ | $ | 1,864,913
Schedule of stock option activity | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ |  | ​ |  | ​ | ​ |  | Weighted |  | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | Average | ​ | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | Remaining | ​ | ​
​ | ​ | ​ | ​ | Weighted | ​ | Contractual | ​ | Aggregate
​ | ​ | Number of | ​ | Average | ​ | Term | ​ | Intrinsic
​ | ​ | Shares | ​ | Exercise Price | ​ | (Years) | ​ | Value
Outstanding at December 31, 2019 |  | 352,282 | ​ |  | $ 0.19 | ​ |  |  |
Granted |  | 810,000 | ​ |  | 3.46 | ​ |  |  |
Exercised |  | (48,435) | ​ |  | 0.19 | ​ |  |  |
Forfeited |  | (2,381) | ​ |  | 0.14 | ​ |  |  |
Outstanding at December 31, 2020 |  | 1,111,466 | ​ |  | 2.57 | ​ |  |  |
Granted |  | 538,095 | ​ |  | 33.78 | ​ |  |  |
Exercised |  | (159,813) | ​ |  | 2.83 | ​ |  |  |
Outstanding at December 31, 2021 |  | 1,489,748 | ​ |  | 13.82 | ​ | 8.4 |  | $ 14,325,377
Exercisable at December 31, 2021 |  | 1,105,568 | ​ |  | 5.87 | ​ | 7.9 |  | $ 14,325,377
Schedule of weighted average assumptions used to determine fair value of options | ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ |  | Year Ended |  |  | Year Ended |
​ | ​ | December 31, 2021 |  | ​ | December 31, 2020 |
Risk-free interest rate |  | 1.17 | % |  | 0.38 | %
Expected life |  | 5.3 | ​ |  | 5.0 | ​
Expected volatility |  | 113 | % |  | 80 | %
Expected dividend yield |  | — | ​ |  | — | ​

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- Definition Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 14.F) -URI http://asc.fasb.org/extlink&oid=122041274&loc=d3e301413-122809 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5047-113901 + Details
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- Definition Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (d) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (e) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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