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Stock-Based Compensation (Tables) | 12 Months Ended
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Dec. 31, 2022
Stock-Based Compensation |
Schedule of stock-based compensation expense | ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Year Ended
​ | ​ | December 31,
​ | ​ | 2022 |  | 2021
General and administrative | ​ | $ | 5,778,117 | ​ | $ | 2,680,882
Research and development | ​ |  | 3,374,403 | ​ |  | 2,016,745
​ | ​ | $ | 9,152,520 | ​ | $ | 4,697,627
​
Schedule of stock option activity | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ |  | ​ |  | ​ | ​ |  | Weighted |  | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | Average | ​ | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | Remaining | ​ | ​
​ | ​ | ​ | ​ | Weighted | ​ | Contractual | ​ | Aggregate
​ | ​ | Number of | ​ | Average | ​ | Term | ​ | Intrinsic
​ | ​ | Shares | ​ | Exercise Price | ​ | (Years) | ​ | Value
Outstanding at December 31, 2020 |  | 1,111,466 | ​ |  | $ 2.57 | ​ |  |  |
Granted |  | 538,095 | ​ |  | $ 33.78 | ​ |  |  |
Exercised |  | (159,813) | ​ |  | $ 2.83 | ​ |  |  |
Forfeited |  | — | ​ |  | $ - | ​ |  |  |
Outstanding at December 31, 2021 |  | 1,489,748 | ​ |  | $ 13.82 | ​ | ​ | ​ | ​
Granted | ​ | 348,294 | ​ | ​ | $ 15.90 | ​ | ​ | ​ | ​
Exercised | ​ | (70,101) | ​ | ​ | $ 1.97 | ​ | ​ | ​ | ​
Forfeited | ​ | (110,599) | ​ | ​ | $ 25.93 | ​ | ​ | ​ | ​
Outstanding at December 31, 2022 |  | 1,657,342 | ​ |  | $ 13.95 | ​ | 6.2 |  | $ 9,907,660
Exercisable at December 31, 2022 | ​ | 1,310,667 | ​ | ​ | $ 11.64 | ​ | 5.4 |  | $ 9,591,460
​
Schedule of weighted average assumptions used to determine fair value of options | ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ |  | Year Ended |  |  | Year Ended |
​ | ​ | December 31, 2022 |  | ​ | December 31, 2021 |
Risk-free interest rate |  | 2.24 | % |  | 1.17 | %
Expected life |  | 5.9 | ​ |  | 5.3 | ​
Expected volatility |  | 112 | % |  | 113 | %
Expected dividend yield |  | — | ​ |  | — | ​
​

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- Definition Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (d) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (e) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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