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Stock-Based Compensation (Tables)

12 Months Ended

Dec. 31, 2022

Stock-Based Compensation

Schedule of stock-based compensation expense

​

​	​	​	​	​	​	​
​	​	Year Ended
​	​	December 31,
​	​	2022			2021
General and administrative	​	$	5,778,117	​	$	2,680,882
Research and development	​		3,374,403	​		2,016,745
​	​	$	9,152,520	​	$	4,697,627

​

Schedule of stock option activity

​

​	​	​	​	​	​	​	​	​	​
​		​		​	​		Weighted		​
​	​	​	​	​	​	​	Average	​	​
​	​	​	​	​	​	​	Remaining	​	​
​	​	​	​	Weighted		​	Contractual	​	Aggregate
​	​	Number of	​	Average		​	Term	​	Intrinsic
​	​	Shares	​	Exercise Price		​	(Years)	​	Value
Outstanding at December 31, 2020		1,111,466	​		$ 2.57	​
Granted		538,095	​		$ 33.78	​
Exercised		(159,813)	​		$ 2.83	​
Forfeited		—	​		$ -	​
Outstanding at December 31, 2021		1,489,748	​		$ 13.82	​	​	​	​
Granted	​	348,294	​	​	$ 15.90	​	​	​	​
Exercised	​	(70,101)	​	​	$ 1.97	​	​	​	​
Forfeited	​	(110,599)	​	​	$ 25.93	​	​	​	​
Outstanding at December 31, 2022		1,657,342	​		$ 13.95	​	6.2		$ 9,907,660
Exercisable at December 31, 2022	​	1,310,667	​	​	$ 11.64	​	5.4		$ 9,591,460

​

Schedule of weighted average assumptions used to determine fair value of options

​

​	​	​	​	​	​	​
​		Year Ended			Year Ended
​	​	December 31, 2022		​	December 31, 2021
Risk-free interest rate		2.24	%		1.17	%
Expected life		5.9	​		5.3	​
Expected volatility		112	%		113	%
Expected dividend yield		—	​		—	​

​

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Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement.

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- Definition

Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value.

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Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions.

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