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Stock-Based Compensation (Details) - USD ($)
3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Dec. 31, 2022
Jun. 01, 2021
May 31, 2021
Stock-Based Compensation          
Stock-based compensation expense $ 1,542,338 $ 3,434,944      
Options granted 81,705        
Weighted average exercise price $ 13.17        
General and administrative          
Stock-Based Compensation          
Stock-based compensation expense $ 769,102 2,245,043      
Research and development          
Stock-Based Compensation          
Stock-based compensation expense $ 773,236 $ 1,189,901      
Stock Options          
Stock-Based Compensation          
Weighted average grant date fair value $ 11.73        
Exercise of stock options, shares 52,755 63,353      
Options outstanding 1,686,292   1,657,342    
Options, vested and exercisable 1,366,837   1,310,667    
Stock Options | Weighted average          
Stock-Based Compensation          
Expected term (in years) 5 years 7 months 6 days        
Risk-free interest rate 3.42%        
Expected volatility 131.80%        
Dividend yield (as a percent) 0.00%        
Stock Options | Service-based vesting, quarterly installments          
Stock-Based Compensation          
Vesting period 2 years        
Term of award (in years) 10 years        
Previous Plans          
Stock-Based Compensation          
Shares available for future grants 0        
2019 Plan          
Stock-Based Compensation          
Shares authorized       2,000,000 1,000,000
Shares available for future grants 311,169