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Stock-Based Compensation (Tables) | 12 Months Ended
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Dec. 31, 2023
Stock-Based Compensation |
Schedule of stock-based compensation expense | Stock-based compensation expense in the statements of operations, including the fair value of stock awards to consultants and advisors for services rendered, for the years ended December 31, 2023 and 2022 was as follows:
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Year Ended
​ | ​ | December 31,
​ |  | 2023 |  | 2022
General and administrative | ​ | $ | 2,414,867 | ​ | $ | 5,778,117
Research and development | ​ |  | 2,213,539 | ​ | ​ | 3,374,403
​ | ​ | $ | 4,628,406 | ​ | $ | 9,152,520
Schedule of stock option activity | Stock option activity for the years ended December 31, 2023, and 2022, was as follows: ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ |  | ​ |  | ​ | ​ |  | Weighted | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | Average | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | Remaining | ​ | ​ | ​
​ | ​ | ​ | ​ | Weighted | ​ | Contractual | ​ | Aggregate
​ | ​ | Number of | ​ | Average | ​ | Term | ​ | Intrinsic
​ | ​ | Shares | ​ | Exercise Price | ​ | (Years) |  | Value
Outstanding at December 31, 2021 |  | 1,489,748 | ​ | $ | 13.82 | ​ |  | ​ |  |
Granted |  | 348,294 | ​ | $ | 15.90 | ​ |  | ​ |  |
Exercised |  | (70,101) | ​ | $ | 1.97 | ​ |  | ​ |  |
Forfeited |  | (110,599) | ​ | $ | 25.93 | ​ |  | ​ |  |
Outstanding at December 31, 2022 |  | 1,657,342 | ​ | $ | 13.95 | ​ | ​ | ​ | ​ | ​
Granted | ​ | 367,329 | ​ | $ | 8.57 | ​ | ​ | ​ | ​ | ​
Exercised | ​ | (59,897) | ​ | $ | 0.14 | ​ | ​ | ​ | ​ | ​
Forfeited | ​ | (10,000) | ​ | $ | 4.39 | ​ | ​ | ​ | ​ | ​
Outstanding at December 31, 2023 |  | 1,954,774 | ​ | $ | 13.41 | ​ | 6.10 | ​ | $ | 17,862,936
Exercisable at December 31, 2023 | ​ | 1,600,577 | ​ | $ | 14.30 | ​ | 5.39 | ​ | $ | 14,532,422
​
Schedule of weighted average assumptions used to determine fair value of options | ​
​ | ​ | ​ | ​ | ​ | ​
​ |  | Year Ended |  | Year Ended |
​ | ​ | December 31, 2023 |  | December 31, 2022 |
Risk-free interest rate |  | 4.17 | % | 2.24 | %
Expected life |  | 5.5 | ​ | 5.9 | ​
Expected volatility |  | 120 | % | 112 | %
Expected dividend yield |  | — | ​ | — | ​

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- Definition Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1) -Publisher FASB -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2 + Details
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- Definition Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -Publisher FASB -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (d) -SubTopic 10 -Topic 718 -Publisher FASB -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (e) -SubTopic 10 -Topic 718 -Publisher FASB -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Topic 718 -SubTopic 10 -Subparagraph (f)(2) -Name Accounting Standards Codification -Paragraph 2 -Section 50 -Publisher FASB -URI https://asc.fasb.org//1943274/2147480429/718-10-50-2 + Details
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