<SEC-DOCUMENT>0001104659-24-073992.txt : 20240621
<SEC-HEADER>0001104659-24-073992.hdr.sgml : 20240621
<ACCEPTANCE-DATETIME>20240621171556
ACCESSION NUMBER:		0001104659-24-073992
CONFORMED SUBMISSION TYPE:	S-8
PUBLIC DOCUMENT COUNT:		6
FILED AS OF DATE:		20240621
DATE AS OF CHANGE:		20240621
EFFECTIVENESS DATE:		20240621

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Annovis Bio, Inc.
		CENTRAL INDEX KEY:			0001477845
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				262540421
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-8
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-280417
		FILM NUMBER:		241061385

	BUSINESS ADDRESS:	
		STREET 1:		101 LINDENWOOD DRIVE, SUITE 225
		CITY:			MALVERN
		STATE:			PA
		ZIP:			19355
		BUSINESS PHONE:		484-875-3192

	MAIL ADDRESS:	
		STREET 1:		101 LINDENWOOD DRIVE, SUITE 225
		CITY:			MALVERN
		STATE:			PA
		ZIP:			19355

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	QR Pharma, Inc.
		DATE OF NAME CHANGE:	20091202
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-8
<SEQUENCE>1
<FILENAME>tm2417417d1_s8.htm
<DESCRIPTION>S-8
<TEXT>
<HTML>
<HEAD>
     <TITLE></TITLE>
</HEAD>
<BODY STYLE="font: 10pt Times New Roman, Times, Serif">

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>As filed with the Securities and Exchange Commission
on June&#8239;21, 2024</B>&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 6in; text-align: right"><B>Registration No.&#8239;333-&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<!-- Field: Rule-Page --><DIV STYLE="margin-top: 12pt; margin-bottom: 3pt; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 2pt solid; border-bottom: Black 1pt solid">&#8239;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>UNITED STATES</B>&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>SECURITIES AND EXCHANGE COMMISSION</B>&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Washington, D.C. 20549</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>FORM&#8239;S-8</B>&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>REGISTRATION STATEMENT UNDER THE SECURITIES
ACT OF 1933</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 14pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>ANNOVIS BIO,&#8239;INC.</B>&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>(Exact name of registrant as specified in its
charter)</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 51%; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Delaware</B></FONT></TD>
    <TD STYLE="width: 1%">&#8239;</TD>
    <TD STYLE="width: 1%">&#8239;</TD>
    <TD STYLE="width: 47%; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>26-2540421</B></FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(State or other jurisdiction of<BR>
incorporation or organization)</FONT></TD>
    <TD>&#8239;</TD>
    <TD>&#8239;</TD>
    <TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(I.R.S. Employer <BR>
Identification Number)</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="text-align: center">&#8239;</TD>
    <TD>&#8239;</TD>
    <TD>&#8239;</TD>
    <TD STYLE="text-align: center">&#8239;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD COLSPAN="4" STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; background-color: white"><B>101 Lindenwood Drive,&#8239;Suite&#8239;225<BR>
Malvern,&#8239;PA&#8239;19355</B></FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD COLSPAN="4" STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(Address of principal executive offices, Zip Code)</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Annovis Bio,&#8239;Inc. Amended and Restated
2019 Equity Incentive Plan</B>&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center">(Full title of the plan)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Maria Maccecchini, Ph.D.<BR>
President and Chief Executive Officer<BR>
Annovis Bio,&#8239;Inc.<BR>
<FONT STYLE="background-color: white">101 Lindenwood Drive,&#8239;Suite&#8239;225<BR>
Malvern,&#8239;PA&#8239;19355</FONT></B>&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">(Name and address of agent for service)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center; background-color: white"><B>(484)&#8239;875-3192</B>&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt; text-align: center">(Telephone number, including
area code, of agent for service)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B><I>Copies to:</I></B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 50%; border: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Mitchell S. Nussbaum,&#8239;Esq.</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Janeanne Ferrari, Esq.</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Loeb&#8239;&amp; Loeb LLP</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>345 Park Avenue</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>New York, NY 10154</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>(212) 407-4000</B></P></TD>
    <TD STYLE="width: 50%; border-top: Black 1pt solid; border-right: Black 1pt solid; border-bottom: Black 1pt solid; padding-right: 5.4pt; padding-left: 5.4pt">
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Joan Guilfoyle,&#8239;Esq.<BR>
    Loeb&#8239;&amp; Loeb LLP<BR>
    901 New York Avenue NW<BR>
    Suite&#8239;300 East</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Washington, DC 20001<BR>
    (202) 618-5000</B></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&#8239;</P></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">Indicate by check mark whether the registrant
is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting company or an emerging growth company.
See definitions of &ldquo;large accelerated filer,&rdquo; &ldquo;accelerated filer,&rdquo; &ldquo;smaller reporting company,&rdquo; and
 &ldquo;emerging growth company&rdquo; in Rule&#8239;12b-2 of the Exchange Act.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 18%; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; color: Black">Large
    accelerated filer</FONT></TD>
    <TD STYLE="width: 2%; text-align: right"><FONT STYLE="font-family: Wingdings; color: Black"><FONT STYLE="font-family: Wingdings">&#168;</FONT></FONT></TD>
    <TD STYLE="width: 28%">&#8239;</TD>
    <TD STYLE="width: 20%; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; color: Black">Accelerated
    filer</FONT></TD>
    <TD STYLE="width: 8%; text-align: right"><FONT STYLE="font-family: Wingdings; font-size: 10pt; color: Black"><FONT STYLE="font-family: Wingdings">&#168;</FONT></FONT></TD>
    <TD STYLE="width: 22%">&#8239;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="text-align: justify">&#8239;</TD>
    <TD STYLE="text-align: right">&#8239;</TD>
    <TD>&#8239;</TD>
    <TD STYLE="text-align: justify">&#8239;</TD>
    <TD STYLE="text-align: right">&#8239;</TD>
    <TD>&#8239;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; color: Black">Non-accelerated
    filer</FONT></TD>
    <TD STYLE="text-align: justify">&#8239;<FONT STYLE="font-family: Wingdings">&#120;</FONT></TD>
    <TD>&#8239;</TD>
    <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; color: Black">Smaller
    reporting company </FONT></TD>
    <TD STYLE="text-align: right"> <FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; color: Black"><FONT STYLE="font-family: Wingdings">&#120;</FONT></FONT></TD>
    <TD>&#8239;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="text-align: justify">&nbsp;</TD>
    <TD STYLE="text-align: justify">&nbsp;</TD>
    <TD>&nbsp;</TD>
    <TD STYLE="text-align: justify">&nbsp;</TD>
    <TD STYLE="text-align: right">&nbsp;</TD>
    <TD>&nbsp;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD><FONT STYLE="color: Black">&#8239;</FONT></TD>
    <TD><FONT STYLE="color: Black">&#8239;</FONT></TD>
    <TD>&#8239;</TD>
    <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; color: Black">Emerging
    growth company </FONT></TD>
    <TD STYLE="text-align: right">&#8239;&#8239;&#8239;&#8239; <FONT STYLE="font-family: Wingdings">&#120;</FONT></TD>
    <TD>&#8239;</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; color: Black">If
an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying
with any new or revised financial accounting standards provided to Section&#8239;7(a)(2)(B)&#8239;of the Securities Act. </FONT><FONT STYLE="font-family: Wingdings; color: Black"><FONT STYLE="font-family: Wingdings"><FONT STYLE="font-family: Wingdings">&#168;</FONT></FONT></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<!-- Field: Rule-Page --><DIV STYLE="margin-top: 3pt; margin-bottom: 12pt; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 1pt solid; border-bottom: Black 2pt solid">&#8239;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<!-- Field: Page; Sequence: 1 -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1pt solid"><P STYLE="margin: 0pt">&#8239;</P></DIV>
    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&#8239;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>EXPLANATORY NOTE</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">This Registration Statement is being filed by
Annovis Bio, Inc. (the &ldquo;Company&rdquo;) pursuant to General Instruction E of Form S-8 under the Securities Act to register an additional
1,000,000 shares of the Company&rsquo;s common stock, par value $0.0001 per share (the &ldquo;Common Stock&rdquo;), for issuance in connection
with awards under the pursuant to the Amended and Restated 2019 Equity Incentive Plan (the &ldquo;Amended Plan&rdquo;). The Amended Plan
was approved by the Company&rsquo;s stockholders on June 12, 2024. The Amendment increases the number of shares of Common Stock authorized
for issuance under the Amended Plan from 2,000,000 shares to 3,000,000 shares (an increase of 1,000,000 shares).</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">Except as set forth below, the contents of the
Company&rsquo;s registration statement on Form S-8 (File No. 333-236457) filed with the U.S. Securities and Exchange Commission (the &ldquo;SEC&rdquo;)
on February 14, 2020 and relating to shares of Common Stock issuable in connection with awards under the 2019 Plan prior to the Amendment
are incorporated by reference herein as permitted by General Instruction E of Form S-8.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>PART&#8239;I</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>INFORMATION REQUIRED IN THE SECTION&#8239;10(a)&#8239;PROSPECTUS</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">The information specified in Item&#8239;1 and Item&#8239;2
of Part&#8239;I of Form&#8239;S-8&#8239;is omitted from this Registration Statement on Form&#8239;S-8&#8239;(the &ldquo;Registration Statement&rdquo;)
in accordance with the provisions of Rule&#8239;428 under the Securities Act of 1933, as amended (the &ldquo;Securities Act&rdquo;), and
the introductory note to Part&#8239;I of Form&#8239;S-8.&#8239;The documents containing the information specified in Part&#8239;I of Form&#8239;S-8&#8239;will
be delivered to the participants in the respective plans. Such documents are not required to be, and are not, filed with the Securities
and Exchange Commission (the &ldquo;Commission&rdquo;) either as part of this Registration Statement or as a prospectus or prospectus
supplement pursuant to Rule&#8239;424 under the Securities Act.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>PART&#8239;II</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>INFORMATION REQUIRED IN THE REGISTRATION STATEMENT</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 72px"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Item&#8239;3.</B></FONT></TD>
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Incorporation of Documents by Reference. </B></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">The following documents filed with the Commission
pursuant to the Securities Exchange Act of 1934, as amended (the &ldquo;Exchange Act&rdquo;), are incorporated into this Registration
Statement by reference:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/1477845/000155837024004393/anvs-20231231x10k.htm" STYLE="-sec-extract: exhibit">(a)</a>&#8239;&#8239;&#8239;&#8239;&#8239;&#8239;</FONT><A HREF="https://www.sec.gov/ix?doc=/Archives/edgar/data/1477845/000155837024004393/anvs-20231231x10k.htm" STYLE="-sec-extract: exhibit">The
Registrant&rsquo;s Annual Report on Form&#8239;10-K for the fiscal year ended December&#8239;31, 2023 as filed with the Securities and Exchange Commission on March&#8239;29, 2024</A>;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in">(b)&#8239;&#8239;&#8239;&#8239;&#8239;&#8239;All
other reports filed pursuant to Section&#8239;13(a)&#8239;or 15(d)&#8239;of the Exchange Act since December&#8239;31, 2023; and</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="text-align: justify; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-indent: 0.5in"><A HREF="https://www.sec.gov/Archives/edgar/data/1477845/000110465921140386/tm2133159d1_8a12b.htm" STYLE="-sec-extract: exhibit">(c)</a>&#8239;&#8239;&#8239;&#8239;&#8239;&#8239;&#8239;<A HREF="https://www.sec.gov/Archives/edgar/data/1477845/000110465921140386/tm2133159d1_8a12b.htm" STYLE="-sec-extract: exhibit">The
description of the Registrant&rsquo;s Common Stock contained in the Company&rsquo;s Registration Statement on&#8239;Form&#8239;8-A&#8239;(File&#8239;No.&#8239;001-39202)&#8239;filed with the Commission on November&#8239;17, 2021, pursuant to Section&#8239;12(b)&#8239;of the Exchange Act, including any amendment or report
filed for the purpose of updating such description.</A></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; background-color: white">In addition, all documents
filed by the Registrant pursuant to Sections 13(a), 13(c), 14 or 15(d)&#8239;of the Exchange Act after the date hereof, but prior to the
filing of a post-effective amendment to this Registration Statement that indicates that all securities offered hereby have been sold or
that deregisters all such securities then remaining unsold, shall be deemed to be incorporated by reference in this Registration Statement
and to be a part hereof from the date of filing of such documents. Notwithstanding the foregoing, unless specifically stated to the contrary
in such filing, none of the information that the Registrant discloses under Items 2.02 or 7.01 of any Current Report on Form&#8239;8-K&#8239;that
it may from time to time furnish to the Commission will be incorporated by reference into, or otherwise be included in or deemed to be
a part of, this Registration Statement.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; background-color: white">For purposes of this
Registration Statement, any document or any statement contained in a document incorporated or deemed to be incorporated herein by reference
shall be deemed to be modified or superseded to the extent that a subsequently filed document or a statement contained herein or in any
other subsequently filed document that also is or is deemed to be incorporated herein by reference modifies or supersedes such document
or such statement in such document. Any statement so modified or superseded shall not be deemed, except as so modified or superseded,
to constitute a part of this Registration Statement. Subject to the foregoing, all information in this Registration Statement is so qualified
in its entirety by the information appearing in the documents incorporated herein by reference.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 72px"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Item 4.</B></FONT></TD>
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Description of Securities.</B></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Not applicable.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 72px"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Item 5.</B></FONT></TD>
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Interests of Named Experts and Counsel.</B></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Not applicable.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<!-- Field: Page; Sequence: 2 -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1pt solid"><P STYLE="margin: 0pt">&#8239;</P></DIV>
    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&#8239;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 72px"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Item 6.</B></FONT></TD>
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Indemnification of Directors and Officers.</B></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">Section&#8239;102 of the General Corporation Law
of the State of Delaware permits a corporation to eliminate the personal liability of directors of a corporation to the corporation or
its stockholders for monetary damages for a breach of fiduciary duty as a director, except where the director breached his or her duty
of loyalty, failed to act in good faith, engaged in intentional misconduct or knowingly violated a law, authorized the payment of a dividend
or approved a stock repurchase in violation of Delaware corporate law or obtained an improper personal benefit. Our restated certificate
of incorporation provides that no director of the Registrant shall be personally liable to it or its stockholders for monetary damages
for any breach of fiduciary duty as a director, notwithstanding any provision of law imposing such liability, except to the extent that
the General Corporation Law of the State of Delaware prohibits the elimination or limitation of liability of directors for breaches of
fiduciary duty.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">Section&#8239;145 of the General Corporation Law
of the State of Delaware provides that a corporation has the power to indemnify a director, officer, employee, or agent of the corporation,
or a person serving at the request of the corporation for another corporation, partnership, joint venture, trust or other enterprise in
related capacities against expenses (including attorneys' fees), judgments, fines and amounts paid in settlement actually and reasonably
incurred by the person in connection with an action, suit or proceeding to which he or she was or is a party or is threatened to be made
a party to any threatened, ending or completed action, suit or proceeding by reason of such position, if such person acted in good faith
and in a manner he or she reasonably believed to be in or not opposed to the best interests of the corporation, and, in any criminal action
or proceeding, had no reasonable cause to believe his or her conduct was unlawful, except that, in the case of actions brought by or in
the right of the corporation, no indemnification shall be made with respect to any claim, issue or matter as to which such person shall
have been adjudged to be liable to the corporation unless and only to the extent that the Court of Chancery or other adjudicating court
determines that, despite the adjudication of liability but in view of all of the circumstances of the case, such person is fairly and
reasonably entitled to indemnity for such expenses which the Court of Chancery or such other court shall deem proper.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<!-- Field: Page; Sequence: 3 -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1pt solid"><P STYLE="margin: 0pt">&#8239;</P></DIV>
    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&#8239;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">Our restated certificate of incorporation provides
that we will indemnify each person who was or is a party or threatened to be made a party to any threatened, pending or completed action,
suit or proceeding (other than an action by or in the right of us) by reason of the fact that he or she is or was, or has agreed to become,
a director or officer, or is or was serving, or has agreed to serve, at our request as a director, officer, partner, employee or trustee
of, or in a similar capacity with, another corporation, partnership, joint venture, trust or other enterprise (all such persons being
referred to as an &quot;Indemnitee&quot;), or by reason of any action alleged to have been taken or omitted in such capacity, against
all expenses (including attorneys' fees), judgments, fines and amounts paid in settlement actually and reasonably incurred in connection
with such action, suit or proceeding and any appeal therefrom, if such Indemnitee acted in good faith and in a manner he or she reasonably
believed to be in, or not opposed to, our best interests, and, with respect to any criminal action or proceeding, he or she had no reasonable
cause to believe his or her conduct was unlawful. Our restated certificate of incorporation provides that we will indemnify any Indemnitee
who was or is a party to an action or suit by or in the right of us to procure a judgment in our favor by reason of the fact that the
Indemnitee is or was, or has agreed to become, a director or officer, or is or was serving, or has agreed to serve, at our request as
a director, officer, partner, employee or trustee of, or in a similar capacity with, another corporation, partnership, joint venture,
trust or other enterprise, or by reason of any action alleged to have been taken or omitted in such capacity, against all expenses (including
attorneys' fees) and, to the extent permitted by law, amounts paid in settlement actually and reasonably incurred in connection with such
action, suit or proceeding, and any appeal therefrom, if the Indemnitee acted in good faith and in a manner he or she reasonably believed
to be in, or not opposed to, our best interests, except that no indemnification shall be made with respect to any claim, issue or matter
as to which such person shall have been adjudged to be liable to us, unless a court determines that, despite such adjudication but in
view of all of the circumstances, he or she is entitled to indemnification of such expenses. Notwithstanding the foregoing, to the extent
that any Indemnitee has been successful, on the merits or otherwise, he or she will be indemnified by us against all expenses (including
attorneys' fees) actually and reasonably incurred in connection therewith. Expenses must be advanced to an Indemnitee under certain circumstances.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">We have entered into indemnification agreements
with each of our directors and officers. These indemnification agreements may require us, among other things, to indemnify our directors
and officers for some expenses, including attorneys' fees, judgments, fines and settlement amounts incurred by a director or officer in
any action or proceeding arising out of his or her service as one of our directors or officers, or any of our subsidiaries or any other
company or enterprise to which the person provides services at our request.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">We maintain a general liability insurance policy
that covers certain liabilities of directors and officers of our corporation arising out of claims based on acts or omissions in their
capacities as directors or officers.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<!-- Field: Page; Sequence: 4 -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1pt solid"><P STYLE="margin: 0pt">&#8239;</P></DIV>
    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&#8239;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 72px"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Item 7.</B></FONT></TD>
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Exemption from Registration Claimed.</B></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Not applicable.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 72px"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Item&#8239;8.</B></FONT></TD>
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Exhibits. </B></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">The following Exhibits are filed as part of this Registration Statement:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR>
<TD STYLE="vertical-align: top; width: 96px; border-bottom: black 1pt solid; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Exhibit&#8239;<BR>
No.</B></FONT></TD>
<TD STYLE="vertical-align: top; width: 12px; padding-left: 6.75pt; text-align: center">&#8239;</TD>
<TD STYLE="vertical-align: bottom; border-bottom: black 1pt solid; padding-left: 6.75pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Description</B></FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">4.1</FONT></TD>
<TD STYLE="padding-left: 6.75pt">&#8239;</TD>
<TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><A HREF="https://www.sec.gov/Archives/edgar/data/1477845/000110465920011925/tm206971d1_ex3-1.htm" STYLE="-sec-extract: exhibit">Amended
and Restated Certificate of Incorporation of the Registrant. (Incorporated by reference to Exhibit&#8239;3.1 to the Current Report filed
February&#8239;6, 2020)</A> as amended by <A HREF="https://www.sec.gov/Archives/edgar/data/1477845/000110465923072250/tm2318997d1_ex3-1.htm" STYLE="-sec-extract: exhibit">Certificate
of Amendment to Amended and Restated Certificate of Incorporation (incorporated by reference to Exhibit&#8239;3.1 to the Current Report
on Form&#8239;8-K filed June&#8239;16, 2023.)</A></FONT></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="text-align: center">&#8239;</TD>
<TD STYLE="padding-left: 6.75pt">&#8239;</TD>
<TD STYLE="text-align: justify">&#8239;</TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">4.2</FONT></TD>
<TD STYLE="padding-left: 6.75pt">&#8239;</TD>
<TD STYLE="text-align: justify"><A HREF="https://www.sec.gov/Archives/edgar/data/1477845/000110465920011925/tm206971d1_ex3-2.htm" STYLE="-sec-extract: exhibit">Amended and Restated Bylaws of the Registrant. (Incorporated by reference to Exhibit&#8239;3.2 to the Current Report filed February&#8239;6, 2020)</A></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="text-align: center">&nbsp;</TD>
<TD STYLE="padding-left: 6.75pt">&nbsp;</TD>
<TD STYLE="text-align: justify">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">4.3</FONT></TD>
<TD STYLE="padding-left: 6.75pt">&#8239;</TD>
<TD STYLE="text-align: justify"><A HREF="https://www.sec.gov/Archives/edgar/data/1477845/000110465924054167/tm243000d1_def14a.htm" STYLE="-sec-extract: exhibit"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Annovis Bio,&#8239;Inc. Amended and Restated 2019 Equity Incentive Plan. (incorporated by reference as Annex A to Definitive Proxy Statement on Schedule 14A filed April&#8239;29, 2024.)</FONT></A></TD></TR>
<TR STYLE="vertical-align: top">
<TD STYLE="text-align: center">&#8239;</TD>
<TD STYLE="padding-left: 6.75pt">&#8239;</TD>
<TD STYLE="text-align: justify">&#8239;</TD></TR>
<TR>
<TD STYLE="vertical-align: top; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">5.1*</FONT></TD>
<TD STYLE="vertical-align: top; padding-left: 6.75pt">&#8239;</TD>
<TD STYLE="text-align: justify"><A HREF="tm2417417d1_ex5-1.htm" STYLE="-sec-extract: exhibit"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Opinion
of Loeb&#8239;&amp; Loeb LLP regarding the legality of the securities being registered</FONT></A></TD></TR>
</TABLE>

<P STYLE="margin: 0">&#8239;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR>
<TD STYLE="vertical-align: top; text-align: center; width: 96px"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; color: Black">23.1*</FONT></TD>
<TD STYLE="vertical-align: top; padding-left: 6.75pt; width: 12px"><FONT STYLE="color: Black">&#8239;</FONT></TD>
<TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; color: Black"><A HREF="tm2417417d1_ex23-1.htm">Consent of Ernst&#8239;&amp; Young LLP</A></FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top; text-align: center"><FONT STYLE="color: Black">&#8239;</FONT></TD>
<TD STYLE="vertical-align: top; padding-left: 6.75pt"><FONT STYLE="color: Black">&#8239;</FONT></TD>
<TD STYLE="text-align: justify"><FONT STYLE="color: Black">&#8239;</FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; color: Black">23.2*</FONT></TD>
<TD STYLE="vertical-align: top; padding-left: 6.75pt"><FONT STYLE="color: Black">&#8239;</FONT></TD>
<TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt; color: Black"><A HREF="tm2417417d1_ex23-2.htm">Consent of WithumSmith+Brown,</A> </FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top; text-align: center"><FONT STYLE="color: Black">&#8239;</FONT></TD>
<TD STYLE="vertical-align: top; padding-left: 6.75pt"><FONT STYLE="color: Black">&#8239;</FONT></TD>
<TD><FONT STYLE="color: Black">&#8239;</FONT></TD></TR>
<TR>
<TD STYLE="vertical-align: top; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">23.3*</FONT></TD>
<TD STYLE="vertical-align: top; padding-left: 6.75pt"><FONT STYLE="color: Black">&#8239;</FONT></TD>
<TD><A HREF="tm2417417d1_ex5-1.htm"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Consent of Loeb&#8239;&amp; Loeb LLP (included in Exhibit&#8239;5.1)</FONT></A></TD></TR>
<TR>
<TD STYLE="vertical-align: top; text-align: center">&#8239;</TD>
<TD STYLE="vertical-align: top; padding-left: 6.75pt">&#8239;</TD>
<TD>&#8239;</TD></TR>
<TR>
<TD STYLE="vertical-align: top; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">107*</FONT></TD>
<TD STYLE="vertical-align: top; padding-left: 6.75pt">&#8239;</TD>
<TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><A HREF="tm2417417d1_ex-filingfees.htm">Fee Rate Table</A></FONT></TD></TR>
</TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<!-- Field: Rule-Page --><DIV STYLE="margin-top: 3pt; margin-bottom: 3pt; width: 100%"><DIV STYLE="font-size: 1pt; border-top: Black 1pt solid">&#8239;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">* Filed herewith.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 72px"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Item&#8239;9.</B></FONT></TD>
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Undertakings. </B></FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; background-color: white">(a)&#8239;&#8239;&#8239;&#8239;&#8239;&#8239;&#8239;The
undersigned Registrant hereby undertakes:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in; background-color: white">(1)&#8239;&#8239;&#8239;&#8239;&#8239;&#8239;&#8239;&#8239;To
file, during any period in which offers or sales are being made, a post-effective amendment to this Registration Statement:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 1in; background-color: white">(i)&#8239;&#8239;&#8239;&#8239;To
include any prospectus required by Section&#8239;10(a)(3)&#8239;of the Securities Act;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 1in; background-color: white">(ii)&#8239;&#8239;&#8239;To
reflect in the prospectus any facts or events arising after the effective date of the Registration Statement (or the most recent post-effective
amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in the Registration
Statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of securities
offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range
may be reflected in the form of prospectus filed with the Commission pursuant to Rule&#8239;424(b)&#8239;if, in the aggregate, the changes
in volume and price represent no more than a 20% change in the maximum aggregate offering price set forth in the &ldquo;Calculation of
Registration Fee&rdquo; table in the effective Registration Statement;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 1in; background-color: white">(iii)&#8239;To
include any material information with respect to the plan of distribution not previously disclosed in the Registration Statement or any
material change to such information in the Registration Statement.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; background-color: white"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><I>provided,
however,</I></FONT>&#8239;that paragraphs (a)(1)(i)&#8239;and (a)(1)(ii)&#8239;do not apply if the information required to be included in
a post-effective amendment by those paragraphs is contained in reports filed with or furnished to the Commission by the Registrant pursuant
to Section&#8239;13 or Section&#8239;15(d)&#8239;of the Exchange Act that are incorporated by reference in the Registration Statement.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in; background-color: white">(2)&#8239;&#8239;&#8239;&#8239;&#8239;&#8239;&#8239;&#8239;That,
for the purpose of determining any liability under the Securities Act, each such post-effective amendment shall be deemed to be a new
Registration Statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to
be the initial&#8239;<I>bona fide</I>&#8239;offering thereof.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<!-- Field: Page; Sequence: 5 -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1pt solid"><P STYLE="margin: 0pt">&#8239;</P></DIV>
    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&#8239;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in; background-color: white">(3)&#8239;&#8239;&#8239;&#8239;&#8239;&#8239;&#8239;&#8239;&#8239;To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold
at the termination of the offering.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; background-color: white">(b)&#8239;&#8239;&#8239;&#8239;&#8239;&#8239;The
undersigned Registrant hereby undertakes that, for purposes of determining any liability under the Securities Act, each filing of the
Registrant&rsquo;s annual report pursuant to Section&#8239;13(a)&#8239;or Section&#8239;15(d)&#8239;of the Exchange Act <FONT STYLE="background-color: white">(and,
where applicable, each filing of an employee benefit plan&rsquo;s annual report pursuant to Section&#8239;15(d)&#8239;of the Exchange Act)&#8239;
</FONT>that is incorporated by reference in the Registration Statement shall be deemed to be a new Registration Statement relating to
the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial&#8239;<I>bona fide</I>&#8239;offering
thereof.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; background-color: white"><FONT STYLE="background-color: white">(c)&#8239;&#8239;&#8239;&#8239;&#8239;&#8239;&#8239;Insofar
as indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of
the Registrant pursuant to the foregoing provisions, or otherwise, the Registrant has been advised that in the opinion of the Commission
such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable. In the event that a
claim for indemnification against such liabilities (other than the payment by the Registrant of expenses incurred or paid by a director,
officer or controlling person of the registrant in the successful defense of any action, suit or proceeding) is asserted by such director,
officer or controlling person in connection with the securities being registered, the registrant will, unless in the opinion of its counsel
the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification
by it is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.</FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<!-- Field: Page; Sequence: 6 -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1pt solid"><P STYLE="margin: 0pt">&#8239;</P></DIV>
    <DIV STYLE="break-before: page; margin-top: 6pt; margin-bottom: 12pt"><P STYLE="margin: 0pt">&#8239;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>SIGNATURES</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">Pursuant to the requirements
of the Securities Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements
for filing on Form&#8239;S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the Borough of Malvern, Commonwealth of Pennsylvania, on June&#8239;21, 2024.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD>&#8239;</TD>
    <TD COLSPAN="3"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>ANNOVIS BIO,&#8239;INC.</B></FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD>&#8239;</TD>
    <TD COLSPAN="3">&#8239;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD>&#8239;</TD>
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">By:</FONT></TD>
    <TD COLSPAN="2" STYLE="border-bottom: black 1pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/&#8239;Maria Maccecchini</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 50%">&#8239;</TD>
    <TD STYLE="width: 3%">&#8239;</TD>
    <TD STYLE="width: 5%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Name:</FONT></TD>
    <TD STYLE="width: 42%"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Maria Maccecchini</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD>&#8239;</TD>
    <TD>&#8239;</TD>
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Title:</FONT></TD>
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Chief Executive Officer</FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify; text-indent: 0.5in">Pursuant to the requirements
of the Securities Act of 1933, this Registration Statement has been signed by the following persons in the capacities and on the date
indicated.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="text-align: center; width: 28%; border-bottom: black 1pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Signature</B></FONT></TD>
    <TD STYLE="text-align: center; width: 1%">&#8239;</TD>
    <TD STYLE="text-align: center; width: 48%; border-bottom: black 1pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Title</B></FONT></TD>
    <TD STYLE="text-align: center; width: 3%">&#8239;</TD>
    <TD STYLE="border-bottom: black 1pt solid; width: 20%; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Date</B></FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD>&#8239;</TD>
    <TD>&#8239;</TD>
    <TD>&#8239;</TD>
    <TD>&#8239;</TD>
    <TD STYLE="text-align: justify">&#8239;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: bottom; border-bottom: black 1pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/&#8239;Maria Maccecchini</FONT></TD>
    <TD STYLE="vertical-align: top">&#8239;</TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">President and Chief Executive Officer</FONT></TD>
    <TD STYLE="vertical-align: top">&#8239;</TD>
    <TD STYLE="vertical-align: top; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">June&#8239;21, 2024</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Maria Maccecchini</FONT></TD>
    <TD>&#8239;</TD>
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">(Principal Executive Officer&#8239;&amp; Interim Principal Financial Officer)</FONT></TD>
    <TD>&#8239;</TD>
    <TD STYLE="text-align: justify">&#8239;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD>&#8239;</TD>
    <TD>&#8239;</TD>
    <TD>&#8239;</TD>
    <TD>&#8239;</TD>
    <TD STYLE="text-align: justify">&#8239;</TD></TR>
  <TR>
    <TD STYLE="vertical-align: bottom; border-bottom: black 1pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/&#8239;Michael Hoffman</FONT></TD>
    <TD STYLE="vertical-align: top">&#8239;</TD>
    <TD STYLE="vertical-align: top"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Chairman of the Board and Director</FONT></TD>
    <TD STYLE="vertical-align: top">&#8239;</TD>
    <TD STYLE="vertical-align: top; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">June&#8239;21, 2024</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Michael Hoffman</FONT></TD>
    <TD>&#8239;</TD>
    <TD>&#8239;</TD>
    <TD>&#8239;</TD>
    <TD STYLE="text-align: justify">&#8239;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD>&#8239;</TD>
    <TD>&#8239;</TD>
    <TD>&#8239;</TD>
    <TD>&#8239;</TD>
    <TD STYLE="text-align: justify">&#8239;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="border-bottom: black 1pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/&#8239;Claudine Bruck</FONT></TD>
    <TD>&#8239;</TD>
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director</FONT></TD>
    <TD>&#8239;</TD>
    <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">June&#8239;21, 2024</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Claudine Bruck</FONT></TD>
    <TD>&#8239;</TD>
    <TD>&#8239;</TD>
    <TD>&#8239;</TD>
    <TD STYLE="text-align: justify">&#8239;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD>&#8239;</TD>
    <TD>&#8239;</TD>
    <TD>&#8239;</TD>
    <TD>&#8239;</TD>
    <TD STYLE="text-align: justify">&#8239;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="border-bottom: black 1pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/&#8239;Reid McCarthy</FONT></TD>
    <TD>&#8239;</TD>
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director</FONT></TD>
    <TD>&#8239;</TD>
    <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">June&#8239;21, 2024</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Reid McCarthy</FONT></TD>
    <TD>&#8239;</TD>
    <TD>&#8239;</TD>
    <TD>&#8239;</TD>
    <TD STYLE="text-align: justify">&#8239;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD>&#8239;</TD>
    <TD>&#8239;</TD>
    <TD>&#8239;</TD>
    <TD>&#8239;</TD>
    <TD STYLE="text-align: justify">&#8239;</TD></TR>
  <TR STYLE="vertical-align: top">
    <TD STYLE="border-bottom: black 1pt solid"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">/s/&#8239;Mark White</FONT></TD>
    <TD>&#8239;</TD>
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Director</FONT></TD>
    <TD>&#8239;</TD>
    <TD STYLE="text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">June&#8239;21, 2024</FONT></TD></TR>
  <TR STYLE="vertical-align: top">
    <TD><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt">Mark White</FONT></TD>
    <TD>&#8239;</TD>
    <TD>&#8239;</TD>
    <TD>&#8239;</TD>
    <TD STYLE="text-align: justify">&#8239;</TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<!-- Field: Page; Sequence: 7; Options: Last -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1pt solid"><P STYLE="margin: 0pt">&#8239;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&#8239;</P>

</BODY>
</HTML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>2
<FILENAME>tm2417417d1_ex5-1.htm
<DESCRIPTION>EXHIBIT 5.1
<TEXT>
<HTML>
<HEAD>
     <TITLE></TITLE>
</HEAD>
<BODY STYLE="font: 10pt Times New Roman, Times, Serif">

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="text-align: right; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Exhibit 5.1</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
  <TR STYLE="vertical-align: top">
    <TD STYLE="width: 46%; font-size: 10pt"><IMG SRC="tm2417417d1_ex5-1img001.jpg" ALT=""></TD>
    <TD STYLE="width: 28%"><P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="font-variant: small-caps"><B>&nbsp;</B></FONT></P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>
    <P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">345 Park Avenue<BR>
    New York, NY 10154</P></TD>
    <TD STYLE="text-align: left; width: 26%; font-size: 10pt; vertical-align: middle"><FONT STYLE="font-family: Times New Roman, Times, Serif; font-size: 10pt"><B>Direct</B>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;212.407.4000<BR>
    <B>Main</B>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;212.407.4000<BR>
    <B>Fax</B>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;212.407.4000<BR>
    </FONT></TD></TR>
  </TABLE>
<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">June&nbsp;21, 2024</P>


<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt">Annovis Bio,&nbsp;Inc. <BR>
101 Lindenwood Drive; Suite&nbsp;225 <BR>
Malvern, PA 19355 &nbsp;</P>


<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Ladies and Gentlemen:</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">We have served as counsel to Annovis Bio,&nbsp;Inc.,
a Delaware corporation (the &ldquo;Company&rdquo;), in connection with the preparation of the Company&rsquo;s Registration Statement on
Form&nbsp;S-8 (the &ldquo;Registration Statement&rdquo;) to be filed with the Securities and Exchange Commission under the Securities
Act of 1933, as amended (the &ldquo;Act&rdquo;), registering the issuance of 1,000,000 shares of common stock, par value $0.0001 per share
(the &ldquo;2019 Plan Shares&rdquo;), of the Company issuable pursuant to the Annovis Bio,&nbsp;Inc. Amended and Restated 2019 Equity
Incentive Plan.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">We have examined originals or copies, certified
or otherwise identified to our satisfaction, of such corporate records of the Company and other certificates and documents of officials
of the Company, and others as we have deemed appropriate for purposes of this letter. We have assumed the genuineness of all signatures,
the authenticity of all documents submitted to us as originals, and the conformity to authentic original documents of all copies submitted
to us as conformed and certified or reproduced copies.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">Based upon the foregoing, it is our opinion that
the Shares, when issued and delivered pursuant to and in accordance with the terms of the 2019 Plan, and the awards granted under the
2019 Plan, will be validly issued, fully paid and non-assessable.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">We are furnishing this opinion in connection with
the filing of the Registration Statement, and this opinion is not to be relied upon for any other purpose without our prior written consent.
We consent to the reference made to our firm in the Registration Statement and to the filing of this opinion as an exhibit to the Registration
Statement. In giving this consent, we do not hereby admit that we are in the category of persons whose consent is required under Section&nbsp;7
of the Act, or the rules&nbsp;and regulations promulgated thereunder.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">Sincerely,</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><I>/s/ Loeb&nbsp;&amp; Loeb LLP</I></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Loeb&nbsp;&amp; Loeb LLP</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Los Angeles New York Chicago Nashville Washington, DC San Francisco Beijing Hong Kong www.loeb.com</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">For the United States offices, a limited
liability partnership including professional corporations. For Hong Kong office, a limited liability partnership.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<!-- Field: Page; Sequence: 1; Options: Last -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1pt solid"><P STYLE="font-size: 10pt; text-align: center; margin-top: 0pt; margin-bottom: 0pt">&nbsp;</P><P STYLE="font-size: 10pt; text-align: center; margin-top: 0pt; margin-bottom: 0pt"></P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

</BODY>
</HTML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>3
<FILENAME>tm2417417d1_ex23-1.htm
<DESCRIPTION>EXHIBIT 23.1
<TEXT>
<HTML>
<HEAD>
     <TITLE></TITLE>
</HEAD>
<BODY STYLE="font: 10pt Times New Roman, Times, Serif">

<P STYLE="margin: 0">&nbsp;</P>

<P STYLE="text-align: right; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Exhibit&nbsp;23.1</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Consent of Independent Registered Public Accounting
Firm</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">We consent to the incorporation by reference in the Registration Statement
(Form&nbsp;S-8) pertaining to the Amended and Restated 2019 Equity Incentive Plan of Annovis Bio,&nbsp;Inc. of our report dated March&nbsp;29,
2024, with respect to the consolidated financial statements of Annovis Bio,&nbsp;Inc. included in its Annual Report (Form&nbsp;10-K) for
the year ended December&nbsp;31, 2023, filed with the Securities and Exchange Commission.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">/s/ Ernst&nbsp;&amp; Young LLP</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">Philadelphia, Pennsylvania</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">June&nbsp;21, 2024</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<!-- Field: Page; Sequence: 1; Options: Last -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1pt solid"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="margin: 0"></P>

</BODY>
</HTML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.2
<SEQUENCE>4
<FILENAME>tm2417417d1_ex23-2.htm
<DESCRIPTION>EXHIBIT 23.2
<TEXT>
<HTML>
<HEAD>
     <TITLE></TITLE>
</HEAD>
<BODY STYLE="font: 10pt Times New Roman, Times, Serif">

<P STYLE="margin: 0">&nbsp;</P>

<P STYLE="text-align: right; font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><B>Exhibit&nbsp;23.2</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"><FONT STYLE="text-transform: uppercase"><B>CONSENT OF INDEPENDENT REGISTERED
PUBLIC ACCOUNTING FIRM</B></FONT></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">We hereby consent to the incorporation by reference
in this Registration Statement of our report dated March&nbsp;31, 2023 (which includes an explanatory paragraph relating to Annovis Bio,&nbsp;Inc&rsquo;s
ability to continue as a going concern), relating to the financial statements of Annovis Bio,&nbsp;Inc. as of and for the year ended December&nbsp;31,
2022, appearing in the entity&rsquo;s Annual Report on Form&nbsp;10-K for the year ended December&nbsp;31, 2023.</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">/s/ WithumSmith+Brown, PC</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">East Brunswick, New Jersey</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">June&nbsp;21, 2024</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="margin: 0"></P>

<!-- Field: Page; Sequence: 1; Options: Last -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1pt solid"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="margin: 0">&nbsp;</P>

</BODY>
</HTML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-FILING FEES
<SEQUENCE>5
<FILENAME>tm2417417d1_ex-filingfees.htm
<DESCRIPTION>EX-FILING FEES
<TEXT>
<HTML>
<HEAD>
     <TITLE></TITLE>
</HEAD>
<BODY STYLE="font: 10pt Times New Roman, Times, Serif">

<P STYLE="margin: 0">&nbsp;</P>

<P STYLE="text-align: right; margin: 0"><B>Exhibit 107</B></P>

<P STYLE="margin: 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Calculation of Filing Fee Table</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>FORM&nbsp;S-8</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>REGISTRATION STATEMENT UNDER THE SECURITIES
ACT OF 1933</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">(Form&nbsp;Type)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><B>Annovis Bio,&nbsp;Inc.</B></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center">(Exact Name of Registrant As Specified in its Charter)</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: center"><U>Table 1: Newly Registered Securities</U></P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="font: 10pt Times New Roman, Times, Serif; width: 100%; border-collapse: collapse">
<TR>
<TD STYLE="text-align: center">&nbsp;</TD>
<TD STYLE="text-align: center">&nbsp;</TD>
<TD STYLE="border-bottom: Black 1pt solid; vertical-align: bottom; text-align: center"><FONT STYLE="font-size: 10pt"><B>Security <BR>
Type</B></FONT></TD>
<TD STYLE="text-align: center">&nbsp;</TD>
<TD STYLE="text-align: center">&nbsp;</TD>
<TD STYLE="border-bottom: Black 1pt solid; vertical-align: bottom; text-align: center"><FONT STYLE="font-size: 10pt"><B>Security<BR>
 Class&nbsp;<BR>
Title</B></FONT></TD>
<TD STYLE="text-align: center">&nbsp;</TD>
<TD COLSPAN="2" STYLE="text-align: center; vertical-align: bottom; border-bottom: Black 1pt solid"><B>Fee<BR>
 Calculation</B> <B><BR>
Rule</B></TD>
<TD STYLE="text-align: center">&nbsp;</TD>
<TD STYLE="text-align: center">&nbsp;</TD>
<TD COLSPAN="2" STYLE="border-bottom: Black 1pt solid; vertical-align: bottom; text-align: center"><FONT STYLE="font-size: 10pt"><B>Amount<BR>
 Registered</B><SUP>(1)</SUP></FONT></TD>
<TD STYLE="text-align: center">&nbsp;</TD>
<TD STYLE="text-align: center">&nbsp;</TD>
<TD COLSPAN="2" STYLE="text-align: center; vertical-align: bottom; border-bottom: Black 1pt solid"><B>Proposed <BR>
Maximum</B> <B><BR>
Offering&nbsp;Price<BR>
</B> <B>Per&nbsp;Share</B></TD>
<TD STYLE="text-align: center">&nbsp;</TD>
<TD STYLE="text-align: center">&nbsp;</TD>
<TD COLSPAN="2" STYLE="text-align: center; vertical-align: bottom; border-bottom: Black 1pt solid"><B>Maximum<BR>
 Aggregate</B> <B><BR>
Offering</B> <B><BR>
Price</B></TD>
<TD STYLE="text-align: center">&nbsp;</TD>
<TD STYLE="text-align: center">&nbsp;</TD>
<TD COLSPAN="2" STYLE="border-bottom: Black 1pt solid; vertical-align: bottom; text-align: center"><FONT STYLE="font-size: 10pt"><B>Fee <BR>
Rate</B></FONT></TD>
<TD STYLE="text-align: center">&nbsp;</TD>
<TD STYLE="text-align: center">&nbsp;</TD>
<TD COLSPAN="2" STYLE="text-align: center; vertical-align: bottom; border-bottom: Black 1pt solid"><B>Amount <BR>
of <BR>
Registration<BR>
</B> <B>Fee</B></TD>
<TD STYLE="text-align: center">&nbsp;</TD></TR>
<TR>
<TD COLSPAN="29" STYLE="vertical-align: bottom; text-align: center"><FONT STYLE="font-size: 10pt"><B>Newly Registered Securities</B></FONT></TD>
<TD>&nbsp;</TD></TR>
<TR STYLE="background-color: #CCEEFF">
<TD STYLE="vertical-align: bottom; width: 5%"><FONT STYLE="font-size: 10pt"><B>Fees to Be Paid</B></FONT></TD>
<TD STYLE="width: 1%; text-align: center">&nbsp;</TD>
<TD STYLE="vertical-align: bottom; width: 8%; text-align: center"><FONT STYLE="font-size: 10pt">Equity</FONT></TD>
<TD STYLE="width: 1%">&nbsp;</TD>
<TD STYLE="width: 1%">&nbsp;</TD>
<TD STYLE="vertical-align: bottom; width: 8%; text-align: center"><FONT STYLE="font-size: 10pt">Common Stock, $0.0001 par value per share</FONT></TD>
<TD STYLE="width: 1%">&nbsp;</TD>
<TD STYLE="width: 1%">&nbsp;</TD>
<TD STYLE="vertical-align: bottom; width: 8%; text-align: center"><FONT STYLE="font-size: 10pt">457(c)&nbsp;and 457(h)</FONT></TD>
<TD STYLE="width: 1%">&nbsp;</TD>
<TD STYLE="width: 1%">&nbsp;</TD>
<TD STYLE="width: 1%">&nbsp;</TD>
<TD STYLE="vertical-align: bottom; width: 10%; text-align: right"><FONT STYLE="font-size: 10pt">1,000,000</FONT></TD>
<TD STYLE="vertical-align: bottom; width: 1%">&nbsp;</TD>
<TD STYLE="vertical-align: bottom; width: 1%"><FONT STYLE="font-size: 10pt">$</FONT></TD>
<TD STYLE="vertical-align: bottom; width: 1%">&nbsp;</TD>
<TD STYLE="vertical-align: bottom; width: 10%; text-align: right"><FONT STYLE="font-size: 10pt">5.58</FONT></TD>
<TD STYLE="vertical-align: bottom; width: 1%"><FONT STYLE="font-size: 10pt"><SUP>(2)</SUP>&nbsp;</FONT></TD>
<TD STYLE="width: 1%">&nbsp;</TD>
<TD STYLE="vertical-align: bottom; width: 1%"><FONT STYLE="font-size: 10pt">$</FONT></TD>
<TD STYLE="vertical-align: bottom; width: 10%; text-align: right"><FONT STYLE="font-size: 10pt">5,580,000</FONT></TD>
<TD STYLE="width: 1%">&nbsp;</TD>
<TD STYLE="width: 1%">&nbsp;</TD>
<TD STYLE="width: 1%">&nbsp;</TD>
<TD STYLE="vertical-align: bottom; width: 10%; text-align: right"><FONT STYLE="font-size: 10pt">0.0001476</FONT></TD>
<TD STYLE="width: 1%">&nbsp;</TD>
<TD STYLE="width: 1%">&nbsp;</TD>
<TD STYLE="vertical-align: bottom; width: 1%"><FONT STYLE="font-size: 10pt">$</FONT></TD>
<TD STYLE="vertical-align: bottom; width: 10%; text-align: right"><FONT STYLE="font-size: 10pt">823.61</FONT></TD>
<TD STYLE="width: 1%">&nbsp;</TD></TR>
<TR STYLE="background-color: white">
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD STYLE="text-align: center">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD STYLE="text-align: center">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD COLSPAN="9" STYLE="vertical-align: bottom; text-align: center"><FONT STYLE="font-size: 10pt"><B>Total Offering Amounts</B></FONT></TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD STYLE="vertical-align: bottom"><FONT STYLE="font-size: 10pt">$</FONT></TD>
<TD STYLE="vertical-align: bottom">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD STYLE="text-align: right">&nbsp;</TD>
<TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-size: 10pt">0.0001476</FONT></TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD STYLE="vertical-align: bottom"><FONT STYLE="font-size: 10pt">$</FONT></TD>
<TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-size: 10pt">823.61</FONT></TD>
<TD>&nbsp;</TD></TR>
<TR STYLE="background-color: #CCEEFF">
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD STYLE="text-align: center">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD STYLE="text-align: center">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD COLSPAN="9" STYLE="vertical-align: bottom; text-align: center"><FONT STYLE="font-size: 10pt"><B>Total Fees Previously Paid</B></FONT></TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD STYLE="vertical-align: bottom; text-align: right">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD STYLE="text-align: right">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-size: 10pt">0</FONT></TD>
<TD>&nbsp;</TD></TR>
<TR STYLE="background-color: white">
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD STYLE="text-align: center">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD STYLE="text-align: center">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD COLSPAN="9" STYLE="vertical-align: bottom; text-align: center"><FONT STYLE="font-size: 10pt"><B>Total Fee Offsets</B></FONT></TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD STYLE="vertical-align: bottom; text-align: right">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD STYLE="text-align: right">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-size: 10pt">0</FONT></TD>
<TD>&nbsp;</TD></TR>
<TR STYLE="background-color: #CCEEFF">
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD STYLE="text-align: center">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD STYLE="text-align: center">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD COLSPAN="9" STYLE="vertical-align: bottom; text-align: center"><FONT STYLE="font-size: 10pt"><B>Net Fees Due</B></FONT></TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD STYLE="text-align: right">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD STYLE="text-align: right">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD>&nbsp;</TD>
<TD STYLE="vertical-align: bottom; text-align: right"><FONT STYLE="font-size: 10pt">823.61</FONT></TD>
<TD>&nbsp;</TD></TR>
</TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0; text-align: justify">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 0.25in">(1)</TD><TD STYLE="text-align: justify">Pursuant to Rule&nbsp;416(c)&nbsp;under the Securities Act of 1933, as amended (the &ldquo;Securities
Act&rdquo;), this registration statement also covers an indeterminate amount of interests to be offered or sold pursuant to the registrant&rsquo;s
2019 Equity Incentive Plan (the &ldquo;Plan&rdquo;).</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" STYLE="width: 100%; font: 10pt Times New Roman, Times, Serif; margin-top: 0pt; margin-bottom: 0pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0%"></TD><TD STYLE="width: 0.25in">(2)</TD><TD STYLE="text-align: justify">Estimated solely for the purpose of calculating the registration fee pursuant to Rule&nbsp;457(c)&nbsp;and
Rule&nbsp;457(h)&nbsp;under the Securities Act based on the average of the high and low prices of the registrant&rsquo;s common stock
as reported by The New York Stock Exchange on June&nbsp;18, 2024.</TD></TR></TABLE>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0"></P>

<!-- Field: Page; Sequence: 1; Options: Last -->
    <DIV STYLE="margin-top: 12pt; margin-bottom: 6pt; border-bottom: Black 1pt solid"><P STYLE="margin: 0pt">&nbsp;</P></DIV>
    <!-- Field: /Page -->

<P STYLE="font: 10pt Times New Roman, Times, Serif; margin: 0pt 0">&nbsp;</P>

</BODY>
</HTML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>tm2417417d1_ex5-1img001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
begin 644 tm2417417d1_ex5-1img001.jpg
M_]C_X  02D9)1@ ! 0$ R #(  #_VP!#  $! 0$! 0$! 0$! 0$! 0$! 0$!
M 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0'_
MVP!# 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0$!
M 0$! 0$! 0$! 0$! 0$! 0$! 0$! 0'_P  1" "- (P# 2(  A$! Q$!_\0
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M ,)*7^1_/_\ K[QQ_P!%7F'_ (?^)O\ YWGVW_P\5_;$_P"BQ/\ ^$!\,?\
MYCZ/^'BO[8G_ $6)_P#P@/AC_P#,?7Q)11_J%P)_T265?^$E+_(/]?>./^BK
MS#_P_P#$W_SO/MO_ (>*_MB?]%B?_P (#X8__,?0?^"BG[8A!!^,3X88/_%
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M4A/[>?\ V>=^U%_ZN_QW7Q77O\/?\D[D7_8GP/\ ZBX0[\X_Y&^<?]C+%?\
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M99!@LTPV*J8-SJ3A"M2CB*490C.<):N:3Y5*6U]%V/\ /]_X*.?\I"?V\_\
ML\[]J+_U=_CNOBLLBY+LJ@*Y&YE4ML1G*KN(WN55MD:;I)& 6-68A3]J?\%'
M/^4A/[>?_9YW[47_ *N_QW7'?L0>']#\7?ME_LF>$O%.CZ9XC\*>*OVF_P!G
MWPWXI\-:S:Q7NE^(_#VM_&'P5INK:)?VEQ'+:W-G?VMP\5S#=Q26\L'F1NC%
ME!_H++<2\%POE.-=*=:.%R+"5Y0A%R<HT\'AI2TVTCS2;;2482DVHQDU^-XO
M"O&\1YAA%-4WB<WQ%)3DU%1<JU>UV]%=Q45W<DE=M)_+[1N@5F&P2()(MY"F
M6(RSP^9$I(,L:RVTJ/)&&2,^7O*B> R- R&.1\JL[9*C"(-TLAR1B."(/<7$
MGW+:UBGNIVCMH)I8_P!'/^"N/P^\%?"O_@H[^U?\//AQX.\+?#WP3X6\>Z59
M:+X+\$:%I7AOPIH2/X,\-7=S:Z/I.C6.FVD8\Z[^UW<KV@::XOV,,DF+@+^>
MVDVEW?ZCIEAIEE<:GJ5]J>F6=EI=I;R75QJ-S=ZA;6\5G#;6\4E]=S2O+_H]
MIIYAN[NX6*U6ZM89IKF+U,OSC"XG+H9Q7KULLP?U6EC?K5/#/$U:6'K13IUJ
M.'2E]9O*:IQ5-2C/]XX75.YSXO*:^"Q[P+YJE2G6C1K.-[TIRORQG[K]G*:5
MX*:O9IVU=L\1'GS!L56F1VD(C2-H'6.42M)M6((TD8W2%%(EB*DK+&6-BH6.
M-NS;O+XC4*[*D;%G"J5DD:..)L[999(HXRTDD:M_3)XV\)_L:_\ !%3X7?#K
MP!\9_P!F_P"%W[:G_!1;XD^#O#'Q%\9:;\7='E\0?!#X >'-7TN2/P_X2;1;
M_4?$>BZ[?Z7?Z=J-LDFAZ3I^N7\%Q)=QZOHG@]/#6C7/#?"__@J9^P!^TGKZ
M_"S]OG_@FS^RS\-OAQXM!\/Q?'+]F#X>K\/_ !O\,FU0)IUKK5[;Z5&?$ESX
M>M+BYWZN^E>+QY&E>?+/X>UF))=*N?D*W&N.J?6,5EW#>*SO!TI?[/G56-3"
MXF252$'6P67Q7/BY^SE5<:<$Y2@JLU!1IW/HI\+X9^PH2S#"TL76Y>:C.M3C
M5@I1<DYQE).&R3O&R;W/YU&7;YA<>28HFGF$Q$)MH4V;I;Q9=ALX]TL,:/<^
M4LDMQ;0H6EN(4D8I&[ P3F5"-ZKAH6"2J22 &1F7<A(;#H^-K*Q_I$_9K_X)
MF:7^R_\ \%S_ -GS]D3XXZ#X,^-_P<\4Q?$[QQX,NO&'A_1O%7@_XH_#:\^#
MOQBU7PG=:SX;U/3)- M-:\-:KH$L=_!I-GI=E:^-H[]K'2$T--/U"[V/VF?^
M"F'[,7[/G[2O[1/P6TS_ ()#_P#!/3Q)HWP@^,_Q!^%.G:YK7PRTBVOM?L/A
M_P",=0\(:3K.J01>'$!\17EK#;S:N+#[3:#SVDEF'V.<P:8CCN&+Q=/ 9'@*
MF:TL3EU+%T)X+%X?"PG6G65"4(XRNU2I58UZ>(HRYU&4*U&K0DHU%*$=,/P?
M["KBZ>8X^E@7@FXUXXFA5Q,J4O90KQ4L#12Q%5NA5I552A^\E2J1K17LTY/^
M:M('?! C!+*!F>/EF8*H'SG)9F4 #.2:<XFMRA8*AF#^26*D3(@B9Y(=V!+$
MOG0AIH]T:LX0L'RH_7O]H[_@II\%/CO\$?'7PL\(_P#!,K]BC]GW7?%L&D6N
MG_&3X0>$)_#GQ#\#S:/X@T+Q+-?^&M9TK2M+N[:]NK337TYA%?PK-;WMS$WF
M!)D7],?C!\<?V7OV"OV%/^"8'B<?\$VOV,?CWXV_:7_9[U;Q=X\\3?%+X9>%
MH_$<^M>";3X?02:K>7UCHMQ?>(+O5I/&LK7&LZG/?7$C6P;[5LN8_-O&\3YI
MEU;+<NQ?"6;4,1FU7ZO07^M>2JK.?LJM;]TU*_,XT9\KNFVI15VU%X87AO*,
M<L;6H\4956^I0=26'GD.<T(5%S1BHU)J+5*+<KMR>G+'9R5_Y5D-Y*56.%IW
M8@)'#&LDK,6"C;'&&D;!.6VJ0J[G;"*S" /)<^4HBD!F#R0CRFW3",LDAB7
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M]^K6^ED23_Z\_P"ZW_HIZ_T!_P#@U._Y1Y?&7_L]'XD_^J7_ &>Z_P _B?\
MUY_W6_\ 13U_H#_\&IW_ "CR^,O_ &>C\2?_ %2_[/=?(^,/_)"UO^RNP_\
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M*$.6M^[I\N[YW*T5#W%>^ETC]EO'GPG_ &(/^"/'PK^&>C?M*?L[^'/VT?\
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M]>NO$,OQ6_9^\)?'"]\[0[73Y/#>H^*M0\2Z==Z CVMZ1FW7PE=2PWEVINY
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@F>Y/GN$J5OJO[W(L2FU.G/E<J].2@URZO2[EM;3<_]D!

end
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
