    <SEC-DOCUMENT>0001104659-25-043574-index.html : 20250501
    <SEC-HEADER>0001104659-25-043574.hdr.sgml : 20250501
    <ACCEPTANCE-DATETIME>20250501172049
    ACCESSION NUMBER:		0001104659-25-043574
    CONFORMED SUBMISSION TYPE:	ARS
    PUBLIC DOCUMENT COUNT:		1
    CONFORMED PERIOD OF REPORT:	20241231
    FILED AS OF DATE:		20250501
    DATE AS OF CHANGE:		20250501
    EFFECTIVENESS DATE:		20250501

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Annovis Bio, Inc.
    		CENTRAL INDEX KEY:			0001477845
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		ORGANIZATION NAME:           	03 Life Sciences
    		EIN:				262540421
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		ARS
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-39202
    		FILM NUMBER:		25904420

    	BUSINESS ADDRESS:
    		STREET 1:		101 LINDENWOOD DRIVE, SUITE 225
    		CITY:			MALVERN
    		STATE:			PA
    		ZIP:			19355
    		BUSINESS PHONE:		484-875-3192

    	MAIL ADDRESS:
    		STREET 1:		101 LINDENWOOD DRIVE, SUITE 225
    		CITY:			MALVERN
    		STATE:			PA
    		ZIP:			19355

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	QR Pharma, Inc.
    		DATE OF NAME CHANGE:	20091202
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>ARS
    <SEQUENCE>1
    <FILENAME>tm254297d2_ars.pdf
    <DESCRIPTION>ARS
    <TEXT>
    Document 1 - file: tm254297d2_ars.pdf

    </DOCUMENT>
    </SEC-DOCUMENT>