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Stock-Based Compensation (Tables) | 9 Months Ended
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Sep. 30, 2025
Stock-Based Compensation |
Schedule of stock-based compensation expense | Stock-based compensation expense reflected in the statement of operations was as follows:
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Three Months Ended | ​ | Nine Months Ended
​ | ​ | September 30, | ​ | September 30,
​ |  | 2025 |  | 2024 | ​ | 2025 |  | 2024
General and administrative | ​ | $ | 232,852 | ​ | $ | 203,785 | ​ | $ | 770,185 | ​ | $ | 1,437,305
Research and development | ​ |  | 211,795 | ​ | ​ | 189,295 | ​ |  | 670,967 | ​ | ​ | 917,052
​ | ​ | $ | 444,647 | ​ | $ | 393,080 | ​ | $ | 1,441,152 | ​ | $ | 2,354,357
Schedule of stock option activity | The following table summarizes stock option activity:
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ |  | ​ |  | ​ | ​ |  | Weighted |  | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | Average | ​ | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | Remaining | ​ | Aggregate
​ | ​ | ​ | ​ | Weighted | ​ | Contractual | ​ | Intrinsic
​ | ​ | Number of | ​ | Average | ​ | Life | ​ | Value
​ | ​ | Options | ​ | Exercise Price | ​ | (Years) | ​ | (Thousands)
Options outstanding at December 31, 2024 |  | 2,336,020 | ​ | $ | 11.39 | ​ | 7.3 | ​ | $ 1,298
Options granted | ​ | 220,000 | ​ | $ | 2.09 | ​ | — | ​ | —
Options expired | ​ | (92,562) | ​ | $ | 10.12 | ​ | — | ​ | —
Options outstanding at September 30, 2025 |  | 2,463,458 | ​ | $ | 10.61 | ​ | 7.0 |  | $ 245
Options exercisable at September 30, 2025 | ​ | 1,994,267 | ​ | $ | 12.08 | ​ | 6.6 |  | $ 238

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