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Collaboration agreements - Contract Assets and Liabilities (Details) - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2022 | Sep. 30, 2021 | Sep. 30, 2022 | Sep. 30, 2021
GSK Agreement |  |  |  |
Contract liabilities |  |  |  |
Balance at Beginning of Period |  |  | $ 0 |
Additions |  |  | 100,000 |
Deductions |  |  | 655 |
Balance at End of Period | $ 99,345 |  | 99,345 |
Amounts included in the contract liability at the beginning of the period | 0 |  | 0 |
Performance obligations satisfied in previous periods | 0 |  | 0 |
Janssen Agreement |  |  |  |
Contract liabilities |  |  |  |
Balance at Beginning of Period |  |  | 0 |
Additions |  |  | 40,000 |
Deductions |  |  | 10,916 |
Balance at End of Period | 29,084 |  | 29,084 |
Amounts included in the contract liability at the beginning of the period | 4,908 |  | 0 |
Performance obligations satisfied in previous periods | 0 |  | 0 |
License and supply agreement Merck KGaA |  |  |  |
Contract liabilities |  |  |  |
Balance at Beginning of Period |  |  | 3,944 | $ 3,987
Additions |  |  | 0 | 0
Deductions |  |  | 32 | 32
Balance at End of Period | 3,912 | $ 3,955 | 3,912 | 3,955
Amounts included in the contract liability at the beginning of the period | 11 | 11 | 32 | 32
Performance obligations satisfied in previous periods | $ 0 | $ 0 | $ 0 | $ 0

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- Definition Amount of obligation to transfer good or service to customer for which consideration has been received or is receivable. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 45 -Paragraph 1 -URI https://asc.fasb.org/extlink&oid=126919976&loc=SL49130531-203044 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 50 -Paragraph 8 -Subparagraph (a) -URI https://asc.fasb.org/extlink&oid=126920106&loc=SL49130549-203045 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 45 -Paragraph 2 -URI https://asc.fasb.org/extlink&oid=126919976&loc=SL49130532-203044 + Details
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- Definition Amount of revenue recognized that was previously included in balance of obligation to transfer good or service to customer for which consideration from customer has been received or is due. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 50 -Paragraph 8 -Subparagraph (b) -URI https://asc.fasb.org/extlink&oid=126920106&loc=SL49130549-203045 + Details
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- Definition Amount of revenue recognized from performance obligation satisfied or partially satisfied in previous reporting periods. Includes, but is not limited to, change in transaction price. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 50 -Paragraph 12A -URI https://asc.fasb.org/extlink&oid=126920106&loc=SL108322424-203045 + Details
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