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Nature of business and basis of presentation (Details) - USD ($) $ in Thousands	3 Months Ended						9 Months Ended
	Sep. 30, 2022	Jun. 30, 2022	Mar. 31, 2022	Sep. 30, 2021	Jun. 30, 2021	Mar. 31, 2021	Sep. 30, 2022	Sep. 30, 2021	Dec. 31, 2021
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Net loss	$ (59,811)	$ (52,219)	$ (47,258)	$ (45,471)	$ (40,913)	$ (34,693)	$ (159,288)	$ (121,077)
Accumulated deficit	$ (609,767)						$ (609,767)		$ (450,479)

X

- Definition

The portion of profit or loss for the period, net of income taxes, which is attributable to the parent.

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