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Stock-based compensation - Restricted Stock Units (Details) - Restricted stock units - shares
9 Months Ended
Sep. 30, 2022
Dec. 31, 2021
Stock options    
Awards outstanding (in shares) 1,870,682 817,609
Granted (in shares) 1,379,849  
Vested (in shares) (190,841)  
Share-based compensation arrangement by share-based payment award, equity instruments other than options, forfeited in period (135,935)