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Stock-based compensation - Stock Based Compensation Expense by Award Type (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Stock options        
Stock-based compensation expense included in total operating expenses $ 5,375 $ 4,928 $ 16,208 $ 13,549
Stock options        
Stock options        
Stock-based compensation expense included in total operating expenses 3,901 3,986 11,952 10,617
Restricted stock units        
Stock options        
Stock-based compensation expense included in total operating expenses 1,365 881 3,832 2,636
Employee stock purchase plan        
Stock options        
Stock-based compensation expense included in total operating expenses $ 109 $ 61 $ 424 $ 296