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Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2024
Sep. 30, 2023
Sep. 30, 2024
Sep. 30, 2023
Income Statement [Abstract]        
Collaboration revenue $ 12,598 $ 7,698 $ 24,136 $ 26,154
Operating expenses:        
Research and development 14,803 30,531 50,734 126,774
General and administrative 9,864 12,894 31,927 49,409
Restructuring expenses 0 8,214 0 8,214
Total operating expenses 24,667 51,639 82,661 184,397
Other income (expense):        
Interest income 1,972 3,302 6,839 9,142
Interest expense (986) (1,017) (2,971) (3,025)
Total other income, net 986 2,285 3,868 6,117
Loss before income taxes (11,083) (41,656) (54,657) (152,126)
Income tax expense (418) 0 (418) 0
Net loss (11,501) (41,656) (55,075) (152,126)
Unrealized gain on marketable securities, net of tax 96 50 14 153
Comprehensive loss (11,405) (41,606) (55,061) (151,973)
Net loss attributable to common stockholders — basic (11,501) (41,656) (55,075) (152,126)
Net loss attributable to common stockholders — diluted $ (11,501) $ (41,656) $ (55,075) $ (152,126)
Net loss per share attributable to common stockholders — basic (in dollars per share) $ (0.09) $ (0.35) $ (0.45) $ (1.33)
Net loss per share attributable to common stockholders — diluted (in dollars per share) $ (0.09) $ (0.35) $ (0.45) $ (1.33)
Weighted-average number of shares of common stock used in net loss per share attributable to common stockholders — basic (in shares) 122,721,918 120,521,985 122,197,585 114,595,910
Weighted-average number of shares of common stock used in net loss per share attributable to common stockholders — diluted (in shares) 122,721,918 120,521,985 122,197,585 114,595,910