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Stock-based compensation - Schedule of Stock-Based Compensation Expense as Reflected in the Company's Condensed Consolidated Statements of Operations and Comprehensive Loss (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2024
Sep. 30, 2023
Sep. 30, 2024
Sep. 30, 2023
Stock options        
Share-based compensation expense $ 4,027 $ 4,001 $ 13,112 $ 17,051
Research and development        
Stock options        
Share-based compensation expense 2,305 2,153 7,195 8,881
General and administrative        
Stock options        
Share-based compensation expense $ 1,722 $ 1,848 $ 5,917 $ 8,170