<DOCUMENT>
<TYPE>EX-32.1
<SEQUENCE>4
<FILENAME>yrend_ex321ceo.txt
<DESCRIPTION>SECTION 906 CEO CERTIFICATION
<TEXT>
EXHIBIT 32.1
------------

                              UNITED-GUARDIAN, INC.
                    CERTIFICATION OF CHIEF EXECUTIVE OFFICER
                       PURSUANT TO 18 U.S.C. SECTION 1350,
                    AS ADOPTED PURSUANT TO SECTION 906 OF THE
                           SARBANES-OXLEY ACT OF 2002



     I, Kenneth H. Globus,  President of United-Guardian,  Inc., hereby certify,
pursuant to 18 U.S.C.  Section 1350,  as adopted  pursuant to Section 906 of the
Sarbanes-Oxley Act of 2002, that the Annual Report of  United-Guardian,  Inc. on
Form 10-KSB for the fiscal year ended  December 31, 2006 fully complies with the
requirements  of Section 13(a) or 15(d) of the Securities  Exchange Act of 1934,
and that  information  contained  in this Form  10-KSB  fairly  presents  in all
material  respects  the  financial   condition  and  results  of  operations  of
United-Guardian, Inc.


Date:  March 27, 2007                    By: /s/ Kenneth H. Globus
                                             ---------------------
                                             Kenneth H. Globus







</TEXT>
</DOCUMENT>
