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INTANGIBLE ASSETS (Details) - USD ($)
3 Months Ended 12 Months Ended
Mar. 31, 2023
Dec. 31, 2022
INTANGIBLE ASSETS    
Net Book Value $ 960,726  
License rights from related parties    
INTANGIBLE ASSETS    
Gross Carrying Amount 136,665,000 $ 136,665,000
Accumulated Amortization (135,976,594) (135,280,942)
Net Book Value $ 688,406 $ 1,384,058
License rights from related parties | Minimum    
INTANGIBLE ASSETS    
Weighted Average Useful Life 3 years 3 years
License rights from related parties | Maximum    
INTANGIBLE ASSETS    
Weighted Average Useful Life   5 years
License rights    
INTANGIBLE ASSETS    
Gross Carrying Amount $ 3,000,000 $ 3,000,000
Accumulated Amortization $ (3,000,000) $ (3,000,000)
Weighted Average Useful Life 5 years 5 years
Software    
INTANGIBLE ASSETS    
Gross Carrying Amount $ 51,784 $ 51,784
Accumulated Amortization $ (51,784) $ (51,784)
Weighted Average Useful Life 3 years 3 years
Trademark    
INTANGIBLE ASSETS    
Gross Carrying Amount $ 10,745 $ 10,745
Accumulated Amortization (9,311) (9,110)
Net Book Value $ 1,434 $ 1,635
Weighted Average Useful Life 12 years 12 years
In-progress patent    
INTANGIBLE ASSETS    
Gross Carrying Amount $ 270,886 $ 270,886
Net Book Value 270,886 270,886
Other    
INTANGIBLE ASSETS    
Gross Carrying Amount 333,415 333,415
Accumulated Amortization (61,095) (60,894)
Net Book Value $ 272,320 $ 272,521