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Loss per share - Antidilutive securities (Details) - shares
3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Share options        
Antidilutive securities        
Potentially dilutive equity instruments excluded from the diluted loss per share (in shares) 2,791,651 75,087,783 88,869,497 69,136,398