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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2019 | Mar. 31, 2018
Cash flows from operating activities |  |
Net loss | $ (27,412) | $ (21,078)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation | 1,828 | 1,740
Amortization | 167 | 143
Share-based compensation expense | 3,479 | 4,672
Realized loss on available-for-sale debt securities | 0 | 1,163
Unrealized foreign exchange gains | (5,095) | (7,862)
Other | (39) | 124
Changes in operating assets and liabilities: |  |
Increase in receivables and other operating assets | (6,659) | (10,179)
Increase in non-current operating assets | (19) | (123)
Decrease in payables and deferred revenue | (2,453) | (15,879)
Net cash used in operating activities | (36,203) | (47,279)
Cash flows from investing activities |  |
Acquisition of property, plant and equipment | (904) | (1,904)
Acquisition of intangibles | (205) | (10)
Maturity or redemption of marketable securities | 22,669 | 28,043
Investment in marketable securities | (3,904) | (12,490)
Net cash provided by investing activities | 17,656 | 13,639
Cash flows from financing activities |  |
Proceeds from exercise of stock options | 36 | 1,534
Net cash provided by financing activities | 36 | 1,534
Effect of currency exchange rate changes on cash, cash equivalents and restricted cash | 425 | 1,545
Net decrease in cash and cash equivalents | (18,086) | (30,561)
Cash, cash equivalents and restricted cash at start of period | 72,476 | 88,296
Cash, cash equivalents and restricted cash at end of period | $ 54,390 | $ 57,735

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