UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) $ in Thousands	3 Months Ended
Mar. 31, 2019	Mar. 31, 2018
UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
Revenue	$ 0	$ 8,196
Operating expenses
Research and development	(22,019)	(25,732)
General and administrative	(11,773)	(11,204)
Total operating expenses	(33,792)	(36,936)
Operating loss	(33,792)	(28,740)
Interest income	952	659
Other income, net	5,430	7,130
Loss before income taxes	(27,410)	(20,951)
Income taxes	(2)	(127)
Net loss attributable to ordinary shareholders	$ (27,412)	$ (21,078)
Net loss per ordinary share - Basic and diluted
Basic and diluted (in dollars per share)	$ (0.04)	$ (0.04)
Weighted average shares outstanding:
Basic and diluted (in shares)	627,945,243	562,381,995

Total costs of sales and operating expenses for the period.

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