<SEC-DOCUMENT>0001209191-21-026862.txt : 20210415
<SEC-HEADER>0001209191-21-026862.hdr.sgml : 20210415
<ACCEPTANCE-DATETIME>20210415181636
ACCESSION NUMBER:		0001209191-21-026862
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20210413
FILED AS OF DATE:		20210415
DATE AS OF CHANGE:		20210415

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			MAKOWER JOSHUA
		CENTRAL INDEX KEY:			0001235952

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-40315
		FILM NUMBER:		21829623

	MAIL ADDRESS:	
		STREET 1:		1212 TERRA BELLA AVENUE
		CITY:			MOUNTAIN VIEW
		STATE:			CA
		ZIP:			94043

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			SANDELL SCOTT D
		CENTRAL INDEX KEY:			0001237289

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-40315
		FILM NUMBER:		21829622

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			BASKETT FOREST
		CENTRAL INDEX KEY:			0001277631

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-40315
		FILM NUMBER:		21829626

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Sonsini Peter W.
		CENTRAL INDEX KEY:			0001559807

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-40315
		FILM NUMBER:		21829621

	MAIL ADDRESS:	
		STREET 1:		2855 SAND HILL ROAD
		CITY:			MENLO PARK
		STATE:			CA
		ZIP:			94025

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			NEA 15 GP, LLC
		CENTRAL INDEX KEY:			0001640033
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-40315
		FILM NUMBER:		21829627

	BUSINESS ADDRESS:	
		STREET 1:		1954 GREENSPRING DRIVE
		STREET 2:		SUITE 600
		CITY:			TIMONIUM
		STATE:			MD
		ZIP:			21093
		BUSINESS PHONE:		410-842-4000

	MAIL ADDRESS:	
		STREET 1:		1954 GREENSPRING DRIVE
		STREET 2:		SUITE 600
		CITY:			TIMONIUM
		STATE:			MD
		ZIP:			21093

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			New Enterprise Associates 15, L.P.
		CENTRAL INDEX KEY:			0001629794
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-40315
		FILM NUMBER:		21829629

	BUSINESS ADDRESS:	
		STREET 1:		1954 GREENSPRING DRIVE, SUITE 600
		CITY:			TIMONIUM
		STATE:			MD
		ZIP:			21093
		BUSINESS PHONE:		410-842-4000

	MAIL ADDRESS:	
		STREET 1:		1954 GREENSPRING DRIVE, SUITE 600
		CITY:			TIMONIUM
		STATE:			MD
		ZIP:			21093

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Makhzoumi Mohamad
		CENTRAL INDEX KEY:			0001630226

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-40315
		FILM NUMBER:		21829624

	MAIL ADDRESS:	
		STREET 1:		2855 SAND HILL ROAD
		CITY:			MENLO PARK
		STATE:			CA
		ZIP:			94025

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Florence Anthony A. Jr.
		CENTRAL INDEX KEY:			0001559827

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-40315
		FILM NUMBER:		21829625

	MAIL ADDRESS:	
		STREET 1:		5425 WISCONSIN AVENUE, SUITE 800
		CITY:			CHEVY CHASE
		STATE:			MD
		ZIP:			20815

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			NEA Partners 15, L.P.
		CENTRAL INDEX KEY:			0001640031
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-40315
		FILM NUMBER:		21829628

	BUSINESS ADDRESS:	
		STREET 1:		1954 GREENSPRING DRIVE
		STREET 2:		SUITE 600
		CITY:			TIMONIUM
		STATE:			MD
		ZIP:			21093
		BUSINESS PHONE:		410-842-4000

	MAIL ADDRESS:	
		STREET 1:		1954 GREENSPRING DRIVE
		STREET 2:		SUITE 600
		CITY:			TIMONIUM
		STATE:			MD
		ZIP:			21093

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Reneo Pharmaceuticals, Inc.
		CENTRAL INDEX KEY:			0001637715
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				472309515
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		P.O. BOX 675614
		CITY:			RANCHO SANTA FE
		STATE:			CA
		ZIP:			92067
		BUSINESS PHONE:		619-733-3852

	MAIL ADDRESS:	
		STREET 1:		P.O. BOX 675614
		CITY:			RANCHO SANTA FE
		STATE:			CA
		ZIP:			92067
</SEC-HEADER>
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            <rptOwnerStreet2></rptOwnerStreet2>
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            <rptOwnerState>MD</rptOwnerState>
            <rptOwnerZipCode>20815</rptOwnerZipCode>
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    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001630226</rptOwnerCik>
            <rptOwnerName>Makhzoumi Mohamad</rptOwnerName>
        </reportingOwnerId>
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            <rptOwnerStreet1>2855 SAND HILL ROAD</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>MENLO PARK</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>94025</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
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    <reportingOwner>
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            <rptOwnerCik>0001235952</rptOwnerCik>
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            <rptOwnerState>MD</rptOwnerState>
            <rptOwnerZipCode>21093</rptOwnerZipCode>
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    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001559807</rptOwnerCik>
            <rptOwnerName>Sonsini Peter W.</rptOwnerName>
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        <reportingOwnerAddress>
            <rptOwnerStreet1>2855 SAND HILL ROAD</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
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    <nonDerivativeTable>
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                <value>Common Stock</value>
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            <transactionDate>
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            <deemedExecutionDate></deemedExecutionDate>
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                <value></value>
            </transactionTimeliness>
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                    <value>2128956</value>
                </transactionShares>
                <transactionPricePerShare>
                    <footnoteId id="F1"/>
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            <transactionDate>
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            <deemedExecutionDate></deemedExecutionDate>
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            <transactionTimeliness>
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            <transactionAmounts>
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        </nonDerivativeTransaction>
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            <transactionDate>
                <value>2021-04-13</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
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                <transactionFormType>4</transactionFormType>
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                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F3"/>
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                <value></value>
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                    <value>666666</value>
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                    <value>15.00</value>
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                    <value>4785494</value>
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                    <value>D</value>
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    <derivativeTable>
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            <securityTitle>
                <value>Series A Preferred Stock</value>
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                <footnoteId id="F1"/>
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            <transactionDate>
                <value>2021-04-13</value>
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                <transactionCode>C</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
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                <value></value>
            </transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>9526652</value>
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                <transactionPricePerShare>
                    <value>0.00</value>
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                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
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            <exerciseDate>
                <footnoteId id="F1"/>
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            <expirationDate>
                <footnoteId id="F1"/>
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            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
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                <underlyingSecurityShares>
                    <value>2128956</value>
                </underlyingSecurityShares>
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                    <value>D</value>
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                <footnoteId id="F1"/>
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                <value>2021-04-13</value>
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                <transactionFormType>4</transactionFormType>
                <transactionCode>C</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
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            <transactionTimeliness>
                <value></value>
            </transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>8904280</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0.00</value>
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                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
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            <exerciseDate>
                <footnoteId id="F1"/>
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                <footnoteId id="F1"/>
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                <underlyingSecurityTitle>
                    <value>Common Stock</value>
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                    <value>1989872</value>
                </underlyingSecurityShares>
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                    <value>0</value>
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    <footnotes>
        <footnote id="F1">All outstanding shares of Preferred Stock automatically converted into shares of Common Stock immediately prior to the closing of the Issuer's initial public offering, for no additional consideration at a rate of 1 share of Common Stock for each 4.4748 shares of Preferred Stock. The Preferred Stock had no expiration date.</footnote>
        <footnote id="F2">The shares are directly held by New Enterprise Associates 15, L.P. (&quot;NEA 15&quot;), and indirectly held by NEA Partners 15, L.P. (&quot;NEA Partners 15&quot;), the sole general partner of NEA 15, NEA 15 GP, LLC (&quot;NEA 15 GP&quot;), the sole general partner of NEA Partners 15, and the individual managers of NEA 15 GP (NEA Partners 15, NEA 15 GP and the individual managers of NEA 15 GP, together, the &quot;Indirect Reporting Persons&quot;). The individual managers of NEA 15 GP are Forest Baskett, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, Scott D. Sandell and Peter W. Sonsini. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the NEA 15 shares in which the Indirect Reporting Persons have no pecuniary interest.</footnote>
        <footnote id="F3">The shares were purchased in the Issuer's initial public offering.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Sasha Keough, attorney-in-fact</signatureName>
        <signatureDate>2021-04-15</signatureDate>
    </ownerSignature>
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