<SEC-DOCUMENT>0000950170-25-036341-index.html : 20250310
<SEC-HEADER>0000950170-25-036341.hdr.sgml : 20250310
<ACCEPTANCE-DATETIME>20250310162520
ACCESSION NUMBER:		0000950170-25-036341
CONFORMED SUBMISSION TYPE:	424B3
PUBLIC DOCUMENT COUNT:		9
FILED AS OF DATE:		20250310
DATE AS OF CHANGE:		20250310

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			OnKure Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001637715
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				472309515
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		424B3
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-282792
		FILM NUMBER:		25724071

	BUSINESS ADDRESS:	
		STREET 1:		6707 WINCHESTER CIRCLE, SUITE 400
		CITY:			BOULDER
		STATE:			CO
		ZIP:			80301
		BUSINESS PHONE:		(720) 307-2892

	MAIL ADDRESS:	
		STREET 1:		6707 WINCHESTER CIRCLE, SUITE 400
		CITY:			BOULDER
		STATE:			CO
		ZIP:			80301

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Reneo Pharmaceuticals, Inc.
		DATE OF NAME CHANGE:	20150325
</SEC-HEADER>
<DOCUMENT>
<TYPE>424B3
<SEQUENCE>1
<FILENAME>424b3_okur_10-k_2024_202.htm
<DESCRIPTION>424B3
<TEXT>
Document 1 - file: 424b3_okur_10-k_2024_202.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>img206454441_0.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 2 - file: img206454441_0.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>img206454441_1.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 3 - file: img206454441_1.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>img206454441_2.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: img206454441_2.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>img206454441_3.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 5 - file: img206454441_3.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>img206454441_4.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 6 - file: img206454441_4.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>img206454441_5.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 7 - file: img206454441_5.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>8
<FILENAME>img206454441_6.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 8 - file: img206454441_6.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>9
<FILENAME>img206454441_7.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 9 - file: img206454441_7.jpg

</DOCUMENT>
</SEC-DOCUMENT>