<SEC-DOCUMENT>0000950170-25-078388-index.html : 20250528
<SEC-HEADER>0000950170-25-078388.hdr.sgml : 20250528
<ACCEPTANCE-DATETIME>20250528163519
ACCESSION NUMBER:		0000950170-25-078388
CONFORMED SUBMISSION TYPE:	424B3
PUBLIC DOCUMENT COUNT:		2
FILED AS OF DATE:		20250528
DATE AS OF CHANGE:		20250528

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			OnKure Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001637715
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				472309515
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		424B3
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-282792
		FILM NUMBER:		25995902

	BUSINESS ADDRESS:	
		STREET 1:		6707 WINCHESTER CIRCLE, SUITE 400
		CITY:			BOULDER
		STATE:			CO
		ZIP:			80301
		BUSINESS PHONE:		(720) 307-2892

	MAIL ADDRESS:	
		STREET 1:		6707 WINCHESTER CIRCLE, SUITE 400
		CITY:			BOULDER
		STATE:			CO
		ZIP:			80301

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Reneo Pharmaceuticals, Inc.
		DATE OF NAME CHANGE:	20150325
</SEC-HEADER>
<DOCUMENT>
<TYPE>424B3
<SEQUENCE>1
<FILENAME>424b3_okur_8k_20250528.htm
<DESCRIPTION>424B3
<TEXT>
Document 1 - file: 424b3_okur_8k_20250528.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>img23824010_0.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 2 - file: img23824010_0.jpg

</DOCUMENT>
</SEC-DOCUMENT>