<DOCUMENT>
<TYPE>EX-4.41
<SEQUENCE>19
<FILENAME>ex4-41.txt
<DESCRIPTION>AMENDMENT OF PURCHASE AGREEMENT DATED 8/25/2000
<TEXT>
                                                                    Exhibit 4.41

April 15, 2002

K. Tucker Anderson
61 Above All Road
Warren, CT 06754

Dear Mr. Andersen:

This letter serves as an agreement between Milestone Scientific and K. Tucker
Andersen whereby Mr. Andersen provides Milestone with a $200,000 line of credit
effective immediately, payable in cash through January 2, 2003. Interest will be
computed at 6% and the specifics of the warrant agreement attached to this loan
will be determined at a later date.

Sincerely,


Thomas M. Stuckey
VP and CFO

_________________________________
K. Tucker Andersen

</TEXT>
</DOCUMENT>
