<DOCUMENT>
<TYPE>EX-32.2
<SEQUENCE>7
<FILENAME>d63930_ex32-2.txt
<DESCRIPTION>CERTIFICATION PURSUANT
<TEXT>
                                  Exhibit 32.2
                            CERTIFICATION PURSUANT TO
                             18 U.S.C. SECTION 1350,
                             AS ADOPTED PURSUANT TO

SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

In connection with the Quarterly  Report of Milestone  Scientific,  Inc. on Form
10-QSB for the three months  ending March 31, 2005 as filed with the  Securities
and Exchange Commission on the date hereof (the "Report"),  I, Kevin T. Lusardi,
Chief Financial Officer of Milestone, certify pursuant to 18 U.S.C. ss. 1350, as
adopted  pursuant to ss. 906 of the  Sarbanes-Oxley  Act of 2002,  that: (1) The
Report fully  complies  with the  requirements  of section 13(a) or 15(d) of the
Securities Exchange Act of 1934; and (2) The information contained in the Report
fairly presents, in all material respects, the financial condition and result of
operations of Milestone.


                                    /s/ Kevin T. Lusardi
                                    --------------------------
                                    Kevin T. Lusardi
                                    Chief Financial Officer
                                    May 17, 2005


                                       24
</TEXT>
</DOCUMENT>
