-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 PbIPttOuMXSHEZYA5KIKkggY0YYUgsREnMKFqk554LSFVuD3c4cgZId8rAKM7l+d
 Ve1nW85IEvk0o2p4B+SGqg==

<SEC-DOCUMENT>0001143313-06-000357.txt : 20061016
<SEC-HEADER>0001143313-06-000357.hdr.sgml : 20061016
<ACCEPTANCE-DATETIME>20061016121417
ACCESSION NUMBER:		0001143313-06-000357
CONFORMED SUBMISSION TYPE:	25-NSE
PUBLIC DOCUMENT COUNT:		2
FILED AS OF DATE:		20061016
DATE AS OF CHANGE:		20061016
EFFECTIVENESS DATE:		20061016

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MILESTONE SCIENTIFIC INC/NJ
		CENTRAL INDEX KEY:			0000855683
		STANDARD INDUSTRIAL CLASSIFICATION:	ORTHOPEDIC, PROSTHETIC & SURGICAL APPLIANCES & SUPPLIES [3842]
		IRS NUMBER:				133545623
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		25-NSE
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-14053
		FILM NUMBER:		061145580

	BUSINESS ADDRESS:	
		STREET 1:		220 S ORANGE AVE
		STREET 2:		LIVINGSTON CORPORATE PARK
		CITY:			LIVINGSTON
		STATE:			NJ
		ZIP:			07039
		BUSINESS PHONE:		2013793171

	MAIL ADDRESS:	
		STREET 1:		44 KEAN ROAD
		STREET 2:		220 SOUTH ORANGE AVE
		CITY:			LIVINGSTON
		STATE:			NJ
		ZIP:			07039

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	U S OPPORTUNITY SEARCH INC
		DATE OF NAME CHANGE:	19920703

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			AMERICAN STOCK EXCHANGE LLC
		CENTRAL INDEX KEY:			0001143313
		IRS NUMBER:				522127241

	FILING VALUES:
		FORM TYPE:		25-NSE

	BUSINESS ADDRESS:	
		STREET 1:		86 TRINITY PLACE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10006
		BUSINESS PHONE:		212-306-1000

	MAIL ADDRESS:	
		STREET 1:		86 TRINITY PLACE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10006
</SEC-HEADER>
<DOCUMENT>
<TYPE>25-NSE
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<notificationOfRemoval>

    <schemaVersion>X0203</schemaVersion>

    <exchange>
        <cik>0001143313</cik>
        <entityName>AMERICAN STOCK EXCHANGE LLC</entityName>
    </exchange>

    <issuer>
        <cik>0000855683</cik>
        <entityName>MILESTONE SCIENTIFIC INC/NJ</entityName>
        <fileNumber>001-14053</fileNumber>
        <address>
            <street1>220 South Orange Avenue</street1>
            <street2>Livingston Corporate Park</street2>
            <city>Livingston</city>
            <stateOrCountryCode>NJ</stateOrCountryCode>
            <stateOrCountry>NEW JERSEY</stateOrCountry>
            <zipCode>07039</zipCode>
        </address>
        <telephoneNumber>2013793171</telephoneNumber>
    </issuer>

    <descriptionClassSecurity>Common Stock, $0.001 Par Value &amp; Redeemable Common Stock Purchase Warrants</descriptionClassSecurity>

    <ruleProvision>17 CFR 240.12d2-2(b)</ruleProvision>

    <signatureData>
        <signatureName>Dennis J. Meekins</signatureName>
        <signatureTitle>Vice President - Listing Qualifications</signatureTitle>
        <signatureDate>2006-10-16</signatureDate>
    </signatureData>
</notificationOfRemoval>
</XML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.25
<SEQUENCE>2
<FILENAME>mss08282006lostappeal.htm
<TEXT>
<!doctype html public "-//IETF//DTD HTML//EN">
<HTML>
<HEAD>
<TITLE>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;BEFORE THE</TITLE>
<META NAME="author" CONTENT="EMPLOYEE">
<META NAME="date" CONTENT="08/28/2006">
</HEAD>
<BODY style="line-height:12pt; font-family:Times New Roman; font-size:10pt; color:#000000">
<DIV style="width:450pt"><P style="line-height:13pt; margin:0pt; padding-right:-13.5pt; font-size:11pt" align=center><U>AMERICAN STOCK EXCHANGE LLC</U></P>
<P style="margin:0pt" align=center><BR></P>
<P style="line-height:13pt; margin:0pt; padding-right:-13.5pt; font-size:11pt" align=center>DETERMINATION AND NOTIFICATION OF REMOVAL FROM LISTING</P>
<P style="line-height:13pt; margin:0pt; padding-right:-13.5pt; font-size:11pt" align=center>AND/OR REGISTRATION UNDER SECTION 12(b) OF THE</P>
<P style="line-height:13pt; margin:0pt; padding-right:-13.5pt; font-size:11pt" align=center>SECURITIES EXCHANGE ACT OF 1934</P>
<P style="line-height:13pt; margin:0pt; padding-right:-13.5pt; font-size:11pt" align=center>Attachment to Form 25</P>
<P style="margin:0pt" align=center><BR></P>
<P style="line-height:13pt; margin:0pt; padding-right:-13.5pt; font-size:11pt" align=center>October 16, 2006</P>
<P style="margin:0pt"><BR></P>
<P style="line-height:13pt; margin:0pt; text-indent:36pt; font-size:11pt" align=justify>The American Stock Exchange LLC (the &#147;Exchange&#148; or &#147;Amex&#148;), pursuant to Section 12(d) of the Securities Exchange Act of 1934 and Rule 12d2-2(b) promulgated thereunder by the Securities and Exchange Commission (the &#147;Commission&#148;), has determined to strike from listing and registration on the Exchange, the following:</P>
<P style="margin:0pt"><BR></P>
<P style="line-height:13pt; margin:0pt; font-size:11pt" align=center><B>&nbsp;&nbsp;MILESTONE SCIENTIFIC, INC. </B></P>
<P style="line-height:13pt; margin:0pt; font-size:11pt" align=center><U>Common Stock, $0.001 Par Value</U></P>
<P style="line-height:13pt; margin-top:4.6pt; margin-bottom:4.6pt; font-size:11pt" align=center><U>Redeemable Common Stock Purchase Warrants</U></P>
<P style="line-height:13pt; margin:0pt; font-size:11pt" align=center><U>Commission File Number &#150; 001-14053</U></P>
<P style="margin:0pt"><BR></P>
<P style="line-height:13pt; margin-top:0pt; margin-bottom:-13pt; font-size:11pt" align=justify>1.</P>
<P style="line-height:13pt; margin:0pt; text-indent:36pt; font-size:11pt" align=justify>The standards of the Exchange provide, among other things, that consideration may be given to the removal of a security when: <FONT FACE="CG Times">(i) the financial condition and/or operating results of the issuer appear to be unsatisfactory; or (ii) any other event shall occur or any condition shall exist which makes further dealings on the Exchange unwarranted.</FONT> </P>
<P style="margin:0pt" align=justify><BR></P>
<P style="line-height:13pt; margin:0pt; text-indent:36pt; font-family:CG Times; font-size:11pt" align=justify><FONT FACE="CG Times">In applying these standards, the Exchange gives consideration to delisting the securities of a company that is not in compliance with Section 1003(a)(iii) of the Amex Company Guide (the &#147;Company Guide&#148;) which requires a company to maintain at least $6 million in shareholders&#146; equity if the company has reported losses from continuing operations and/or net losses in its five most recent fiscal years; and</FONT></P>
<P style="margin:0pt" align=justify><BR></P>
<P style="line-height:13pt; margin-top:0pt; margin-bottom:-13pt; font-size:11pt" align=justify><FONT FACE="Times New Roman">2.</FONT></P>
<P style="line-height:13pt; margin:0pt; text-indent:36pt; font-size:11pt" align=justify>The Common Stock of Milestone Scientific, Inc. (the &#147;Company&#148;) does not qualify for continued listing for the following reasons:</P>
<P style="margin:0pt" align=justify><BR></P>
<P style="line-height:13pt; margin-top:0pt; margin-bottom:-13pt; padding-left:72pt; text-indent:-36pt; font-size:11pt" align=justify>(a)</P>
<P style="line-height:13pt; margin:0pt; padding-left:72pt; font-size:11pt" align=justify>The Company has incurred net losses as follows:</P>
<P style="margin:0pt"><BR></P>
<P style="line-height:13pt; margin-top:0pt; margin-bottom:-13pt; text-indent:72pt; font-size:11pt"><U>Fiscal years ended</U></P>
<P style="line-height:13pt; margin-top:0pt; margin-bottom:-13pt; text-indent:162pt; font-size:11pt"><U>&nbsp;December 31,</U></P>
<P style="line-height:13pt; margin:0pt; text-indent:313.25pt; font-size:11pt"><U>Net (Loss)</U></P>
<P style="line-height:13pt; margin-top:0pt; margin-bottom:-13pt; text-indent:135pt; font-size:11pt">2005</P>
<P style="line-height:13pt; margin:0pt; text-indent:303.2pt; font-size:11pt">($2,754,000)</P>
<P style="line-height:13pt; margin-top:0pt; margin-bottom:-13pt; text-indent:135pt; font-size:11pt">2004</P>
<P style="line-height:13pt; margin:0pt; text-indent:303.2pt; font-size:11pt">($2,997,000)</P>
<P style="line-height:13pt; margin-top:0pt; margin-bottom:-13pt; text-indent:135pt; font-size:11pt">2003</P>
<P style="line-height:13pt; margin:0pt; text-indent:303.2pt; font-size:11pt">($2,413,000)</P>
<P style="line-height:13pt; margin-top:0pt; margin-bottom:-13pt; text-indent:135pt; font-size:11pt">2002</P>
<P style="line-height:13pt; margin:0pt; text-indent:303.2pt; font-size:11pt">($2,440,000)</P>
<P style="line-height:13pt; margin-top:0pt; margin-bottom:-13pt; text-indent:135pt; font-size:11pt">2001</P>
<P style="line-height:13pt; margin:0pt; text-indent:303.2pt; font-size:11pt">($3,992,000)</P>
<P style="margin:0pt"><BR></P>
<P style="line-height:13pt; margin:0pt; text-indent:108pt; font-size:11pt"><U>Six months ended </U></P>
<P style="line-height:13pt; margin-top:0pt; margin-bottom:-13pt; text-indent:121.5pt; font-size:11pt">June 30, 2006</P>
<P style="line-height:13pt; margin:0pt; text-indent:303.2pt; font-size:11pt">($1,640,000)</P>
<P style="margin:0pt"><BR></P>
<P style="line-height:13pt; margin-top:0pt; margin-bottom:-13pt; padding-left:72pt; text-indent:-36pt; font-size:11pt" align=justify>(b)</P>
<P style="line-height:13pt; margin:0pt; padding-left:72pt; font-size:11pt" align=justify>At June 30, 2006, the Company reported shareholders&#146; equity of $4,812,000. &nbsp;</P>
<P style="margin:0pt" align=justify><BR></P>
<P style="line-height:13pt; margin-top:0pt; margin-bottom:-13pt; font-size:11pt" align=justify>3.</P>
<P style="line-height:13pt; margin:0pt; text-indent:36pt; font-size:11pt" align=justify>In reviewing the eligibility of the Company&#146;s Common Stock for continued listing, the Exchange has complied with its standards and procedures as follows: </P>
<P style="margin:0pt" align=justify><BR></P>
<P style="line-height:13pt; margin-top:0pt; margin-bottom:-13pt; padding-left:72pt; text-indent:-18pt; font-family:CG Times; font-size:11pt" align=justify><FONT FACE="CG Times">(a)</FONT></P>
<P style="line-height:13pt; margin:0pt; padding-left:72pt; font-family:CG Times; font-size:11pt" align=justify>By letter dated June 15, 2006, the Company was advised <FONT FACE="Times New Roman">of its status in relation to the standards of the Exchange. &nbsp;</FONT>Specifically, the Company was not in compliance with Section with Section 1003(a)(iii) of the Company Guide. &nbsp;Pursuant to Section 1009(h) of the Company Guide, Staff determined that this instance on noncompliance was related to a prior instance of noncompliance in that both were related to the Company&#146;s operating results. &nbsp;Therefore, the Company was further advised of the Exchange Staff&#146;s (the &#147;Staff&#148;) determination to not offer the Company an opportunity to <FONT FACE="Times New Roman">present a plan in support of continued listing </FONT>and instead to proceed with immediate delisting procedures. &nbsp;The Company was also notified that, in accordance with Sections 1203 and 1009(d) of the Company Guide, it could a
ppeal Staff&#146;s determination no later than June 22, 2006 by requesting an oral or written hearing before a Listing Qualifications Panel of the Amex Committee on Securities (the &#147;Panel&#148;). </P>
<P style="margin:0pt" align=justify><BR></P>
<P style="line-height:13pt; margin-top:0pt; margin-bottom:-13pt; padding-left:72pt; text-indent:-18pt; font-family:CG Times; font-size:11pt" align=justify>(b)</P>
<P style="line-height:13pt; margin:0pt; padding-left:72pt; font-family:CG Times; font-size:11pt" align=justify>By correspondence dated June 19, 2006, the Company appealed the determination and requested an oral hearing to review the Staff&#146;s determination. </P>
<P style="margin:0pt" align=justify><BR></P>
<P style="line-height:13pt; margin-top:0pt; margin-bottom:-13pt; padding-left:72pt; text-indent:-18pt; font-size:11pt" align=justify><FONT FACE="Times New Roman">(c)</FONT></P>
<P style="line-height:13pt; margin:0pt; padding-left:72pt; font-size:11pt" align=justify>On August 16, 2006, a hearing at which the Company was present was conducted before the Panel. &nbsp;By letter dated August 17, 2006, the Exchange notified the Company of the Panel&#146;s decision to deny the Company&#146;s appeal for continued listing of its common stock on the Amex and to authorize delisting proceedings. &nbsp;The letter also informed the Company of its right, in accordance with Section 1205 of the Company Guide, to request that the Exchange&#146;s Committee on Securities review the Panel&#146;s decision within fifteen calendar days.</P>
<P style="margin:0pt" align=justify><BR></P>
<P style="line-height:13pt; margin-top:0pt; margin-bottom:-13pt; padding-left:72pt; text-indent:-18pt; font-size:11pt" align=justify>(d)</P>
<P style="line-height:13pt; margin:0pt; padding-left:72pt; font-size:11pt" align=justify>The Company did not appeal the Panel&#146;s decision to the Committee on Securities.</P>
<P style="margin:0pt" align=justify><BR></P>
<P style="line-height:13pt; margin:0pt; font-size:11pt" align=justify>Accordingly, the Exchange, having complied with all of its procedures, is authorized to file this application in accordance with Section 12 of the Securities Exchange Act of 1934 and the rules promulgated thereunder. </P>
<P style="margin:0pt" align=justify><BR></P>
<P style="line-height:13pt; margin-top:0pt; margin-bottom:-13pt; font-size:11pt" align=justify>4.</P>
<P style="line-height:13pt; margin:0pt; text-indent:36pt; font-size:11pt" align=justify>In the opinion of the Exchange, all of the material facts relating to the reasons for this application are contained herein.</P>
<P style="margin:0pt" align=justify><BR></P>
<P style="line-height:13pt; margin-top:0pt; margin-bottom:-13pt; font-family:CG Times; font-size:11pt" align=justify><FONT FACE="CG Times">5.</FONT></P>
<P style="line-height:13pt; margin:0pt; text-indent:36pt; font-family:CG Times; font-size:11pt" align=justify>The Exchange official whose signature is set forth below is duly authorized to file this application.</P>
<P style="margin:0pt" align=justify><BR></P>
<P style="line-height:13pt; margin-top:0pt; margin-bottom:-13pt; font-size:11pt" align=justify><FONT FACE="Times New Roman">6.</FONT></P>
<P style="line-height:13pt; margin:0pt; text-indent:36pt; font-size:11pt" align=justify>In accordance with the provisions of Rule 12d2-2, the Exchange has issued public notice of its final determination to remove the Company&#146;s securities from listing and/or registration by issuing a press release and posting notice on www.amex.com. &nbsp;Further, a copy of this application has been forwarded to Mr. Leonard Osser, Chief Executive Officer of Milestone Scientific, Inc.</P>
<P style="margin:0pt" align=justify><BR></P>
<P style="margin:0pt"><BR></P>
<P style="margin:0pt"><BR></P>
<P style="margin:0pt"><BR></P>
<P style="margin:0pt"><BR></P>
<P style="line-height:13pt; margin:0pt; font-family:CG Times; font-size:11pt"><FONT FACE="CG Times">/s/</FONT></P>
<P style="line-height:13pt; margin:0pt; font-family:CG Times; font-size:11pt">Dennis J. Meekins</P>
<P style="line-height:13pt; margin:0pt; font-family:CG Times; font-size:11pt">Vice President, Listing Qualifications </P>
<P style="line-height:13pt; margin:0pt; font-family:CG Times; font-size:11pt">American Stock Exchange LLC</P>
<P style="margin:0pt"><BR></P>
<P style="margin:0pt"><BR></P>
<P style="margin:0pt"><BR>
<BR></P>
</DIV></BODY>
</HTML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----
