-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 Q2d815fUtEg4yOmTU1fXMnl9CFvN23tjAnfySLBrhCmeQfV79iL/fanKHf1JpyA9
 sDvUBYszxfH3m0JApwgBHQ==

<SEC-DOCUMENT>0000950136-06-005119.txt : 20060620
<SEC-HEADER>0000950136-06-005119.hdr.sgml : 20060620
<ACCEPTANCE-DATETIME>20060620171234
ACCESSION NUMBER:		0000950136-06-005119
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20060615
ITEM INFORMATION:		Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing
ITEM INFORMATION:		Departure of Directors or Principal Officers; Election of Directors; Appointment of Principal Officers
ITEM INFORMATION:		Financial Statements and Exhibits
FILED AS OF DATE:		20060620
DATE AS OF CHANGE:		20060620

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MILESTONE SCIENTIFIC INC/NJ
		CENTRAL INDEX KEY:			0000855683
		STANDARD INDUSTRIAL CLASSIFICATION:	ORTHOPEDIC, PROSTHETIC & SURGICAL APPLIANCES & SUPPLIES [3842]
		IRS NUMBER:				133545623
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-14053
		FILM NUMBER:		06915784

	BUSINESS ADDRESS:	
		STREET 1:		220 S ORANGE AVE
		STREET 2:		LIVINGSTON CORPORATE PARK
		CITY:			LIVINGSTON
		STATE:			NJ
		ZIP:			07039
		BUSINESS PHONE:		2013793171

	MAIL ADDRESS:	
		STREET 1:		44 KEAN ROAD
		STREET 2:		220 SOUTH ORANGE AVE
		CITY:			LIVINGSTON
		STATE:			NJ
		ZIP:			07039

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	U S OPPORTUNITY SEARCH INC
		DATE OF NAME CHANGE:	19920703
</SEC-HEADER>
<DOCUMENT>
<TYPE>8-K
<SEQUENCE>1
<FILENAME>file1.htm
<TEXT>
<HTML>
<HEAD>
<TITLE>
</TITLE>
</HEAD>
<BODY>
<PRE><PAGE>

                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549
                         ------------------------------

                                    FORM 8-K

                                 CURRENT REPORT

                     PURSUANT TO SECTION 13 OR 15(d) OF THE
                         SECURITIES EXCHANGE ACT OF 1934



         DATE OF REPORT (DATE OF EARLIEST EVENT REPORTED) JUNE 15, 2006
                                                          -------------


                            MILESTONE SCIENTIFIC INC.
                            -------------------------
             (EXACT NAME OF REGISTRANT AS SPECIFIED IN ITS CHARTER)



              DELAWARE                   001-14053             13-3545623
  -------------------------------    ----------------      -------------------
  (STATE OR OTHER JURISDICTION OF    (COMMISSION FILE        (IRS EMPLOYER
           INCORPORATION)                 NUMBER)          IDENTIFICATION NO.)



220 SOUTH ORANGE AVENUE, LIVINGSTON CORPORATE PARK, LIVINGSTON, NEW JERSEY 07034
- --------------------------------------------------------------------------------
               (ADDRESS OF PRINCIPAL EXECUTIVE OFFICE) (ZIP CODE)


        REGISTRANT'S TELEPHONE NUMBER, INCLUDING AREA CODE (973) 535-2717
                                                           --------------


                                       N/A
          -------------------------------------------------------------
          (FORMER NAME OR FORMER ADDRESS, IF CHANGED SINCE LAST REPORT)

Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
following provisions:

[  ]  Written communications pursuant to Rule 425 under the Securities Act
      (17 CFR 230.425)

[  ]  Soliciting material pursuant to Rule 14a-12 under the Exchange Act
      (17 CFR 240.14a-12)

[  ]  Pre-commencement communications pursuant to Rule 14d-2(b) under the
      Exchange Act (17 CFR 240.14d-2(b))

[  ]  Pre-commencement communications pursuant to Rule 13e-4(c) under the
      Exchange Act (17 CFR 240.13e-4(c))

<PAGE>

ITEM 3.01: NOTICE OF DELISTING OR FAILURE TO SATISFY A CONTINUED LISTING RULE OR
           STANDARD; TRANSFER OF LISTING

         On June 16, 2006, Milestone Scientific Inc. ("Milestone") issued a
press release disclosing that on June 16, 2006 Milestone had received notice
from the American Stock Exchange ("AMEX") that it is not in compliance with
AMEX's continued listing standards related to shareholders' equity and losses as
specified in Section 1003(a)(iii) of the AMEX Company Guide, which requires
Milestone to have shareholder equity of $6,000,000. Milestone received a faxed
copy of the same notice on June 15, 2006. Milestone has appealed AMEX's
determination and requested a hearing before a Listing Qualification Panel. A
copy of the press release is attached as Exhibit 99.1.

ITEM 5.02: DEPARTURE OF DIRECTORS OR PRINCIPAL OFFICERS; ELECTION OF DIRECTORS;
           APPOINTMENT OF PRINCIPAL OFFICERS.

         On June 16, 2006, Milestone also announced that Stuart Wildhorn had
resigned his position as President of Milestone, effective June 30, 2006. On
June 20, 2006, Milestone's Board of Directors appointed Thomas Ronca as
President, effective June 30, 2006, in addition to his continuing duties as
Chief Operating Officer. Mr. Ronca's biographical details have been previously
reported in Milestone's annual report on Form 10-KSB filed with the Securities
and Exchange Commission on April 14, 2006.


ITEM 9.01: FINANCIAL STATEMENTS AND EXHIBITS
           ---------------------------------

           (c) Exhibits:

               99.1 Press Release dated June 16, 2006

                                   SIGNATURES

         Pursuant to the requirements of the Securities Exchange Act of 1934,
the Registrant has duly caused this Current Report on Form 8-K to be signed on
its behalf by the undersigned, hereunto duly authorized.


                                   MILESTONE SCIENTIFIC INC.

                                   By:  /s/ Leonard Osser
                                        ------------------------------------
                                        Leonard Osser
                                        Chairman and Chief Executive Officer

Dated:  June 20, 2006
</PRE>
</BODY>
</HTML>


</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>2
<FILENAME>file2.htm
<DESCRIPTION>PRESS RELEASE
<TEXT>
<HTML>
<HEAD>
<TITLE>
</TITLE>
</HEAD>
<BODY>
<PRE>
<PAGE>

FOR IMMEDIATE RELEASE

CONTACT
Leonard Osser, Chairman and CEO
MILESTONE SCIENTIFIC INC.
(973) 535-2717; (973) 535-2829 (Fax)
Web site: www.milesci.com

                            MILESTONE SCIENTIFIC INC.
                    RECEIVES NOTICE OF FAILURE TO COMPLY WITH
           CONTINUED LISTING STANDARDS OF THE AMERICAN STOCK EXCHANGE

                     STUART WILDHORN RESIGNS AS PRESIDENT OF
                            MILESTONE SCIENTIFIC INC.

LIVINGSTON, NEW JERSEY, JUNE 16, 2006 -- MILESTONE SCIENTIFIC INC. (AMEX: MSS),
which develops, manufactures, and markets 'intelligent' computer controlled
injection systems for medical and dental markets, today received notice from the
staff of the American Stock Exchange that it no longer complies with the
Exchange's continued listing standards requiring shareholder equity of at least
$6,000,000, as a result of the losses in its five most recent years, and that
its securities are therefore subject to delisting from the Exchange. The Company
will appeal this determination and request a hearing before a Listing
Qualification Panel. There can be no assurance that the Company's request for
continued listing will be granted.

The Company also today announced that Stuart Wildhorn has resigned his position
as President of the Company effective June 30, 2006. Mr. Wildhorn and his family
have decided to return to Colorado, where he will be taking an executive
position with a medical products manufacturing company.

"We greatly appreciate the contributions that Stu has made to Milestone
Scientific over the past five years," noted Leonard Osser, Chairman and Chief
Executive Officer of the Company. "He has greatly improved the operating
performance of our Dental Division, in particular, and we wish him well in his
future endeavors."

The Company does not intend to hire another executive to fill the position held
by Mr. Wildhorn at the present time. Mr. Wildhorn's duties as President will be
transferred to Tom Ronca, who joined Milestone Scientific Inc. as Chief
Operating Officer in May 2005.

ABOUT MILESTONE SCIENTIFIC, INC.

MILESTONE SCIENTIFIC INC. is the developer, manufacturer and marketer of
CompuMed(R) and CompuDent(R) computer controlled injection systems. These
systems comprise a microprocessor controlled drive unit as well as The Wand(R)
handpiece, a single patient

<PAGE>

use product that is held in a pen-like manner for injections. The Company also
sells the SafetyWand(R), which incorporates engineered sharps injury protection
features to aid in the prevention of accidental needlesticks. Milestone has also
developed proprietary consumer (Ionic White(TM)) and professional (CoolBlue(TM))
teeth whitening systems that were introduced to the market in 2005.

In 2001, Milestone Scientific received broad United States patent protection on
an enabling technology for computer controlled, pressure sensitive infusion,
perfusion, suffusion and aspiration, which provides real time displays of
pressures, fluid densities and flow rates, that advances the delivery and
removal of a wide array of fluids. Development of this CompuFlo technology is
currently underway.

The Company is headquartered in Livingston, New Jersey, and its common stock
trades on the American Stock Exchange under the symbol "MSS".

This press release contains forward-looking statements regarding the timing and
financial impact of the Milestone's ability to implement its business plan,
expected revenues and future success. These statements involve a number of risks
and uncertainties and are based on assumptions involving judgments with respect
to future economic, competitive and market conditions and future business
decisions, all of which are difficult or impossible to predict accurately and
many of which are beyond Milestone's control. Some of the important factors that
could cause actual results to differ materially from those indicated by the
forward-looking statements are general economic conditions, failure to achieve
expected revenue growth, changes in our operating expenses, adverse patent
rulings, FDA or legal developments, competitive pressures, changes in customer
and market requirements and standards, and the risk factors detailed from time
to time in Milestone's periodic filings with the Securities and Exchange
Commission, including without limitation, Milestone's Annual Report on Form
10-KSB for the year ended December 31, 2005. The forward looking-statements in
this press release are based upon management's reasonable belief as of the date
hereof. Milestone undertakes no obligation to revise or update publicly any
forward-looking statements for any reason.


                   For additional information, please contact:
                      Leonard Osser, CEO, at (973) 535-2717


</PRE>
</BODY>
</HTML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----
