<DOCUMENT>
<TYPE>EX-32.2
<SEQUENCE>5
<FILENAME>b414478ex_32-2.txt
<DESCRIPTION>EXHIBIT 32.2
<TEXT>
<PAGE>





                                  EXHIBIT 32.2
                            CERTIFICATION PURSUANT TO
                             18 U.S.C. SECTION 1350,
                             AS ADOPTED PURSUANT TO

SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

In connection with the Quarterly Report of Milestone Scientific Inc. on Form
10-QSB for the six months ending June 30, 2006 as filed with the Securities and
Exchange Commission on the date hereof (the "Report"), I, David Cohn, Chief
Financial Officer of Milestone, certify pursuant to 18 U.S.C. ss. 1350, as
adopted pursuant to ss. 906 of the Sarbanes-Oxley Act of 2002, that: (1) The
Report fully complies with the requirements of section 13(a) or 15(d) of the
Securities Exchange Act of 1934; and (2) The information contained in the Report
fairly presents, in all material respects, the financial condition and result of
operations of Milestone.


                              /s/ David Cohn
                              -----------------------------
                              David Cohn
                              Chief Financial Officer
                              August 14, 2006



</TEXT>
</DOCUMENT>
