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<SEC-DOCUMENT>0000950123-07-007556.txt : 20070516
<SEC-HEADER>0000950123-07-007556.hdr.sgml : 20070516
<ACCEPTANCE-DATETIME>20070516095543
ACCESSION NUMBER:		0000950123-07-007556
CONFORMED SUBMISSION TYPE:	NT 10-Q
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20070331
FILED AS OF DATE:		20070516
DATE AS OF CHANGE:		20070516
EFFECTIVENESS DATE:		20070516

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MILESTONE SCIENTIFIC INC/NJ
		CENTRAL INDEX KEY:			0000855683
		STANDARD INDUSTRIAL CLASSIFICATION:	ORTHOPEDIC, PROSTHETIC & SURGICAL APPLIANCES & SUPPLIES [3842]
		IRS NUMBER:				133545623
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		NT 10-Q
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-14053
		FILM NUMBER:		07856185

	BUSINESS ADDRESS:	
		STREET 1:		220 S ORANGE AVE
		STREET 2:		LIVINGSTON CORPORATE PARK
		CITY:			LIVINGSTON
		STATE:			NJ
		ZIP:			07039
		BUSINESS PHONE:		2013793171

	MAIL ADDRESS:	
		STREET 1:		44 KEAN ROAD
		STREET 2:		220 SOUTH ORANGE AVE
		CITY:			LIVINGSTON
		STATE:			NJ
		ZIP:			07039

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	U S OPPORTUNITY SEARCH INC
		DATE OF NAME CHANGE:	19920703
</SEC-HEADER>
<DOCUMENT>
<TYPE>NT 10-Q
<SEQUENCE>1
<FILENAME>y35095ntnt10vq.htm
<DESCRIPTION>FORM NT 10-Q
<TEXT>
<HTML>
<HEAD>
<TITLE>NT 10-Q</TITLE>
</HEAD>
<BODY bgcolor="#FFFFFF">
<!-- PAGEBREAK -->
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>
<DIV style="font-family: 'Times New Roman',Times,serif">




<DIV align="right">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="20%">

<!-- Begin Table Head -->
<TR valign="bottom">
<TD width="1%">&nbsp;</TD>
<TD width="98%">&nbsp;</TD>
<TD width="1%">&nbsp;</TD>
</TR>

<!-- End Table Head -->
<!-- Begin Table Body -->

<TR valign="bottom">
<TD width="1%" style="border-left: 1px solid #000000; border-top: 1px solid #000000">&nbsp;</TD>
<TD align="center" valign="top" style="border-top: 1px solid #000000">OMB APPROVAL</TD>
<TD width="1%" style="border-right: 1px solid #000000; border-top: 1px solid #000000">&nbsp;</TD>
</TR>

<TR valign="bottom">
<TD width="1%" style="border-left: 1px solid #000000; border-top: 1px solid #000000">&nbsp;</TD>
<TD valign="top" style="border-top: 1px solid #000000"><DIV style="margin-left:0px; text-indent:-0px">OMB Number:&nbsp;3235-0058
</DIV></TD>
<TD width="1%" style="border-right: 1px solid #000000; border-top: 1px solid #000000">&nbsp;</TD>
</TR>

<TR valign="bottom">
<TD width="1%" style="border-left: 1px solid #000000">&nbsp;</TD>
<TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Expires:&nbsp;April&nbsp;30, 2009</DIV></TD>
<TD width="1%" style="border-right: 1px solid #000000">&nbsp;</TD>
</TR>

<TR valign="bottom">
<TD width="1%" style="border-left: 1px solid #000000">&nbsp;</TD>
<TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Estimated average burden
hours per response ... 2.50</DIV></TD>
<TD width="1%" style="border-right: 1px solid #000000">&nbsp;</TD>
</TR>
<TR style="font-size: 1px" valign="bottom">
<TD nowrap align="left" colspan="3" style="border-top: 1px solid #000000">&nbsp;</TD>
</TR>

<!-- End Table Body -->
</TABLE>
</DIV>


<DIV align="right">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="20%">
<!-- Begin Table Head -->
<TR valign="bottom" style="font-size: 2pt">
<TD width="1%">&nbsp;</TD>
<TD width="98%">&nbsp;</TD>
<TD width="1%">&nbsp;</TD>
</TR>
<!-- End Table Head -->
<!-- Begin Table Body -->

<TR valign="bottom">
<TD width="1%" style="border-left: 1px solid #000000; border-top: 1px solid #000000">&nbsp;</TD>
<TD align="center" valign="top" style="border-top: 1px solid #000000">SEC FILE NUMBER</TD>
<TD width="1%" style="border-right: 1px solid #000000; border-top: 1px solid #000000">&nbsp;</TD>
</TR>

<TR valign="bottom">
<TD width="1%" style="border-left: 1px solid #000000">&nbsp;</TD>
<TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;
</DIV></TD>
<TD width="1%" style="border-right: 1px solid #000000">&nbsp;</TD>
</TR>

<TR valign="bottom" style="font-size: 2pt">
<TD width="1%" style="border-top: 1px solid #000000">&nbsp;</TD>
<TD align="center" valign="top" style="border-top: 1px solid #000000">&nbsp;</TD>
<TD width="1%" style="border-top: 1px solid #000000">&nbsp;</TD>
</TR>
<TR valign="bottom">
<TD width="1%" style="border-left: 1px solid #000000; border-top: 1px solid #000000">&nbsp;</TD>
<TD align="center" valign="top" style="border-top: 1px solid #000000">CUSIP NUMBER</TD>
<TD width="1%" style="border-right: 1px solid #000000; border-top: 1px solid #000000">&nbsp;</TD>
</TR>

<TR valign="bottom">
<TD width="1%" style="border-left: 1px solid #000000">&nbsp;</TD>
<TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;
</DIV></TD>
<TD width="1%" style="border-right: 1px solid #000000">&nbsp;</TD>
</TR>

<TR style="font-size: 1px" valign="bottom">
<TD nowrap align="left" colspan="3" style="border-top: 1px solid #000000">&nbsp;</TD>
</TR>

<!-- End Table Body -->
</TABLE>
</DIV>

<DIV align="center" style="font-size: 12pt; margin-top: 1pt"><B>UNITED STATES<BR>
SECURITIES AND EXCHANGE COMMISSION<BR>
Washington, D.C. 20549</B>
</DIV>

<DIV align="center" style="font-size: 14pt; margin-top: 12pt"><B>FORM 12b-25</B>
</DIV>

<DIV align="center" style="font-size: 12pt; margin-top: 12pt"><B>Commission
File Number 001-14053</B>
</DIV>

<DIV align="center" style="font-size: 12pt; margin-top: 12pt"><B>NOTIFICATION OF LATE FILING</B>
</DIV>




<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
<!-- Begin Table Head -->
<TR valign="bottom">
<TD width="10%">&nbsp;</TD>
<TD width="2%">&nbsp;</TD>
<TD width="10%">&nbsp;</TD>
<TD width="8%">&nbsp;</TD>
<TD width="2%">&nbsp;</TD>
<TD width="69%">&nbsp;</TD>
</TR>
<!-- End Table Head -->
<!-- Begin Table Body -->
<TR valign="bottom">
<TD nowrap valign="top"><I>(Check one):</I></TD>
<TD>&nbsp;</TD>
<TD colspan="4" valign="top" align="left">
<FONT face="wingdings">&#111;</FONT>&nbsp; Form&nbsp;10-K
<FONT face="wingdings">&#111;</FONT>&nbsp; Form&nbsp;20-F
<FONT face="wingdings">&#111;</FONT>&nbsp; Form&nbsp;11-K
<FONT face="wingdings">&#254;</FONT>&nbsp; Form&nbsp;10-Q
<FONT face="wingdings">&#111;</FONT>&nbsp; Form&nbsp;10-D
<FONT face="wingdings">&#111;</FONT>&nbsp; Form&nbsp;N-SAR
<FONT face="wingdings">&#111;</FONT>&nbsp; Form&nbsp;N-CSR
</TD>
</TR>
<TR valign="bottom" style="line-height: 6pt"><!-- Blank Space -->
<TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">&nbsp;</TD>
<TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
<TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;
</DIV></TD>
<TD>&nbsp;</TD>
<TD nowrap align="left" valign="top">For Period Ended:</TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top" colspan="2"> March 31, 2007</TD>
</TR>
<TR style="font-size: 1px">
<TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;
</DIV></TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">&nbsp;</TD>
<TD colspan="3" align="left" valign="top" style="border-top: 1px solid #000000">&nbsp;</TD>
</TR>
<TR valign="bottom" style="line-height: 3pt"><!-- Blank Space -->
<TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">&nbsp;</TD>
<TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
<TD valign="top">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD colspan="3" valign="top" align="left">
<FONT face="wingdings">&#111;</FONT>&nbsp;&nbsp; Transition Report on Form&nbsp;10-K</TD>
<TD>&nbsp;</TD>
</TR>
<TR valign="bottom" style="line-height: 3pt"><!-- Blank Space -->
<TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">&nbsp;</TD>
<TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
<TD valign="top">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD colspan="3" valign="top" align="left">
<FONT face="wingdings">&#111;</FONT>&nbsp;&nbsp; Transition Report on Form&nbsp;20-F</TD>
<TD>&nbsp;</TD>
</TR>
<TR valign="bottom" style="line-height: 3pt"><!-- Blank Space -->
<TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">&nbsp;</TD>
<TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
<TD valign="top">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD colspan="3" valign="top" align="left">
<FONT face="wingdings">&#111;</FONT>&nbsp;&nbsp; Transition Report on Form&nbsp;11-K</TD>
<TD>&nbsp;</TD>
</TR>
<TR valign="bottom" style="line-height: 3pt"><!-- Blank Space -->
<TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">&nbsp;</TD>
<TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
<TD valign="top">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD colspan="3" valign="top" align="left">
<FONT face="wingdings">&#111;</FONT>&nbsp;&nbsp; Transition Report on Form&nbsp;10-Q</TD>
<TD>&nbsp;</TD>
</TR>
<TR valign="bottom" style="line-height: 3pt"><!-- Blank Space -->
<TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">&nbsp;</TD>
<TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
<TD valign="top">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD nowrap colspan="3" valign="top" align="left">
<FONT face="wingdings">&#111;</FONT>&nbsp;&nbsp; Transition Report on Form&nbsp;N-SAR</TD>
<TD>&nbsp;</TD>
</TR>
<TR valign="bottom" style="line-height: 6pt"><!-- Blank Space -->
<TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;</DIV></TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">&nbsp;</TD>
<TD>&nbsp;</TD>
</TR>
<TR valign="bottom">
<TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;
</DIV></TD>
<TD>&nbsp;</TD>
<TD colspan="2" align="left" valign="top" nowrap>For the Transition Period Ended:
</TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top"></TD>
<TD>&nbsp;</TD>
</TR>
<TR style="font-size: 1px">
<TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;
</DIV></TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD colspan="2" align="left" valign="top" style="border-top: 1px solid #000000">&nbsp;</TD>
</TR>
<!-- End Table Body -->
</TABLE>
</DIV>
<P>
<DIV style="width: 100%; border: 1px solid black; padding: 12px;">

<DIV align="center" style="font-size: 10pt; margin-top: 6pt"><I>Read Instruction (on back page) Before Preparing Form. Please Print or Type.</I>
</DIV>

<DIV align="center" style="font-size: 10pt"><B>Nothing in this form shall be construed to imply that the Commission has verified any information contained herein.
</B></DIV>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">If the notification relates to a portion of the filing checked above, identify the Item(s) to which
the notification relates: N/A
</DIV>

<!-- link1 "PART I &#151; REGISTRANT INFORMATION" -->
<DIV align="left"><A NAME="000"></A></DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 12pt"><B>PART I &#151; REGISTRANT INFORMATION</B>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 18pt">Milestone Scientific Inc.
<DIV style="border-bottom: 1px solid #000000; font-size: 1px">&nbsp;</DIV>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 2pt">Full Name of Registrant
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 18pt">Not Applicable
<DIV style="border-bottom: 1px solid #000000; font-size: 1px">&nbsp;</DIV>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 2pt">Former Name if Applicable
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 18pt">
<BR>220 South Orange Avenue, Livingston Corporate Park <DIV style="border-bottom: 1px solid #000000; font-size: 1px">&nbsp;</DIV>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 2pt">Address of Principal Executive Office <I>(Street and Number)</I>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 18pt">Livingston, NJ 07039
<DIV style="border-bottom: 1px solid #000000; font-size: 1px">&nbsp;</DIV>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 2pt">City, State and Zip Code
</DIV>
<P align="center" style="font-size: 10pt"><!-- Folio --><!-- /Folio -->
</DIV>

<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>
<DIV style="font-family: 'Times New Roman',Times,serif">

<!-- link1 "PART II &#151; RULES 12b-25(b) AND (c)" -->

<DIV align="left" style="font-size: 10pt; margin-top: 12pt"><B>PART II &#151; RULES 12b-25(b) AND (c)</B>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">If the subject report could not be filed without unreasonable effort or expense and the registrant seeks relief pursuant to Rule&nbsp;12b-25(b), the following should be completed. (Check box
if appropriate.)
</DIV>

<DIV align="center">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="100%">
<!-- Begin Table Head -->
<TR valign="bottom">
<TD width="5%">&nbsp;</TD>
<TD width="1%">&nbsp;</TD><!-- VRule -->
<TD width="1%">&nbsp;</TD>
<TD width="3%">&nbsp;</TD>
<TD width="2%">&nbsp;</TD>
<TD width="88%">&nbsp;</TD>
</TR>
<!-- End Table Head -->
<!-- Begin Table Body -->

<TR valign="bottom">
<TD valign="middle" rowspan="5"><DIV style="margin-left:15px; text-indent:-0px">
<FONT face="wingdings">&#254;</FONT></DIV></TD>
</TR>

<TR valign="bottom">
<TD style="border-right: 1px solid #000000">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">(a)
</TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">The reason described in reasonable detail in Part III of this form could not be
eliminated without unreasonable effort or expense</TD>
</TR>


<TR valign="bottom" style="line-height: 3pt"><!-- Blank Space -->
<TD style="border-right: 1px solid #000000">&nbsp;</TD>
<TD align="left" valign="top">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">&nbsp;</TD>
</TR>

<TR valign="bottom">
<TD style="border-right: 1px solid #000000">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">(b)
</TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">
The subject annual report, semi-annual report, transition report on Form&nbsp;10-K, Form&nbsp;20-F, Form&nbsp;11-K, Form&nbsp;N-SAR or Form&nbsp;N-CSR, or portion thereof, will be filed on or before the fifteenth calendar day following the
prescribed due date; or the subject quarterly report or transition report on Form&nbsp;10-Q or subject distribution report on Form&nbsp;10-D, or portion thereof, will be filed on or before the fifth calendar day following the prescribed due date;
and
</TD>
</TR>
<TR valign="bottom" style="line-height: 3pt"><!-- Blank Space -->
<TD style="border-right: 1px solid #000000">&nbsp;</TD>
<TD align="left" valign="top">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">&nbsp;</TD>
</TR>

<TR valign="bottom">
<TD>&nbsp;</TD>
<TD style="border-right: 1px solid #000000">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">(c)
</TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">The accountant&#146;s statement or other exhibit required by Rule&nbsp;12b-25(c) has been attached if applicable.
</TD>
</TR>
<!-- End Table Body -->
</TABLE>
</DIV>


<!-- link1 "PART III &#151; NARRATIVE" -->

<DIV align="left" style="font-size: 10pt; margin-top: 12pt"><B>PART III &#151; NARRATIVE</B>
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">State
below in reasonable detail the reasons why Forms 10-K, 20-F, 11-K, 10-Q, 10-D, N-SAR, N-CSR, or the transition report or portion thereof, could not be filed within the prescribed time period.
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">Due to the loss of a senior accounting officer, the registrant&#146;s chief financial officer could not complete his performance of the necessary review procedures to provide the
certifications mandated under sections 302 and 906 of the Sarbanes-Oxley Act of 2002 for the quarter ended March 31, 2007 by May 15, 2007 without unreasonable effort or expense.  The registrant believes that the quarterly report on Form 10-QSB for
such period will be available for filing on or before May 21, 2007.</DIV>

<P align="center" style="font-size: 10pt"><!-- Folio -->2<!-- /Folio -->


</Div>
<!-- PAGEBREAK -->
<P><HR noshade><P>
<H5 align="left" style="page-break-before:always">&nbsp;</H5><P>
<DIV style="font-family: 'Times New Roman',Times,serif">


<DIV align="left" style="margin-top: 12pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt; background: transparent; color: #000000">
<TR>
<TD width="15%"></TD>
<TD width="1%"></TD>
<TD width="84"></TD>
</TR>
<TR valign="top">
<TD valign="middle" nowrap align="left">SEC 1344 (03-05)</TD>
<TD>&nbsp;</TD>
<TD><B>Persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
</B></TD>
</TR>
</TABLE>
</DIV>


<DIV align="center" style="font-size: 10pt; margin-top: 6pt">(Attach
extra Sheets if Needed)</DIV>

<!-- link1 "PART IV &#151; OTHER INFORMATION" -->
<DIV align="center" style="font-size: 10pt; margin-top: 0pt"><B>PART IV &#151; OTHER INFORMATION</B>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
<TD width="3%" nowrap align="left">(1)</TD>
<TD width="1%">&nbsp;</TD>
<TD>Name and telephone number of person to contact in regard to this notification</TD>
</TR>
</TABLE>
</DIV>
<DIV align="right">
<TABLE style="font-size: 10pt" cellspacing="0" border="0" cellpadding="0" width="96%">
<!-- Begin Table Head -->
<TR valign="bottom">
<TD width="47%">&nbsp;</TD>
<TD width="5%">&nbsp;</TD>
<TD width="8%">&nbsp;</TD>
<TD width="5%">&nbsp;</TD>
<TD width="35%">&nbsp;</TD>
</TR>
<!-- End Table Head -->
<!-- Begin Table Body -->
<TR style="font-size: 10pt">
<TD align="center" valign="top" style="border-bottom: 1px solid #000000">David Cohn &nbsp;</TD>
<TD>&nbsp;</TD>
<TD align="center" valign="top" style="border-bottom: 1px solid #000000">(973)&nbsp;</TD>
<TD>&nbsp;</TD>
<TD align="center" valign="top" style="border-bottom: 1px solid #000000">535-2717&nbsp;</TD>
</TR>
<TR valign="bottom">
<TD valign="top" align="center"><DIV style="margin-left:0px; text-indent:-0px">(Name)</DIV></TD>
<TD>&nbsp;</TD>
<TD nowrap align="center" valign="bottom">(Area Code)
</TD>
<TD>&nbsp;</TD>
<TD align="center" valign="bottom">(Telephone Number)</TD>
</TR>
<!-- End Table Body -->
</TABLE>
</DIV>


<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
<TD width="3%" nowrap align="left">(2)</TD>
<TD width="1%">&nbsp;</TD>
<TD>Have all other periodic reports required under Section&nbsp;13 or 15(d) of the Securities Exchange Act of 1934 or Section&nbsp;30 of the Investment Company Act of 1940 during the preceding 12&nbsp;months or for such shorter period that the
registrant was required to file such report(s) been filed? If answer is no, identify report(s).
</TD>
</TR>
<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent; margin-top: 1pt">
<TD width="3%" nowrap align="left">&nbsp;</TD>
<TD width="1%">&nbsp;</TD>
<TD align="right">Yes&nbsp;<FONT face="wingdings">&#254;</FONT>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;No&nbsp;<FONT face="wingdings">&#111;</FONT>
</TD>
</TR>

<TR>
<TD style="font-size: 6pt">&nbsp;</TD>
</TR>

</TABLE>
</DIV>

<DIV style="font-size: 10pt; margin-left: 4%"><DIV style="border-bottom: 1px solid #000000; font-size: 10pt">

</DIV>
</DIV>

<DIV style="margin-top: 6pt">
<TABLE width="100%" border="0" cellpadding="0" cellspacing="0" style="font-size: 10pt">

<TR valign="top" style="font-size: 10pt; color: #000000; background: transparent">
<TD width="3%" nowrap align="left">(3)</TD>
<TD width="1%">&nbsp;</TD>
<TD>Is it anticipated that any significant change in results of
operations for the corresponding period for the last fiscal year will be reflected by the earnings statements to be included in the subject report or portion thereof?
</TD>
</TR>
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<TD align="right">Yes&nbsp;<FONT face="wingdings">&#111;</FONT>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;No&nbsp;<FONT face="wingdings">&#254;</FONT>
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<TD width="3%" nowrap align="left">&nbsp;</TD>
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<TD>If so, attach an explanation of the anticipated change, both narratively and quantitatively, and, if appropriate, state the reasons why a reasonable estimate of the results cannot be made.
</TD>
</TR>
<TR>
<TD style="font-size: 6pt">&nbsp;</TD>
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<DIV align="center" style="font-size: 10pt; margin-top: 12pt"><DIV style="border-bottom: 3px solid #000000; font-size: 1px">&nbsp;
</DIV>
</DIV>



<DIV align="center" style="font-size: 10pt; margin-top: 24pt"><DIV style="border-bottom: 1px solid #000000; font-size: 10pt; width: 75%">Milestone Scientific, Inc.&nbsp;
</DIV>
</DIV>

<DIV align="center" style="font-size: 10pt; margin-top: 2pt">(Name of Registrant as Specified in Charter)
</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">Has caused this notification to be signed on its behalf by the undersigned hereunto duly authorized.
</DIV>

<DIV align="center">
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<TD width="3%">&nbsp;</TD>
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<TD width="36%">&nbsp;</TD>
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<TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">Date
</DIV></TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">05/15/07</TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">By:</TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top"> /s/ David Cohn </TD>
</TR>
<TR style="font-size: 1px">
<TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;
</DIV></TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top" style="border-top: 1px solid #000000">&nbsp;
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<TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;
</DIV></TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">Name: David Cohn</TD>
</TR>
<TR valign="bottom">
<TD valign="top"><DIV style="margin-left:0px; text-indent:-0px">&nbsp;
</DIV></TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">&nbsp;</TD>
<TD>&nbsp;</TD>
<TD align="left" valign="top">Title: Chief Financial Officer</TD>
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</DIV>


<DIV align="left" style="font-size: 10pt; margin-top: 6pt">
Instruction: The form may be signed by an executive officer of the
registrant or by any other duly authorized representative.
The name and title of the person signing the form shall be typed or printed
beneath the signature. If the statement is signed on behalf of the registrant by an
authorized representative (other than an executive officer), evidence of the representative&#146;s
authority to sign on behalf of the registrant shall be filed with the form.
</DIV>

<DIV align="CENTER" style="font-size: 10pt; margin-top: 6pt"><B>ATTENTION</B></DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">Intentional misstatements or omissions of fact
constitute Federal criminal violations. (See 18 U.S.C. 1001)</DIV>
<DIV align="CENTER" style="font-size: 10pt; margin-top: 6pt"><B>GENERAL INSTRUCTIONS</B></DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">1. This form is required by Rule 12b-25 of the General
Rules and Regulations under the Securities Exchange Act of 1934.</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">2. One signed original and four
conformed copies of this form and amendments thereto must be completed and filed with the Securities and Exchange Commission, Washington, D.C. 20549, in accordance with Rule 0-3 of the General Rules and Regulations under the Act. The information
contained in or filed
with the form will be made a matter of public record in the Commission files.</DIV>

<DIV align="left" style="font-size: 10pt; margin-top: 6pt">3. A manually signed copy of the form and
amendments thereto shall be filed with each national securities
exchange on which any class of securities of the registrant is registered.</DIV>
<DIV align="left" style="font-size: 10pt; margin-top: 6pt">4. Amendments to
the notifications must also be filed on form 12b-25 but need not restate information that has been correctly furnished.
The form shall be clearly identified as an amended notification.</DIV>
<DIV align="left" style="font-size: 10pt; margin-top: 6pt">5. Electronic filers.
This form shall not be used by electronic filers unable to timely file a report solely due to electronic
difficulties. Filers unable to submit a report within the time period prescribed due to difficulties in
electronic filing should comply with either Rule 201 or Rule 202 of Regulation S-T or apply for
an adjustment in filing date pursuant to Rule 13(b) of  Regulation S-T. </DIV>

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