<SEC-DOCUMENT>0001193125-16-542842-index.html : 20160415
<SEC-HEADER>0001193125-16-542842.hdr.sgml : 20160415
<ACCEPTANCE-DATETIME>20160415124434
ACCESSION NUMBER:		0001193125-16-542842
CONFORMED SUBMISSION TYPE:	DEF 14A
PUBLIC DOCUMENT COUNT:		4
CONFORMED PERIOD OF REPORT:	20150525
FILED AS OF DATE:		20160415
DATE AS OF CHANGE:		20160415
EFFECTIVENESS DATE:		20160415

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MILESTONE SCIENTIFIC INC.
		CENTRAL INDEX KEY:			0000855683
		STANDARD INDUSTRIAL CLASSIFICATION:	ORTHOPEDIC, PROSTHETIC & SURGICAL APPLIANCES & SUPPLIES [3842]
		IRS NUMBER:				133545623
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		DEF 14A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-14053
		FILM NUMBER:		161573812

	BUSINESS ADDRESS:	
		STREET 1:		220 SOUTH ORANGE AVENUE
		CITY:			LIVINGSTON
		STATE:			NJ
		ZIP:			07039
		BUSINESS PHONE:		(973) 535-2717

	MAIL ADDRESS:	
		STREET 1:		220 SOUTH ORANGE AVENUE
		CITY:			LIVINGSTON
		STATE:			NJ
		ZIP:			07039

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	MILESTONE SCIENTIFIC INC/NJ
		DATE OF NAME CHANGE:	19970409

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	U S OPPORTUNITY SEARCH INC
		DATE OF NAME CHANGE:	19920703
</SEC-HEADER>
<DOCUMENT>
<TYPE>DEF 14A
<SEQUENCE>1
<FILENAME>d120378ddef14a.htm
<DESCRIPTION>DEF 14A
<TEXT>
Document 1 - file: d120378ddef14a.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>g120378appcpg02a.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 2 - file: g120378appcpg02a.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>g120378appcpg02b.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 3 - file: g120378appcpg02b.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>g120378appcpg02c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: g120378appcpg02c.jpg

</DOCUMENT>
</SEC-DOCUMENT>