    <SEC-DOCUMENT>0001437749-17-015601-index.html : 20170906
    <SEC-HEADER>0001437749-17-015601.hdr.sgml : 20170906
    <ACCEPTANCE-DATETIME>20170906080018
    ACCESSION NUMBER:		0001437749-17-015601
    CONFORMED SUBMISSION TYPE:	8-K
    PUBLIC DOCUMENT COUNT:		26
    CONFORMED PERIOD OF REPORT:	20170906
    ITEM INFORMATION:		Other Events
    ITEM INFORMATION:		Financial Statements and Exhibits
    FILED AS OF DATE:		20170906
    DATE AS OF CHANGE:		20170906

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			MILESTONE SCIENTIFIC INC.
    		CENTRAL INDEX KEY:			0000855683
    		STANDARD INDUSTRIAL CLASSIFICATION:	ORTHOPEDIC, PROSTHETIC & SURGICAL APPLIANCES & SUPPLIES [3842]
    		IRS NUMBER:				133545623
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		8-K
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-14053
    		FILM NUMBER:		171070221

    	BUSINESS ADDRESS:
    		STREET 1:		220 SOUTH ORANGE AVENUE
    		CITY:			LIVINGSTON
    		STATE:			NJ
    		ZIP:			07039
    		BUSINESS PHONE:		(973) 535-2717

    	MAIL ADDRESS:
    		STREET 1:		220 SOUTH ORANGE AVENUE
    		CITY:			LIVINGSTON
    		STATE:			NJ
    		ZIP:			07039

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	MILESTONE SCIENTIFIC INC/NJ
    		DATE OF NAME CHANGE:	19970409

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	U S OPPORTUNITY SEARCH INC
    		DATE OF NAME CHANGE:	19920703
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>8-K
    <SEQUENCE>1
    <FILENAME>mlss20170830_8k.htm
    <DESCRIPTION>FORM 8-K
    <TEXT>
    Document 1 - file: mlss20170830_8k.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>EX-99.1
    <SEQUENCE>2
    <FILENAME>ex99-1.htm
    <DESCRIPTION>EXHIBIT 99.1
    <TEXT>
    Document 2 - file: ex99-1.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>ex99-1img048.jpg
    <TEXT>
    Document 3 - file: ex99-1img048.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>ex99-1img047.jpg
    <TEXT>
    Document 4 - file: ex99-1img047.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>ex99-1img046.jpg
    <TEXT>
    Document 5 - file: ex99-1img046.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>6
    <FILENAME>ex99-1img045.jpg
    <TEXT>
    Document 6 - file: ex99-1img045.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>ex99-1img044.jpg
    <TEXT>
    Document 7 - file: ex99-1img044.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>ex99-1img043.jpg
    <TEXT>
    Document 8 - file: ex99-1img043.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>ex99-1img042.jpg
    <TEXT>
    Document 9 - file: ex99-1img042.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>ex99-1img041.jpg
    <TEXT>
    Document 10 - file: ex99-1img041.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>11
    <FILENAME>ex99-1img040.jpg
    <TEXT>
    Document 11 - file: ex99-1img040.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>12
    <FILENAME>ex99-1img039.jpg
    <TEXT>
    Document 12 - file: ex99-1img039.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>13
    <FILENAME>ex99-1img038.jpg
    <TEXT>
    Document 13 - file: ex99-1img038.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>14
    <FILENAME>ex99-1img037.jpg
    <TEXT>
    Document 14 - file: ex99-1img037.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>15
    <FILENAME>ex99-1img036.jpg
    <TEXT>
    Document 15 - file: ex99-1img036.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>16
    <FILENAME>ex99-1img035.jpg
    <TEXT>
    Document 16 - file: ex99-1img035.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>17
    <FILENAME>ex99-1img034.jpg
    <TEXT>
    Document 17 - file: ex99-1img034.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>18
    <FILENAME>ex99-1img033.jpg
    <TEXT>
    Document 18 - file: ex99-1img033.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>19
    <FILENAME>ex99-1img032.jpg
    <TEXT>
    Document 19 - file: ex99-1img032.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>20
    <FILENAME>ex99-1img031.jpg
    <TEXT>
    Document 20 - file: ex99-1img031.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>21
    <FILENAME>ex99-1img030.jpg
    <TEXT>
    Document 21 - file: ex99-1img030.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>22
    <FILENAME>ex99-1img029.jpg
    <TEXT>
    Document 22 - file: ex99-1img029.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>23
    <FILENAME>ex99-1img028.jpg
    <TEXT>
    Document 23 - file: ex99-1img028.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>24
    <FILENAME>ex99-1img027.jpg
    <TEXT>
    Document 24 - file: ex99-1img027.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>25
    <FILENAME>ex99-1img026.jpg
    <TEXT>
    Document 25 - file: ex99-1img026.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>26
    <FILENAME>ex99-1img025.jpg
    <TEXT>
    Document 26 - file: ex99-1img025.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>