XML 74 R62.htm IDEA: XBRL DOCUMENT v3.8.0.1

Note R - Commitments and Other (Details Textual)			1 Months Ended		12 Months Ended
	Oct. 02, 2017 USD ($) $ / shares shares	Jan. 01, 2005 shares	Mar. 31, 2018 USD ($)	Feb. 28, 2018 USD ($)	Dec. 31, 2017 USD ($) ft²	Dec. 31, 2016 USD ($)
Area of Office Space | ft²					7,625
Operating Leases, Rent Expense, Minimum Rentals					$ 12,522
Operating Leases, Rent Expense					141,428	$ 133,657
Payments for Postemployment Benefits					$ 203,111	203,111
Define Benefit Plan, Payment Period					5 years
Additional Percentage of Director Compensation on Sales Value Using Certain Specify Technology		2.50%
Additional Percentage of Director Compensation Sales Value Using Other Kind of Technology		5.00%
Consulting Services [Member]
Related Party Transaction, Expenses from Transactions with Related Party					$ 100,000	100,000
Innovest S.p.A. [Member] | Consulting Services [Member]
Related Party Transaction, Expenses from Transactions with Related Party					80,000
Director of Clinical Affairs [Member]
Stock Issued During Period, Shares, Stock Options Exercised, Attributable to Consultants | shares		8,333
Royalty Expense					554,150	526,737
Professional Fees					$ 275,000	$ 275,000
Former CEO [Member]
Employee Resignation Assertion, Basic Salary for One Year	$ 300,000
Employee Resignation Assertion, Health and Disability Insurance for One Year	30,000
Employee Resignation Assertion, Car Allowance for One Year	$ 1,200
Employee Resignation Assertion, Vesting Term After Resignation	90 days
Employee Resignation Assertion, Number of Options Vested | shares	921,942
Employee Resignation Assertion, Options Exercise Price | $ / shares	$ 2
Former CEO [Member] | Subsequent Event [Member]
Employee Resignation Assertion, Gross Settlement				$ 175,000
Employee Resignation Assertion, Payment			$ 75,000

X

- Definition

Additional payment to director as percentage of sales value using certain specify technology.

+ References

No definition available.

+ Details

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X

- Definition

Additional payment to director as percentage of sales value using other kind of technology.

+ References

No definition available.

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X

- Definition

Area of office space.

+ References

No definition available.

+ Details

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X

- Definition

Defined benefit plan payment period.

+ References

No definition available.

+ Details

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X

- Definition

The amount of basic salary would be paid to a resigned employee for one year according to the his or her assertion.

+ References

No definition available.

+ Details

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X

- Definition

The amount of car allowance will be paid to a resigned employee for one year according to the his or her assertion.

+ References

No definition available.

+ Details

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X

- Definition

Amount of the gross settlement in connection to a employee resignation.

+ References

No definition available.

+ Details

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Balance Type:	credit
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X

- Definition

The amount of health and disability insurance would be paid in behalf of a resigned employee for one year according to the his or her assertion.

+ References

No definition available.

+ Details

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X

- Definition

The number of options would be vested immediate according to a resigned employee's assertion.

+ References

No definition available.

+ Details

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Data Type:	xbrli:sharesItemType
Balance Type:	na
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X

- Definition

The exercise price of options according to a resigned employee's assertion.

+ References

No definition available.

+ Details

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X

- Definition

Amount of payment in connection to an employee resignation.

+ References

No definition available.

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X

- Definition

The versing term for options according to a employees's assertion.

+ References

No definition available.

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- Definition

Stock issued during period shares stock options exercised attributable to consultants.

+ References

No definition available.

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X

- Definition

Amount of rent expense incurred for leased assets, including but not limited to, furniture and equipment, that is not directly or indirectly associated with the manufacture, sale or creation of a product or product line.

+ References

No definition available.

+ Details

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Data Type:	xbrli:monetaryItemType
Balance Type:	debit
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X

- Definition

This element represents the payments that the lessee is obligated to make or can be required to make in connection with a property under the terms of an agreement classified as an operating lease, excluding contingent rentals and a guarantee by the lessee of the lessor's debt and the lessee's obligation to pay (apart from the rental payments) executory costs such as insurance, maintenance, and taxes.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 840
-SubTopic 20
-Section 50
-Paragraph 1
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- Definition

Cash outflows for payments of postemployment benefits (such as severance pay and health insurance benefits) recognized during the period. Postemployment benefits are benefits paid to employees after employment but before retirement.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 45
-Paragraph 25
-Subparagraph (g)
-URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3536-108585

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- Definition

A fee charged for services from professionals such as doctors, lawyers and accountants. The term is often expanded to include other professions, for example, pharmacists charging to maintain a medicinal profile of a client or customer.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 946
-SubTopic 225
-Section S99
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- Definition

Expenses recognized resulting from transactions (excluding transactions that are eliminated in consolidated or combined financial statements) with related party.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
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-SubTopic 10
-Section 50
-Paragraph 1
-Subparagraph (c)
-URI http://asc.fasb.org/extlink&oid=6457730&loc=d3e39549-107864

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- Definition

Amount of expense related to royalty payments under a contractual arrangement such as payment for mineral and drilling rights and use of technology or intellectual property.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 225
-SubTopic 10
-Section S99
-Paragraph 2
-Subparagraph (SX 210.5-03.3)
-URI http://asc.fasb.org/extlink&oid=63488584&loc=d3e20235-122688

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- Details

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- Details

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- Details

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- Details

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