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Note 7 - Patents - Summary of Patents (Details) - USD ($) | Jun. 30, 2019 | Dec. 31, 2018
--- | --- | ---
Patents, cost | $ 1,377,863 | $ 4,017,510
Patents, impairment |  | (1,539,794)
Patents, accumulated amortization | (969,096) | (2,042,443)
Patents, net | 408,767 | 435,273
Foundation Intellectual Property Patents [Member] |  |
Patents, cost | 1,377,863 | 1,377,863
Patents, impairment |  |
Patents, accumulated amortization | (969,096) | (942,590)
Patents, net | $ 408,767 | 435,273
Epidural-Apad Patents [Member] |  |
Patents, cost |  | 2,639,647
Patents, impairment |  | (1,539,794)
Patents, accumulated amortization |  | (1,099,853)
Patents, net |  |

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- Definition Accumulated amount of amortization of assets, excluding financial assets and goodwill, lacking physical substance with a finite life. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 350 -SubTopic 30 -Section 50 -Paragraph 2 -Subparagraph (a)(1) -URI http://asc.fasb.org/extlink&oid=66006027&loc=d3e16323-109275 + Details
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