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Note 7 - Patents (Tables)
9 Months Ended
Sep. 30, 2019
Notes Tables  
Schedule of Finite-Lived Intangible Assets [Table Text Block]
   
September 30, 2019
 
   
Cost
   
Impairment
   
Accumulated Amortization
   
Net
 
Patents-foundation intellectual property
  $
1,377,863
    $
-
    $
(982,349
)   $
395,514
 
Total
  $
1,377,863
    $
-
    $
(982,349
)   $
395,514
 
   
December 31, 2018
 
   
Cost
   
Impairment
   
Accumulated Amortization
   
Net
 
Patents-foundation intellectual property
  $
1,377,863
    $
-
    $
(942,590
)   $
435,273
 
Epidural-Apad acquired patents
   
2,639,647
     
(1,539,794
)    
(1,099,853
)    
-
 
Total
  $
4,017,510
    $
(1,539,794
)   $
(2,042,443
)   $
435,273