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Supplemental Balance Sheet Information - Property and Equipment, Net (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended		12 Months Ended
	Sep. 30, 2017	Sep. 30, 2016	Sep. 30, 2017	Sep. 30, 2016	Dec. 31, 2016	Dec. 31, 2015
Property, Plant and Equipment [Line Items]
Property and equipment, gross	$ 1,835		$ 1,835		$ 1,120	$ 822
Less: accumulated depreciation	(776)		(776)		(617)	(437)
Property and equipment, net	1,059		1,059		503	385
Depreciation and amortization	70	$ 46	159	$ 132	180	133
Scientific equipment
Property, Plant and Equipment [Line Items]
Property and equipment, gross	1,586		1,586		993	627
Leasehold improvements
Property, Plant and Equipment [Line Items]
Property and equipment, gross	192		192		57	57
Furniture and fixtures
Property, Plant and Equipment [Line Items]
Property and equipment, gross	31		31		27	17
Computers and software
Property, Plant and Equipment [Line Items]
Property and equipment, gross	26		26		26	14
Construction in process
Property, Plant and Equipment [Line Items]
Property and equipment, gross	$ 0		$ 0		$ 17	$ 107

X

- Definition

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 360
-SubTopic 10
-Section 50
-Paragraph 1
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- Definition

The aggregate net amount of depreciation, amortization, and accretion recognized during an accounting period. As a noncash item, the net amount is added back to net income when calculating cash provided by or used in operations using the indirect method.

+ References

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Amount before accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

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Amount after accumulated depreciation, depletion and amortization of physical assets used in the normal conduct of business to produce goods and services and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, and furniture and fixtures.

+ References

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