STATEMENTS OF OPERATIONS - USD ($) $ in Thousands	3 Months Ended	9 Months Ended	12 Months Ended
Sep. 30, 2017	Sep. 30, 2016	Sep. 30, 2017	Sep. 30, 2016	Dec. 31, 2016	Dec. 31, 2015
Revenue:
Collaboration revenue	$ 2,497	$ 0	$ 7,624	$ 0	$ 690	$ 0
Grant income	0	0	0	346	346	2,388
Total revenue	2,497	0	7,624	346	1,036	2,388
Operating expenses:
Research and development expense	3,502	2,413	11,279	8,329	13,659	10,124
General and administrative expense	1,270	849	4,806	2,736	3,539	5,408
Total operating expenses	4,772	3,262	16,085	11,065	17,198	15,532
Operating loss	(2,275)	(3,262)	(8,461)	(10,719)	(16,162)	(13,144)
Other income (expense), net:
Interest expense	(201)	(208)	(616)	(516)	(724)	0
Other income (loss), net	163	(56)	140	(64)	(55)	(7)
Total other income (loss), net	(38)	(264)	(476)	(580)	(779)	(7)
Net loss	$ (2,313)	$ (3,526)	$ (8,937)	$ (11,299)	$ (16,941)	$ (13,151)
Basic and diluted loss per common share	$ (1.34)	$ (36.09)	$ (48.73)	$ (103.15)	$ (74.16)	$ (121.63)
Basic and diluted weighted-average common shares outstanding	1,725,906	97,691	183,395	109,539	228,447	108,123

The amount of net income or loss for the period per each share in instances when basic and diluted earnings per share are the same amount and reported as a single line item on the face of the financial statements. Basic earnings per share is the amount of net income or loss for the period per each share of common stock or unit outstanding during the reporting period. Diluted earnings per share includes the amount of net income or loss for the period available to each share of common stock or common unit outstanding during the reporting period and to each share or unit that would have been outstanding assuming the issuance of common shares or units for all dilutive potential common shares or units outstanding during the reporting period.

No definition available.