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Collaborative Research and License Agreements (Details) |  |  | 3 Months Ended | 6 Months Ended |  |
--- | --- | --- | --- | --- | --- | ---
Nov. 13, 2019 USD ($) agreement | Feb. 17, 2019 USD ($) | Jun. 30, 2021 USD ($) | Jun. 30, 2020 USD ($) | Jun. 30, 2021 USD ($) | Jun. 30, 2020 USD ($) | Dec. 31, 2020 USD ($) | Dec. 31, 2019 USD ($)
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |
Collaboration revenue |  |  | $ 79,000 | $ 4,847,000 | $ 1,076,000 | $ 14,030,000 |  |
Deferred revenue, current |  |  | 7,267,000 |  | 7,267,000 |  | $ 8,343,000 |
AbbVie Collaboration | Collaboration Arrangement |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |
Number of collaboration programs | agreement | 2 |  |  |  |  |  |  |
Non-refundable upfront payment received for research agreement | $ 25,000,000 |  |  |  |  |  |  |
Collaboration option exercise fee | 10,000,000 |  |  |  |  |  |  |
Collaboration option exercise fee | $ 10,000,000 |  |  |  |  |  |  |
Termination period upon written notice | 90 days |  |  |  |  |  |  |
Collaboration revenue |  |  | 79,000 | 4,833,000 | 1,076,000 | 13,949,000 |  |
Deferred revenue, current |  |  | 7,267,000 |  | 7,267,000 |  | $ 8,343,000 |
Dermelix License Agreement | Collaboration Arrangement |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |
Non-refundable upfront payment received for research agreement |  | $ 1,000,000 |  |  |  |  |  |
Collaboration revenue |  |  | $ 0 | $ 14,000 | $ 0 | $ 81,000 |  |
Collaboration development expenses |  | $ 1,000,000 |  |  |  |  |  |
Deferred revenue |  |  |  |  |  |  |  | $ 0
Development and Commercialization License | AbbVie Collaboration | Collaboration Arrangement |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |
Collaboration option exercise fee | $ 15,000,000 |  |  |  |  |  |  |
Maximum | AbbVie Collaboration | Collaboration Arrangement |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |
Development milestone payment | 55,000,000 |  |  |  |  |  |  |
Product approval and launch milestone payment | 132,500,000 |  |  |  |  |  |  |
Sales milestone payment | $ 175,000,000 |  |  |  |  |  |  |

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