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Description of Business and Basis of Presentation (Details) $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2021 USD ($) | Sep. 30, 2021 USD ($)
Unusual Risk or Uncertainty [Line Items] |  |
Accumulated deficit generated, since inception | $ (175,079) | $ (175,079)
COVID-19 |  |
Unusual Risk or Uncertainty [Line Items] |  |
Percentage of R&D staff on site | 100.00% |
Percentage of time that office and general and administrative staff are on site | 50.00% |
AbbVie Collaboration | Collaboration Arrangement |  |
Unusual Risk or Uncertainty [Line Items] |  |
Cumulative catch-up adjustment to revenue |  | $ (3,404)
Cumulative catch-up adjustments to revenue, change in estimate | $ (4,480) |

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- Definition Amount of increase (decrease) in revenue recognized for cumulative catch-up adjustment from change in estimate of transaction price which (increases) decreases obligation to transfer good or service to customer for which consideration from customer has been received or is due. Includes, but is not limited to, change in assessment of whether estimate of variable consideration is constrained. + References Reference 1: http://www.xbrl.org/2003/role/exampleRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 50 -Paragraph 10 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=123351226&loc=SL49130551-203045 + Details
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- Definition Office And General And Administrative Staff On Site, Percentage + References No definition available. + Details
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