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Description of Business and Basis of Presentation (Details)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2021
USD ($)
Sep. 30, 2021
USD ($)
Unusual Risk or Uncertainty [Line Items]    
Accumulated deficit generated, since inception $ (175,079) $ (175,079)
COVID-19    
Unusual Risk or Uncertainty [Line Items]    
Percentage of R&D staff on site 100.00%  
Percentage of time that office and general and administrative staff are on site 50.00%  
AbbVie Collaboration | Collaboration Arrangement    
Unusual Risk or Uncertainty [Line Items]    
Cumulative catch-up adjustment to revenue   $ (3,404)
Cumulative catch-up adjustments to revenue, change in estimate $ (4,480)