<SEC-DOCUMENT>0000899243-23-007145.txt : 20230306
<SEC-HEADER>0000899243-23-007145.hdr.sgml : 20230306
<ACCEPTANCE-DATETIME>20230306141900
ACCESSION NUMBER:		0000899243-23-007145
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20230224
FILED AS OF DATE:		20230306
DATE AS OF CHANGE:		20230306

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Lee Hyukku
		CENTRAL INDEX KEY:			0001965063

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-39011
		FILM NUMBER:		23708527

	MAIL ADDRESS:	
		STREET 1:		2430 N. HALSTED ST.
		CITY:			CHICAGO
		STATE:			IL
		ZIP:			60614

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			EXICURE, INC.
		CENTRAL INDEX KEY:			0001698530
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				815333008
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		2430 N. HALSTED ST.
		CITY:			CHICAGO
		STATE:			IL
		ZIP:			60614
		BUSINESS PHONE:		847-673-1700

	MAIL ADDRESS:	
		STREET 1:		2430 N. HALSTED ST.
		CITY:			CHICAGO
		STATE:			IL
		ZIP:			60614

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Max-1 Acquisition Corp
		DATE OF NAME CHANGE:	20170221
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<TYPE>3
<SEQUENCE>1
<FILENAME>doc3.xml
<DESCRIPTION>FORM 3 SUBMISSION
<TEXT>
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<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2023-02-24</periodOfReport>

    <noSecuritiesOwned>1</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001698530</issuerCik>
        <issuerName>EXICURE, INC.</issuerName>
        <issuerTradingSymbol>XCUR</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001965063</rptOwnerCik>
            <rptOwnerName>Lee Hyukku</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O EXICURE, INC., 2430 N. HALSTED ST.</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>CHICAGO</rptOwnerCity>
            <rptOwnerState>IL</rptOwnerState>
            <rptOwnerZipCode>60614</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <footnotes></footnotes>

    <remarks>Exhibit List - Exhibit 24 - Power of Attorney</remarks>

    <ownerSignature>
        <signatureName>/s/ Jonathan Park, Attorney-in-Fact</signatureName>
        <signatureDate>2023-03-03</signatureDate>
    </ownerSignature>
</ownershipDocument>
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<TYPE>EX-24
<SEQUENCE>2
<FILENAME>attachment1.htm
<DESCRIPTION>EX-24 DOCUMENT
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<HEAD>
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<PRE>
                                POWER OF ATTORNEY

      Know all by these present, that the undersigned does hereby constitute
and appoint Matthias Schroff, Elias Papadimas, John Harrington, Jonathan Park,
Samuel Toth, Brittany Stevenson, Caroline Mills and Michael Mosholder, and each
of them, as the undersigned's true and lawful attorneys-in-fact and agents to
do any and all things, and execute any or all instruments which, after the
advice of counsel, said attorneys and agents may deem necessary and advisable
to enable the undersigned to comply with the Securities Exchange Act of 1934,
as amended, and any rules, regulations and requirements of the Securities and
Exchange Commission ("SEC"), including specifically, but without limitation
thereof, power of attorney to sign the undersigned's name to a Form ID, Form
144, Form 3, Form 4, Form 5, Schedule 13D or Schedule 13G and any amendments
thereto, to be filed with the SEC; and the undersigned does hereby ratify and
confirm all that any of said attorneys and agents shall do or cause to be done
by virtue hereof. The undersigned may revoke the authority granted herein upon
delivering a signed written notice to the foregoing attorneys-in-fact.

Executed on this 6 day of February, 2023.





/s/ Hyukku Lee
-------------------------------
Name: Hyukku Lee
</PRE>
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