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v3.25.1

Shareholders' Equity (Deficit) - outstanding warrants (Details) - American Depositary Shares - $ / shares | 3 Months Ended | 12 Months Ended
--- | --- | ---
Mar. 31, 2025 | Dec. 31, 2024
Class of Warrant or Right [Line Items] |  |
Equity-classified Warrants | 3,519,566 | 3,519,566
Liability-classified Warrants | 11,191,776 | 6,788,077
Warrants exercised | 14,711,342 | 10,307,643
October 2023 Investor Prefunded Warrants |  |
Class of Warrant or Right [Line Items] |  |
Equity-classified Warrants | 48,387 | 48,387
Weighted-Average Exercise Price | $ 0.2 |
March 2025 Series A Investor Warrants |  |
Class of Warrant or Right [Line Items] |  |
Equity-classified Warrants | 2,283,031 | 0
Weighted-Average Exercise Price | $ 0.87 |
March 2030 Series B Investor Warrants |  |
Class of Warrant or Right [Line Items] |  |
Equity-classified Warrants | 2,283,031 | 0
Weighted-Average Exercise Price | $ 0.87 |
May 2024 Investor Warrants |  |
Class of Warrant or Right [Line Items] |  |
Equity-classified Warrants | 4,029,754 | 4,029,754
Weighted-Average Exercise Price | $ 1.77 |
March 2024 Placement Agent Warrants |  |
Class of Warrant or Right [Line Items] |  |
Equity-classified Warrants | 132,061 | 132,061
Weighted-Average Exercise Price | $ 1.85 |
May 2024 Placement Agent Warrants [Member] |  |
Class of Warrant or Right [Line Items] |  |
Equity-classified Warrants | 322,380 | 322,380
Weighted-Average Exercise Price | $ 1.89 |
November 2024 Investor Warrants |  |
Class of Warrant or Right [Line Items] |  |
Equity-classified Warrants | 1,713,402 | 1,713,402
Weighted-Average Exercise Price | $ 2.26 |
October 2023 Placement Agent Warrants |  |
Class of Warrant or Right [Line Items] |  |
Equity-classified Warrants | 42,550 | 42,550
Weighted-Average Exercise Price | $ 4.13 |
March 2022 Investor Warrants |  |
Class of Warrant or Right [Line Items] |  |
Equity-classified Warrants | 186,007 | 186,007
Weighted-Average Exercise Price | $ 28 |
March 2022 Placement Agent Warrants |  |
Class of Warrant or Right [Line Items] |  |
Equity-classified Warrants | 14,874 | 14,874
Weighted-Average Exercise Price | $ 30 |
December 2021 Investor Warrants |  |
Class of Warrant or Right [Line Items] |  |
Equity-classified Warrants | 107,775 | 107,775
Weighted-Average Exercise Price | $ 33 |
December 2021 Placement Agent Warrants |  |
Class of Warrant or Right [Line Items] |  |
Equity-classified Warrants | 8,615 | 8,615
Weighted-Average Exercise Price | $ 35 |
2020 Investor Warrants |  |
Class of Warrant or Right [Line Items] |  |
Equity-classified Warrants | 0 | 139,882
Weighted-Average Exercise Price | $ 44 |
July 2021 Placement Agent Warrants |  |
Class of Warrant or Right [Line Items] |  |
Equity-classified Warrants | 19,909 | 19,909
Weighted-Average Exercise Price | $ 46.4 |
2020 Placement Warrants |  |
Class of Warrant or Right [Line Items] |  |
Equity-classified Warrants | 0 | 22,481
Weighted-Average Exercise Price | $ 51 |
April 2023 Peak Bio Warrants |  |
Class of Warrant or Right [Line Items] |  |
Liability-classified Warrants | 1,187,013 | 1,187,013
Weighted-Average Exercise Price | $ 2.04 |
November 2022 Peak Bio Warrants |  |
Class of Warrant or Right [Line Items] |  |
Liability-classified Warrants | 1,577,556 | 1,577,556
Weighted-Average Exercise Price | $ 39.18 |
Series B warrants | September 2022 Investor Warrants |  |
Class of Warrant or Right [Line Items] |  |
Liability-classified Warrants | 754,997 | 754,997
Weighted-Average Exercise Price | $ 17 |

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