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v3.19.1

COMMITMENTS AND CONTINGENCIES (Details Narrative) - USD ($) |  |  | 1 Months Ended | 12 Months Ended
--- | --- | --- | --- | ---
Sep. 04, 2018 | Aug. 08, 2017 | Nov. 16, 2017 | May 31, 2017 | Oct. 25, 2016 | Jun. 30, 2016 | May 31, 2016 | Dec. 31, 2015 | Jan. 31, 2015 | Sep. 30, 2014 | Dec. 31, 2018 | Dec. 31, 2017
Operating lease periodic payment |  |  |  |  |  |  |  |  | $ 709 |  |  |
Frequency of periodic payment |  |  |  |  |  |  |  |  | Monthly |  |  |
Lease, interest expense |  |  |  |  |  |  |  |  |  |  | $ (967,824) | $ (748,474)
Operating lease rental expense |  |  |  |  |  |  |  |  |  |  | $ 8,651 | 8,502
Operating lease expiration date |  |  |  |  |  |  |  |  | May 31, 2017 |  |  |
Lease agreement description |  |  |  |  |  |  |  |  |  |  | The Company has negotiated and entered into a two-year amendment to that lease that commenced as of June 1, 2017 through May 31, 2019. The monthly rate from June 1, 2017 through May 31, 2018 was $709 per month and increased to $730 per month from June 1, 2018 through May 31, 2019. |
Capital Lease [Member] |  |  |  |  |  |  |  |  |  |  |  |
Lease, interest expense |  |  |  |  |  |  |  |  |  |  | $ 256 | $ 0
Decahedron [Member] |  |  |  |  |  |  |  |  |  |  |  |
Operating lease periodic payment |  |  |  |  | $ 2,430 |  |  |  |  |  |  |
Frequency of periodic payment |  |  |  |  |  |  |  |  |  |  | Monthly | Monthly
Operating lease rental expense |  |  |  |  |  |  |  |  |  |  | $ 39,762 | $ 27,180
Operating lease expiration date |  |  |  |  | Oct. 24, 2021 |  |  |  |  |  |  |
SkyPharm [Member] |  |  |  |  |  |  |  |  |  |  |  |
Operating lease periodic payment |  |  |  | $ 1,432 |  |  |  |  |  | $ 4,955 |  |
Frequency of periodic payment |  |  |  | Monthly |  |  |  |  |  | Monthly |  |
Term of operating lease |  |  |  |  |  |  |  |  |  | 6 years |  |
SkyPharm [Member] | MediHelm S.A. [Member] |  |  |  |  |  |  |  |  |  |  |  |
Operating lease rental expense |  |  |  |  |  |  |  |  |  |  | $ 127,624 | 116,400
Total monthly operating lease amount |  |  |  |  |  |  |  |  |  |  |  | 10,310
SkyPharm [Member] | Additional space [Member] |  |  |  |  |  |  |  |  |  |  |  |
Operating lease periodic payment |  |  |  |  |  | $ 2,091 | $ 916 |  |  |  |  |
Frequency of periodic payment |  |  |  |  |  | Monthly | Monthly |  |  |  |  |
SkyPharm [Member] | First Floor [Member] |  |  |  |  |  |  |  |  |  |  |  |
Operating lease periodic payment |  |  |  |  |  |  |  | $ 916 |  |  |  |
Frequency of periodic payment |  |  |  |  |  |  |  | Monthly |  |  |  |
SkyPharm [Member] | April 18, 2018 [Member] | Advisory Agreement [Member] |  |  |  |  |  |  |  |  |  |  |  |
Term of operating lease |  |  |  |  |  |  |  |  |  |  | 10 years |
Annually operating lease amount |  |  |  |  |  |  |  |  |  |  | $ 104,000 |
Amplerissimo [Member] |  |  |  |  |  |  |  |  |  |  |  |
Operating lease periodic payment |  |  |  |  |  |  |  |  |  |  | $ 110 |
Frequency of periodic payment |  |  |  |  |  |  |  |  |  |  | Monthly |
Operating lease rental expense |  |  |  |  |  |  |  |  |  |  | $ 1,183 | $ 1,492
Operating lease renewal date |  |  |  |  |  |  |  |  |  |  | Jul. 31, 2018 |
Cosmofarm [Member] |  |  |  |  |  |  |  |  |  |  |  |
Frequency of periodic payment |  |  |  |  |  |  |  |  |  |  | Monthly |
Operating lease rental expense |  |  |  |  |  |  |  |  |  |  | $ 1,654 |
Operating lease expiration date |  |  |  |  |  |  |  |  |  |  | Sep. 30, 2018 |
Term of operating lease |  |  |  |  |  |  |  |  |  |  | 10 years |
Total monthly operating lease amount |  |  |  |  |  |  |  |  |  |  | $ 3,809 |
Neos Kosmos [Member] |  |  |  |  |  |  |  |  |  |  |  |
Frequency of periodic payment |  |  |  |  |  |  |  |  |  |  | Monthly |
Operating lease rental expense |  |  |  |  |  |  |  |  |  |  | $ 457 |
Operating lease expiration date |  |  |  |  |  |  |  |  |  |  | May 01, 2017 |
Term of operating lease |  |  |  |  |  |  |  |  |  |  | 3 years |
Anastasios Tsekas and Olga Parthenea Georgatsou [Member] | On October 1, 2016 [Member] | Intellectual property sale agreement [Member] |  |  |  |  |  |  |  |  |  |  |  |
Operating lease periodic payment |  |  |  |  |  |  |  |  |  |  | $ 1,500 |
Common stock shares reserved |  |  |  |  |  |  |  |  |  |  | 200,000 |
Anastasios Tsekas and Olga Parthenea Georgatsou [Member] | On October 1, 2016 [Member] | Intellectual property sale agreement [Member] | Conclusion of Preclinical Trials [Member] |  |  |  |  |  |  |  |  |  |  |  |
Common stock shares reserved |  |  |  |  |  |  |  |  |  |  | 50,000 |
Anastasios Tsekas and Olga Parthenea Georgatsou [Member] | On October 1, 2016 [Member] | Intellectual property sale agreement [Member] | conclusion of Phase I testing [Member] |  |  |  |  |  |  |  |  |  |  |  |
Common stock shares reserved |  |  |  |  |  |  |  |  |  |  | 50,000 |
Anastasios Tsekas and Olga Parthenea Georgatsou [Member] | On October 1, 2016 [Member] | Intellectual property sale agreement [Member] | Conclusion of Phase III testing [Member] |  |  |  |  |  |  |  |  |  |  |  |
Common stock shares reserved |  |  |  |  |  |  |  |  |  |  | 50,000 |
Anastasios Tsekas and Olga Parthenea Georgatsou [Member] | On October 1, 2016 [Member] | Intellectual property sale agreement [Member] | Conclusion of Phase II testing [Member] |  |  |  |  |  |  |  |  |  |  |  |
Common stock shares reserved |  |  |  |  |  |  |  |  |  |  | 50,000 |
Private Placement [Member] |  |  |  |  |  |  |  |  |  |  |  |
Commitments and contingencies description |  | (1) a cash commission of 6% of the total gross proceeds for two named investors (2) a cash commission of 4% of total gross proceeds from five named investors and (3) excluding the five named investors in “(2)” a cash commission equal to 8% of the total gross proceeds from the Offering and the issuance to the Agent or its designees of warrants covering 8% of the shares of common stock issued or issuable by the Company in the Offering. Additionally, the Agent will receive a cash fee of 8% payable within 5 business days, but only in the event of, the receipt by the Company of any cash proceeds from the exercise of any warrants with an expiration equal to or less than 24 months sold in the Offering. |  |  |  |  |  |  |  |  |  |
Cash commission description | In connection with the Company’s September 4, 2018 Note offering, the Agent received a cash commission for this transaction of $140,000, equal to seven (7%) percent of the total gross proceeds of the offering and the issuance of five-year warrants to purchase seven (7%) percent of the shares of Common Stock issued or issuable in this offering (excluding shares of Common Stock issuable upon exercise of any Warrants issued to investors, or 26,056 shares); however, will receive seven (7%) percent of any cash proceeds received from the exercise of any Warrants sold in the offering with an expiration equal to or less than twenty-four (24) months. The Warrants are exercisable six (6) months after the date of issuance, or March 4, 2019. |  | In connection with the Company’s November 16, 2017 Note offering, the Agent received a cash commission of $240,000, equal to eight (8%) percent of the total gross proceeds of the offering and the issuance of five-year warrants to purchase eight (8%) percent of the shares of Common Stock issued or issuable in the offering (excluding shares of Common Stock issuable upon exercise of any Warrants issued to investors, or 53,600 shares); however, will receive eight (8%) percent of any cash proceeds received from the exercise of any Warrants sold in the offering with an expiration equal to or less than twenty-four (24) months. The Warrants are exercisable six (6) months after the date of issuance, or as of May 16, 2018. |  |  |  |  |  |  |  |  |

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