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RELATED PARTY TRANSACTIONS (Details Narrative) - USD ($) |  |  | 1 Months Ended | 3 Months Ended | 9 Months Ended | 12 Months Ended |
--- | --- | --- | --- | --- | --- | --- | ---
May 10, 2021 | Oct. 10, 2020 | Jun. 23, 2021 | Sep. 30, 2021 | Jun. 30, 2021 | Mar. 31, 2021 | Sep. 30, 2020 | Sep. 30, 2021 | Sep. 30, 2020 | Dec. 20, 2018 | Dec. 31, 2020
Accounts payable and accrued expenses |  |  |  | $ 11,712,477 |  |  |  | $ 11,712,477 |  |  | $ 11,973,981
Accrued interest |  |  |  | 936,134 |  |  |  | 936,134 |  |  | 742,374
Net income (loss) |  |  |  | (1,936,543) | $ (2,379,056) | $ (2,173,903) | $ 757,866 | (6,489,502) | $ 1,651,867 |  |
Revenue |  |  |  | 13,595,418 |  |  | 14,352,098 | 40,061,419 | 39,105,318 |  |
Grigorios Siokas Four [Member] |  |  |  |  |  |  |  |  |  |  |
Borrowing |  |  |  | 1,529,500 |  |  |  | 1,529,500 |  |  |
Grigorios Siokas [Member] |  |  |  |  |  |  |  |  |  |  |
Borrowing |  |  |  |  |  |  |  |  |  | $ 1,718,400 |
Litigation settlement | $ 600,000 |  |  |  |  |  |  |  |  |  |
Plantiff attorney fees | 120,000 |  |  |  |  |  |  |  |  |  |
Litigation cost | $ 4,137 |  |  |  |  |  |  |  |  |  |
Accounts payable and accrued expenses |  |  |  | 124,137 |  |  |  | 124,137 |  |  |
Forgiveness to additional paid in capital |  |  |  | 600,000 |  |  |  | 600,000 |  |  |
Outstanding principal balance |  |  |  | 463,080 |  |  |  | 463,080 |  |  | 489,200
Accrued interest |  |  |  | 240,586 |  |  |  | 240,586 |  |  | 193,585
Interest rate |  |  |  |  |  |  |  |  |  | 4.70% |
Maturity date |  |  |  |  |  |  |  |  |  | Mar. 18, 2019 |
Grigorios Siokas Three [Member] |  |  |  |  |  |  |  |  |  |  |
Borrowing |  |  |  | 1,562,895 |  |  |  | 1,562,895 |  |  |
Outstanding principal balance |  |  |  | 3,000,000 |  |  |  | 3,000,000 |  |  | 1,629,246
Convertible share description |  |  | Mr. Siokas whereby an aggregate total of $3,000,000 of these outstanding loans were converted into 500,000 shares of the Company’s common stock |  |  |  |  |  |  |  |
Net income (loss) |  |  |  |  |  |  |  | $ 4,846 |  |  |
Additional proceeds from debt |  |  |  | 1,281,562 |  |  |  |  |  |  |
Repayment of loans |  |  |  | (1,000,000) |  |  |  |  |  |  |
Foreign curreny translation |  |  |  | (20,577) |  |  |  |  |  |  |
Stock converted |  |  |  |  |  |  |  | 166,667 |  |  |
Conversion |  |  |  |  |  |  |  | $ 1,250,000 |  |  |
Description of debt instrument |  |  |  |  |  |  |  | the Company borrowed additional proceeds of €1,350,000 ($1,562,895), €230,000 ($275,306) and $3,993,380 and repaid €106,000 ($122,716) of these loans. Included in the $3,993,380 is a convertible promissory note issued to Mr. Siokas on July 20, 2021 for $2,000,000 in exchange for $2,000,000 in cash proceeds |  |  |
Dimitrios Goulielmos [Member] |  |  |  |  |  |  |  |  |  |  |
Outstanding principal balance |  |  |  | 11,809 |  |  |  | $ 11,809 |  |  | 12,475
Foreign curreny translation |  |  |  | (19,977) |  |  |  |  |  |  |
Loss incured |  |  |  | 26,786 |  |  |  | 26,786 |  |  |
DOC Pharma S.A. [Member] |  |  |  |  |  |  |  |  |  |  |
Payments to purchase products |  |  |  | 761,552 |  |  | 2,441,256 | 2,164,913 | 3,994,896 |  |
Accounts payable balance |  |  |  | 81,457 |  |  |  | 81,457 |  |  |
Accounts receivable balance |  |  |  | 2,924,075 |  |  |  | 2,924,075 |  |  | 3,468,564
Prepaid balance |  |  |  | 2,253,351 |  |  |  | 2,253,351 |  |  | $ 3,468,653
Net prepaid balance |  |  |  | 2,171,893 |  |  |  | 2,171,893 |  |  |
Revenue |  |  |  | $ 44,950 |  |  | $ 208,625 | $ 835,914 | $ 1,696,904 |  |
Description of research and development |  |  |  |  |  |  |  | Design & Development (€725,000); Control and Product Manufacturing (€250,000) and Clinical Study and Research (€450,000). In the nine months ended September 30, 2021, SkyPharm bought 67 licenses at value of €261,300 ($302,507) from Doc Pharma which was the 18.33% of the total cost. The agreement will be terminated on December 31, 2025. |  |  |
DOC Pharma S.A. [Member] | Outsourcing Agreement [Member] |  |  |  |  |  |  |  |  |  |  |
Pieces per product |  | 1,000 |  |  |  |  |  |  |  |  |
Inventroy purchase |  | $ 1,835,603 |  |  |  |  |  |  |  |  |
Agreement term |  | 5 years |  |  |  |  |  |  |  |  |

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