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Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2018 | Jun. 30, 2017 | Jun. 30, 2018 | Jun. 30, 2017
Income Statement [Abstract] |  |  |  |
Revenue | $ 185 |  | $ 376 |
Operating expenses: |  |  |  |
Research and development | (13,725) | $ (5,290) | (24,604) | $ (9,824)
General and administrative | (1,886) | (1,123) | (3,401) | (2,131)
Total operating expenses | (15,611) | (6,413) | (28,005) | (11,955)
Operating loss | (15,426) | (6,413) | (27,629) | (11,955)
Interest (expense) / income, net | (76) | 46 | 9 | 46
Other (expense) / income, net | (177) | 165 | (116) | 97
Total other (expense) / income | (253) | 211 | (107) | 143
Loss before income taxes | (15,679) | (6,202) | (27,736) | (11,812)
Income tax expense | (68) | (78) | (157) | (305)
Net loss and comprehensive loss | (15,747) | (6,280) | (27,893) | (12,117)
Net loss attributable to ordinary shareholders | $ (15,747) | $ (6,280) | $ (27,893) | $ (12,117)
Net loss per share attributable to ordinary shareholders – basic and diluted | $ (2.22) | $ (39.44) | $ (6.72) | $ (82.82)
Weighted average ordinary shares outstanding – basic and diluted | 7,085,655 | 159,221 | 4,148,535 | 146,311

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