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v3.22.1

Commitment and Contingencies - Additional Information (Details) |  |  | 3 Months Ended |
--- | --- | --- | --- | ---
Sep. 08, 2020 Debtinstrument | Jan. 21, 2020 Debtinstrument | Mar. 31, 2022 USD ($) $ / Rnl | Nov. 18, 2015 USD ($)
Royalty-Linked Notes |  |  |  |
Other Commitments [Line Items] |  |  |  |
Debt instrument outstanding portion | $ / Rnl |  |  | 0.04 |
Debt instrument maturity date |  |  | Dec. 31, 2045 |
Debt instrument, aggregate potential payment capped rate |  |  | 4,000 |
Pfizer License Agreement | Royalty-Linked Notes |  |  |  |
Other Commitments [Line Items] |  |  |  |
Debt instrument outstanding portion | $ / Rnl |  |  | 0.04 |
Debt instrument maturity date |  |  | Dec. 31, 2045 |
Debt instrument price per unit |  |  | $ 160.00 |
Debt instrument, aggregate potential payment capped rate |  |  | 4,000 |
Pfizer License Agreement | Royalty-Linked Notes | Private Placement |  |  |  |
Other Commitments [Line Items] |  |  |  |
Number of debt instruments within each notes | Debtinstrument |  | 2,579,400 |  |
Pfizer License Agreement | Royalty-Linked Notes | Rights Offering |  |  |  |
Other Commitments [Line Items] |  |  |  |
Number of debt instruments within each notes | Debtinstrument | 11,000 |  |  |
Pfizer License Agreement | Minimum |  |  |  |
Other Commitments [Line Items] |  |  |  |
Potential future regulatory milestone and sales milestone payments upon achievement of net sales |  |  |  | $ 250,000,000.0
Pfizer License Agreement | Maximum |  |  |  |
Other Commitments [Line Items] |  |  |  |
Potential future regulatory milestone and sales milestone payments upon achievement of net sales |  |  |  | $ 1,000,000,000.0

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- Definition Date when the debt instrument is scheduled to be fully repaid, in YYYY-MM-DD format. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.22(a)(2)) -URI http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682 Reference 2: http://www.xbrl.org/2003/role/exampleRef -Publisher FASB -Name Accounting Standards Codification -Topic 470 -SubTopic 20 -Section 50 -Paragraph 1B -Subparagraph (d) -URI http://asc.fasb.org/extlink&oid=123466505&loc=SL123495323-112611 Reference 3: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 820 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (bbb)(2) -URI http://asc.fasb.org/extlink&oid=123874694&loc=d3e19207-110258 + Details
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