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Royalty-Linked Notes - Additional Information (Details) - Royalty-Linked Notes |  |  | 3 Months Ended
--- | --- | --- | ---
Sep. 08, 2020 Debtinstrument | Jan. 21, 2020 USD ($) Debtinstrument | Mar. 31, 2022 USD ($) $ / Rnl | Mar. 31, 2021 USD ($)
Debt Instrument [Line Items] |  |  |  |
Debt instrument outstanding portion | $ / Rnl |  |  | 0.04 |
Debt instrument maturity date |  |  | Dec. 31, 2045 |
Aggregate amount payable per unit |  |  | $ 160.00 |
Debt instrument, aggregate potential payment capped rate |  |  | 4,000 |
Interest expense |  |  |  | $ 1,204,000
Sulopenem |  |  |  |
Debt Instrument [Line Items] |  |  |  |
Debt discounts |  | $ 1,239,000 |  |
Estimated effective interest rate |  |  | 31.70% |
Private Placement |  |  |  |
Debt Instrument [Line Items] |  |  |  |
Number of debt instruments issued | Debtinstrument |  | 2,579,400 |  |
Rights Offering |  |  |  |
Debt Instrument [Line Items] |  |  |  |
Number of debt instruments issued | Debtinstrument | 11,000 |  |  |

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- Definition Effective interest rate for the funds borrowed under the debt agreement considering interest compounding and original issue discount or premium. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 470 -SubTopic 20 -Section 50 -Paragraph 6 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=123466204&loc=SL6036836-161870 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 835 -SubTopic 30 -Section 45 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=124435984&loc=d3e28551-108399 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 835 -SubTopic 30 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=124429444&loc=SL124452920-239629 Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.22(a)(1)) -URI http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682 + Details
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