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Segment Reporting | 9 Months Ended
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Sep. 30, 2025
Segment Reporting [Abstract] |
Segment Reporting | 13. Segment Reporting In accordance with FASB ASC Topic 280, Segment Reporting, the Company has determined that it operates as a single business segment, which is the development and commercialization of innovative treatments for drug resistant bacterial infections. The financial results of the Company’s operations are managed and reported to the Chief Executive Officer, Chief Financial Officer and Chief Commercial Officer, who together are considered the Company’s chief operating decision maker (CODM), on a consolidated basis. The CODM assesses performance and allocates resources based on the Company’s condensed consolidated statements of operations and key components and processes of the Company’s operations are managed centrally. Segment asset information is not used by the CODM to allocate resources. As a single reportable segment entity, the Company’s segment performance measure is net income / (loss) attributable to shareholders. Significant segment expenses, as provided to the CODM, are presented below:
|  | Three Months Ended |  |  | Nine Months Ended |
|  | September 30, |  |  | September 30, |
|  | 2025 |  |  | 2024 |  |  | 2025 |  |  | 2024 |
Product Revenue, net |  | $ | 390 |  |  | $ | — |  |  | $ | 390 |  |  | $ | — |
Segment cost of sales |  |  | (20 | ) |  |  | — |  |  |  | (20 | ) |  |  | — |
Amortization of intangible asset (a) |  |  | — |  |  |  | — |  |  |  | — |  |  |  | — |
Segment research and development (b) (c) |  |  | (1,244 | ) |  |  | (3,077 | ) |  |  | (2,795 | ) |  |  | (8,998 | )
Segment selling, general and administration (b) (c) |  |  | (6,449 | ) |  |  | (1,734 | ) |  |  | (13,320 | ) |  |  | (5,731 | )
Share-based compensation expense (see Note 15) |  |  | (53 | ) |  |  | (68 | ) |  |  | (170 | ) |  |  | (274 | )
Depreciation and amortization |  |  | (355 | ) |  |  | (8 | ) |  |  | (1,055 | ) |  |  | (23 | )
Operating loss |  | $ | (7,731 | ) |  | $ | (4,887 | ) |  | $ | (16,970 | ) |  | $ | (15,026 | )
a) Amortization expense of $349 and $1,036 related to the Pfizer Intangible Asset has been excluded for the three and nine months ended September 30, 2025, respectively, and included within depreciation and amortization. b) Share-based payment expense of $15 and $50 related to research and development and $38 and $120 related to general and administration have been excluded for the three and nine months ended September 30, 2025, respectively, and included within share-based compensation expense. Share-based payment expense of $25 and $147 related to research and development and $43 and $127 related to general and administration have been excluded for the three and nine months ended September 30, 2024, respectively, and included within share-based compensation expense. c) Depreciation expense of $2 and $7 related to research and development and $4 and $12 related to general and administration have been excluded for the three and nine months ended September 30, 2025, respectively, and included within depreciation and amortization. Depreciation expense of $5 and $14 related to research and development and $3 and $9 related to general and administration have been excluded for the three and nine months ended September 30, 2024, respectively, and included within depreciation and amortization. Interest Expense, Net
|  | Three Months Ended |  |  | Nine Months Ended |
|  | September 30, |  |  | September 30, |
|  | 2025 |  |  | 2024 |  |  | 2025 |  |  | 2024 |
Interest income |  | $ | 121 |  |  | $ | 166 |  |  | $ | 406 |  |  | $ | 607 |
Interest expense |  |  | (562 | ) |  |  | (756 | ) |  |  | (1,697 | ) |  |  | (2,255 | )
Interest expense, net |  | $ | (441 | ) |  | $ | (590 | ) |  | $ | (1,291 | ) |  | $ | (1,648 | )
Long-Lived Assets The distribution of long-lived assets by geographical area was as follows:
Long-lived assets |  | September 30, 2025 |  |  | December 31, 2024 |
Ireland |  | $ | 18,736 |  |  | $ | 19,759 |
U.S. |  |  | 11 |  |  |  | 15 |
Total |  | $ | 18,747 |  |  | $ | 19,774 |

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- Definition The entire disclosure for reporting segments including data and tables. 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