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CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (USD $) In Thousands, except Share data, unless otherwise specified | Total | Series B Preferred Stock | Preferred Stock | Preferred Stock Series B Preferred Stock | Common Stock | Additional Paid-in Capital | Additional Paid-in Capital Series B Preferred Stock | Accumulated Deficit | Accumulated Other Comprehensive Income (Loss)
--- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Balance at Dec. 31, 2011 |  | $ 11,048 us-gaap_StockholdersEquity |  | $ 26 us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_PreferredStockMember |  | $ 46 us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember | [1] | $ 153,442 us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember | [1] |  |  | $ (142,802)us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_RetainedEarningsMember | $ 336 us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_AccumulatedOtherComprehensiveIncomeMember
Balance, shares at Dec. 31, 2011 |  |  |  | 2,586,205 us-gaap_SharesOutstanding / us-gaap_StatementEquityComponentsAxis = us-gaap_PreferredStockMember |  | 4,135,478 us-gaap_SharesOutstanding / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember | [1] |  |  |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |  |  |  |  |  |
Net loss |  | (8,327)us-gaap_NetIncomeLoss |  |  |  |  |  |  |  |  |  | (8,327)us-gaap_NetIncomeLoss / us-gaap_StatementEquityComponentsAxis = us-gaap_RetainedEarningsMember |
Foreign currency translation adjustment |  | 99 us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax |  |  |  |  |  |  |  |  |  |  | 99 us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax / us-gaap_StatementEquityComponentsAxis = us-gaap_AccumulatedOtherComprehensiveIncomeMember
Non-cash stock-based compensation |  | 731 us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue |  |  |  |  |  | 731 us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember | [1] |  |  |  |
Issuance of shares of common stock, shares | [1] |  |  |  |  | 1,667 us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember |  |  |  |  |  |  |
Issuance of shares of common stock |  | 10 us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised |  |  |  | 0 us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember | [1] | 10 us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember | [1] |  |  |  |
Private placement, net, shares | [1] |  |  |  |  | 1,833,333 us-gaap_StockIssuedDuringPeriodSharesNewIssues / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember |  |  |  |  |  |  |
Stock issued during period |  | 17,373 us-gaap_StockIssuedDuringPeriodValueNewIssues |  |  |  | 18 us-gaap_StockIssuedDuringPeriodValueNewIssues / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember | [1] | 17,355 us-gaap_StockIssuedDuringPeriodValueNewIssues / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember | [1] |  |  |  |
Dividends on preferred stock |  | (660)us-gaap_DividendsPreferredStockCash |  |  |  |  |  |  |  |  |  | (660)us-gaap_DividendsPreferredStockCash / us-gaap_StatementEquityComponentsAxis = us-gaap_RetainedEarningsMember |
Balance at Dec. 31, 2012 |  | 20,274 us-gaap_StockholdersEquity |  | 26 us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_PreferredStockMember |  | 64 us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember | [1] | 171,538 us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember | [1] |  |  | (151,789)us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_RetainedEarningsMember | 435 us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_AccumulatedOtherComprehensiveIncomeMember
Balance, shares at Dec. 31, 2012 |  |  |  | 2,586,205 us-gaap_SharesOutstanding / us-gaap_StatementEquityComponentsAxis = us-gaap_PreferredStockMember |  | 5,970,478 us-gaap_SharesOutstanding / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember | [1] |  |  |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |  |  |  |  |  |
Net loss |  | (15,987)us-gaap_NetIncomeLoss |  |  |  |  |  |  |  |  |  | (15,987)us-gaap_NetIncomeLoss / us-gaap_StatementEquityComponentsAxis = us-gaap_RetainedEarningsMember |
Foreign currency translation adjustment |  | (45)us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax |  |  |  |  |  |  |  |  |  |  | (45)us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax / us-gaap_StatementEquityComponentsAxis = us-gaap_AccumulatedOtherComprehensiveIncomeMember
Non-cash stock-based compensation |  | 360 us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue |  |  |  |  |  | 360 us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember | [1] |  |  |  |
Private placement, net, shares | [1] |  |  |  |  | 1,383,217 us-gaap_StockIssuedDuringPeriodSharesNewIssues / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember |  |  |  |  |  |  |
Stock issued during period |  | 7,570 us-gaap_StockIssuedDuringPeriodValueNewIssues |  |  |  | 14 us-gaap_StockIssuedDuringPeriodValueNewIssues / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember | [1] | 7,556 us-gaap_StockIssuedDuringPeriodValueNewIssues / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember | [1] |  |  |  |
Dividends on preferred stock |  | (726)us-gaap_DividendsPreferredStockCash |  |  |  |  |  |  |  |  |  | (726)us-gaap_DividendsPreferredStockCash / us-gaap_StatementEquityComponentsAxis = us-gaap_RetainedEarningsMember |
Other |  | 0 us-gaap_StockholdersEquityOther |  |  |  | (5)us-gaap_StockholdersEquityOther / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember | [1] | 5 us-gaap_StockholdersEquityOther / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember | [1] |  |  |  |
Balance at Dec. 31, 2013 |  | 11,446 us-gaap_StockholdersEquity |  | 26 us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_PreferredStockMember |  | 73 us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember | [1] | 179,459 us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember | [1] |  |  | (168,502)us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_RetainedEarningsMember | 390 us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_AccumulatedOtherComprehensiveIncomeMember
Balance, shares at Dec. 31, 2013 |  |  |  | 2,586,205 us-gaap_SharesOutstanding / us-gaap_StatementEquityComponentsAxis = us-gaap_PreferredStockMember |  | 7,353,695 us-gaap_SharesOutstanding / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember | [1] |  |  |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |  |  |  |  |  |
Net loss |  | (13,942)us-gaap_NetIncomeLoss |  |  |  |  |  |  |  |  |  | (13,942)us-gaap_NetIncomeLoss / us-gaap_StatementEquityComponentsAxis = us-gaap_RetainedEarningsMember |
Foreign currency translation adjustment |  | (50)us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax |  |  |  |  |  |  |  |  |  |  | (50)us-gaap_OtherComprehensiveIncomeLossForeignCurrencyTransactionAndTranslationAdjustmentNetOfTax / us-gaap_StatementEquityComponentsAxis = us-gaap_AccumulatedOtherComprehensiveIncomeMember
Non-cash stock-based compensation |  | 977 us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue |  |  |  |  |  | 977 us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember | [1] |  |  |  |
Private placement, net, shares | [1] |  |  |  |  | 730,776 us-gaap_StockIssuedDuringPeriodSharesNewIssues / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember |  |  |  |  |  |  |
Stock issued during period |  | 2,361 us-gaap_StockIssuedDuringPeriodValueNewIssues | 6,905 us-gaap_StockIssuedDuringPeriodValueNewIssues / us-gaap_StatementClassOfStockAxis = us-gaap_SeriesBPreferredStockMember |  | 14 us-gaap_StockIssuedDuringPeriodValueNewIssues / us-gaap_StatementClassOfStockAxis = us-gaap_SeriesBPreferredStockMember / us-gaap_StatementEquityComponentsAxis = us-gaap_PreferredStockMember | 8 us-gaap_StockIssuedDuringPeriodValueNewIssues / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember | [1] | 2,353 us-gaap_StockIssuedDuringPeriodValueNewIssues / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember | [1] | 6,891 us-gaap_StockIssuedDuringPeriodValueNewIssues / us-gaap_StatementClassOfStockAxis = us-gaap_SeriesBPreferredStockMember / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember | [1] |  |
Dividends on preferred stock |  | (1,144)us-gaap_DividendsPreferredStockCash |  |  |  |  |  |  |  |  |  | (1,144)us-gaap_DividendsPreferredStockCash / us-gaap_StatementEquityComponentsAxis = us-gaap_RetainedEarningsMember |
Preferred stock agreement, shares |  |  |  |  | 1,443,297 tbio_PreferredStockIssuedDuringPeriodSharesNewIssues / us-gaap_StatementClassOfStockAxis = us-gaap_SeriesBPreferredStockMember / us-gaap_StatementEquityComponentsAxis = us-gaap_PreferredStockMember |  |  |  |  |  |  |  |
Balance at Dec. 31, 2014 |  | $ 6,553 us-gaap_StockholdersEquity |  | $ 40 us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_PreferredStockMember |  | $ 81 us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember | [1] | $ 189,680 us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember | [1] |  |  | $ (183,588)us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_RetainedEarningsMember | $ 340 us-gaap_StockholdersEquity / us-gaap_StatementEquityComponentsAxis = us-gaap_AccumulatedOtherComprehensiveIncomeMember
Balance, shares at Dec. 31, 2014 |  |  |  | 4,029,502 us-gaap_SharesOutstanding / us-gaap_StatementEquityComponentsAxis = us-gaap_PreferredStockMember |  | 8,084,471 us-gaap_SharesOutstanding / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember | [1] |  |  |  |  |  |
[1] | The common stock shares and additional paid-in capital for all periods presented reflect the one-for-twelve reverse stock split which took effect on January 27, 2014.

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- Definition Total of all stockholders' equity (deficit) items, net of receivables from officers, directors, owners, and affiliates of the entity which are attributable to the parent. The amount of the economic entity's stockholders' equity attributable to the parent excludes the amount of stockholders' equity which is allocable to that ownership interest in subsidiary equity which is not attributable to the parent (noncontrolling interest, minority interest). This excludes temporary equity and is sometimes called permanent equity. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 310 -SubTopic 10 -Section S99 -Paragraph 2 -Subparagraph (SAB TOPIC 4.E) -URI http://asc.fasb.org/extlink&oid=27010918&loc=d3e74512-122707 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Staff Accounting Bulletin (SAB) -Number Topic 4 -Section E Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.29-31) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 02 -Paragraph 29, 30, 31 -Article 5 + Details
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Balance Type: | credit
Period Type: | duration